Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Jean‐Philippe Theurillat"'
Autor:
Torben Redmer, Martin Raigel, Christina Sternberg, Roman Ziegler, Clara Probst, Desiree Lindner, Astrid Aufinger, Tanja Limberger, Karolina Trachtova, Petra Kodajova, Sandra Högler, Michaela Schlederer, Stefan Stoiber, Monika Oberhuber, Marco Bolis, Heidi A. Neubauer, Sara Miranda, Martina Tomberger, Nora S. Harbusch, Ines Garces de los Fayos Alonso, Felix Sternberg, Richard Moriggl, Jean-Philippe Theurillat, Boris Tichy, Vojtech Bystry, Jenny L. Persson, Stephan Mathas, Fritz Aberger, Birgit Strobl, Sarka Pospisilova, Olaf Merkel, Gerda Egger, Sabine Lagger, Lukas Kenner
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Background Prostate cancer develops through malignant transformation of the prostate epithelium in a stepwise, mutation-driven process. Although activator protein-1 transcription factors such as JUN have been implicated as potential oncogeni
Externí odkaz:
https://doaj.org/article/adefb22c8cb94d6696ce31c1da5a32f5
Autor:
Veronica Cocetta, Manuel Zorzi, Stefano Bejor, Maria Candida Cesta, Maria De Pizzol, Jean-Philippe Theurillat, Marcello Allegretti, Andrea Alimonti, Monica Montopoli, Massimo Rugge
Publikováno v:
Life, Vol 14, Iss 9, p 1107 (2024)
Since the beginning of the COVID-19 pandemic, it has been evident that women and young people were less susceptible to severe infections compared to males. In a previous study, we observed a reduced prevalence of SARS-CoV-2 infections in hormonal-dri
Externí odkaz:
https://doaj.org/article/4db01f065acd464298d89a404b99151d
Autor:
Sofia Karkampouna, Federico La Manna, Andrej Benjak, Mirjam Kiener, Marta De Menna, Eugenio Zoni, Joël Grosjean, Irena Klima, Andrea Garofoli, Marco Bolis, Arianna Vallerga, Jean-Philippe Theurillat, Maria R. De Filippo, Vera Genitsch, David Keller, Tijmen H. Booij, Christian U. Stirnimann, Kenneth Eng, Andrea Sboner, Charlotte K. Y. Ng, Salvatore Piscuoglio, Peter C. Gray, Martin Spahn, Mark A. Rubin, George N. Thalmann, Marianna Kruithof-de Julio
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
To date, patients still succumb to cancer, due to tumors not responding to therapy or ultimately acquiring resistance. Here the authors show that by exploiting patient derived organoids and a treatment-naïve patient derived xenograft, patient therap
Externí odkaz:
https://doaj.org/article/74f8126482f64e7aa57d9156cdf767c0
Autor:
Domenico Albino, Martina Falcione, Valeria Uboldi, Dada Oluwaseyi Temilola, Giada Sandrini, Jessica Merulla, Gianluca Civenni, Aleksandra Kokanovic, Alessandra Stürchler, Dheeraj Shinde, Mariangela Garofalo, Ricardo Pereira Mestre, Vera Constâncio, Martha Wium, Jacopo Burrello, Nicolò Baranzini, Annalisa Grimaldi, Jean-Philippe Theurillat, Daniela Bossi, Lucio Barile, Rui M. Henrique, Carmen Jeronimo, Luiz Fernando Zerbini, Carlo V. Catapano, Giuseppina M. Carbone
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Following on reports that miR-424 expression promotes oncogenesis, Domenico Albino et al. find that extracellular vesicles (EVs) in the plasma of prostate cancer patients secrete miR-424. Using cell-based and animal models, they demonstrate that EV-m
Externí odkaz:
https://doaj.org/article/28200d6da1754aecbc8751a32e04f961
Autor:
Monika Oberhuber, Matteo Pecoraro, Mate Rusz, Georg Oberhuber, Maritta Wieselberg, Peter Haslinger, Elisabeth Gurnhofer, Michaela Schlederer, Tanja Limberger, Sabine Lagger, Jan Pencik, Petra Kodajova, Sandra Högler, Georg Stockmaier, Sandra Grund‐Gröschke, Fritz Aberger, Marco Bolis, Jean‐Philippe Theurillat, Robert Wiebringhaus, Theresa Weiss, Andrea Haitel, Marc Brehme, Wolfgang Wadsak, Johannes Griss, Thomas Mohr, Alexandra Hofer, Anton Jäger, Jürgen Pollheimer, Gerda Egger, Gunda Koellensperger, Matthias Mann, Brigitte Hantusch, Lukas Kenner
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 4, Pp 1-27 (2020)
Abstract Prostate cancer (PCa) has a broad spectrum of clinical behavior; hence, biomarkers are urgently needed for risk stratification. Here, we aim to find potential biomarkers for risk stratification, by utilizing a gene co‐expression network of
Externí odkaz:
https://doaj.org/article/2a34435eaf574feab86239c627dd739f
Autor:
Carlotta Cecchini, Sébastien Tardy, Valentina Ceserani, Jean-Philippe Theurillat, Leonardo Scapozza
Publikováno v:
CHIMIA, Vol 74, Iss 4, Pp 274-277 (2020)
In the context of dysregulated ubiquitylation, the accumulation of oncogenic substrates can lead to tumorigenesis. In particular, mutations in Von Hippel-Lindau (VHL) E3 ubiquitin ligase are related to overexpression of hypoxia-inducible factors (HIF
Externí odkaz:
https://doaj.org/article/0d58a029bbd34270b5cab9e09f786811
Autor:
Ning Li, Fernando Canale, Camilla Basso, Anna Sokolovska, Michela Perotti, Michael James, Wenjie Jin, Jean-Philippe Theurillat, Daniel Leventhal, Kip West, Jose Lora, Federica Sallusto, Roger Geiger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/a0be3067cdbb4c43b08fc905e02ccd77
Autor:
Levi A. Garraway, Angela N. Koehler, Lucienne Ronco, Raymond Pagliarini, Douglas S. Daniels, Fallon Lin, Elizabeth K. Culyba, Cheng Zhong, Timothy A. Lewis, Emily C. Hartman, Jean-Philippe Theurillat, Colin W. Garvie, Nicolas Stransky, Marius S. Pop
Members of the ETS transcription factor family have been implicated in several cancers, where they are often dysregulated by genomic derangement. ETS variant 1 (ETV1) is an ETS factor gene that undergoes chromosomal translocation in prostate cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b7be6ddfbcc316a35352a8de524552
https://doi.org/10.1158/1535-7163.c.6536437
https://doi.org/10.1158/1535-7163.c.6536437
Autor:
Levi A. Garraway, Angela N. Koehler, Lucienne Ronco, Raymond Pagliarini, Douglas S. Daniels, Fallon Lin, Elizabeth K. Culyba, Cheng Zhong, Timothy A. Lewis, Emily C. Hartman, Jean-Philippe Theurillat, Colin W. Garvie, Nicolas Stransky, Marius S. Pop
PDF file - 115K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8770a02253b111f21b0645a8ce4160
https://doi.org/10.1158/1535-7163.22500397.v1
https://doi.org/10.1158/1535-7163.22500397.v1
Autor:
Levi A. Garraway, Angela N. Koehler, Lucienne Ronco, Raymond Pagliarini, Douglas S. Daniels, Fallon Lin, Elizabeth K. Culyba, Cheng Zhong, Timothy A. Lewis, Emily C. Hartman, Jean-Philippe Theurillat, Colin W. Garvie, Nicolas Stransky, Marius S. Pop
PDF file - 1496K, Figure S1 - control expression and SMM hits representation; luciferase assay with MITF for BRD32048 and luciferase assay using BRD32048 analogs. Figure S2 - SPR data control graphs for TBX21 reference experiment. Figure S3 alternati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021b9c78d1d5e38f9008cb87d32d7958
https://doi.org/10.1158/1535-7163.22500400
https://doi.org/10.1158/1535-7163.22500400