Zobrazeno 1 - 10
of 330
pro vyhledávání: '"Jean‐Pierre Brion"'
Autor:
Neha Basheer, Luc Buee, Jean-Pierre Brion, Tomas Smolek, Muhammad Khalid Muhammadi, Jozef Hritz, Tomas Hromadka, Ilse Dewachter, Susanne Wegmann, Isabelle Landrieu, Petr Novak, Amritpal Mudher, Norbert Zilka
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-31 (2024)
Abstract The transcellular propagation of the aberrantly modified protein tau along the functional brain network is a key hallmark of Alzheimer's disease and related tauopathies. Inoculation-based tau propagation models can recapitulate the stereotyp
Externí odkaz:
https://doaj.org/article/0547cc546b564dafa9cf1056d3b05ad1
Autor:
Siranjeevi Nagaraj, Carolina Quintanilla-Sánchez, Kunie Ando, Lidia Lopez-Gutierrez, Emilie Doeraene, Andreea-Claudia Kosa, Emmanuel Aydin, Jean-Pierre Brion, Karelle Leroy
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Alzheimer’s disease (AD) affects the elderly population by causing memory impairments, cognitive and behavioral abnormalities. Currently, no curative treatments exist, emphasizing the need to explore therapeutic options that modify the progression
Externí odkaz:
https://doaj.org/article/e4d1395d751140928dd95be8672c8ada
Autor:
Kunie Ando, Lorenzo Ferlini, Valérie Suain, Zehra Yilmaz, Salwa Mansour, Isabelle Le Ber, Cécile Bouchard, Karelle Leroy, Alexandra Durr, Fabienne Clot, Marie Sarazin, Jean-Christophe Bier, Jean-Pierre Brion
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-4 (2020)
Externí odkaz:
https://doaj.org/article/5d27c16f0c9d4419b2b9151ff3a7f20c
Autor:
Kunie Ando, Marième Ndjim, Sabrina Turbant, Gaëlle Fontaine, Gustavo Pregoni, Luce Dauphinot, Zehra Yilmaz, Valérie Suain, Salwa Mansour, Michèle Authelet, Robert De Dekker, Karelle Leroy, Benoît Delatour, Brain Bank NeuroCEB Neuropathology Network, Charles Duyckaerts, Marie-Claude Potier, Jean-Pierre Brion
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-15 (2020)
Abstract Synaptojanin 1 (SYNJ1) is a brain-enriched lipid phosphatase critically involved in autophagosomal/endosomal trafficking, synaptic vesicle recycling and metabolism of phosphoinositides. Previous studies suggest that SYNJ1 polymorphisms have
Externí odkaz:
https://doaj.org/article/0a052a9fe57e48cdaf033a75854e03be
Autor:
Kunie Ando, Siranjeevi Nagaraj, Fahri Küçükali, Marie-Ange de Fisenne, Andreea-Claudia Kosa, Emilie Doeraene, Lidia Lopez Gutierrez, Jean-Pierre Brion, Karelle Leroy
Publikováno v:
Cells, Vol 11, Iss 24, p 3994 (2022)
Genome-wide association studies (GWAS) have identified the PICALM (Phosphatidylinositol binding clathrin-assembly protein) gene as the most significant genetic susceptibility locus after APOE and BIN1. PICALM is a clathrin-adaptor protein that plays
Externí odkaz:
https://doaj.org/article/f918cd0341824cfe89038a7f5b0d2b92
Autor:
Francisco Sáez-Orellana, Thomas Leroy, Floriane Ribeiro, Anna Kreis, Karelle Leroy, Fanny Lalloyer, Eric Baugé, Bart Staels, Charles Duyckaerts, Jean-Pierre Brion, Philippe Gailly, Jean-Noël Octave, Nathalie Pierrot
Publikováno v:
JCI Insight, Vol 6, Iss 16 (2021)
Among genetic susceptibility loci associated with late-onset Alzheimer disease (LOAD), genetic polymorphisms identified in genes encoding lipid carriers led to the hypothesis that a disruption of lipid metabolism could promote disease progression. We
Externí odkaz:
https://doaj.org/article/e8a9b89247db4df9868a05e462a785d5
Autor:
Sarah Houben, Karelle Leroy, Kunie Ando, Zehra Yilmaz, Cyprien Widomski, Luc Buée, Jean-Pierre Brion
Publikováno v:
Neurobiology of Disease, Vol 127, Iss , Pp 131-141 (2019)
Impaired adult hippocampal neurogenesis has been reported as a feature of Alzheimer's disease and other tauopathies and might contribute to defects in learning and memory in these diseases. To assess the interference of tau pathology, a common key-le
Externí odkaz:
https://doaj.org/article/ae2d3ec459a04dc88fe9430d374c9171
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Adult hippocampal neurogenesis (AHN) has been widely confirmed in mammalian brains. A growing body of evidence points to the fact that AHN sustains hippocampal-dependent functions such as learning and memory. Impaired AHN has been reported in post-mo
Externí odkaz:
https://doaj.org/article/5cbf41abf0f8455791ee44e771fbb326
Autor:
Kunie Ando, Christophe Erneux, Mégane Homa, Sarah Houben, Marie-Ange de Fisenne, Jean-Pierre Brion, Karelle Leroy
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Externí odkaz:
https://doaj.org/article/843da825445b49a092bb80b8010945a0
Autor:
Kunie Ando, Sarah Houben, Mégane Homa, Marie-Ange de Fisenne, Marie-Claude Potier, Christophe Erneux, Jean-Pierre Brion, Karelle Leroy
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2021)
Externí odkaz:
https://doaj.org/article/ee704f4fb63f4baf80bc98b7011b3810