Zobrazeno 1 - 10
of 231
pro vyhledávání: '"Jean‐Philippe Merlio"'
Autor:
Rémy Nicolle, Cindy Canivet, Laurent Palazzo, Bertrand Napoléon, Mira Ayadi, Camille Pignolet, Jérôme Cros, Sophie Gourgou, Janick Selves, Jérôme Torrisani, Nelson Dusetti, Pierre Cordelier, Louis Buscail, Barbara Bournet, Nicolas Carrère, Fabrice Muscari, Bertrand Suc, Rosine Guimbaud, Corinne Couteau, Marion Deslandres, Pascale Rivera, Emily Alouany, Nadim Fares, Karl Barange, Anne Gomez-Brouchet, Adrian Culetto, Guillaume Le Cosquer, Marion Jaffrelot, Bertrand Pujol, Fabien Fumex, Jérôme Desrame, Christine Lefort, Vincent Lepilliez, Rodica Gincul, Pascal Artru, Léa Clavel, Anne-Isabelle Lemaistre, Sarah Tubiana, Nicolas Flori, Pierre Senesse, Pierre-Emmanuel Colombo, Emmanuelle Samalin-Scalzi, Fabienne Portales, Lise Roca, Claire Honfo Ga, Carinne Plassot, Marc Ychou, Pierre Guibert, Christelle De La Fouchardière, Mathieu Sarabi, Patrice Peyrat, Séverine Tabone-Eglinger, Caroline Renard, Guillaume Piessen, Stéphanie Truant, Alain Saudemont, Guillaume Millet, Florence Renaud, Emmanuelle Leteurtre, Patrick Gelé, Eric Assenat, Jean-Michel Fabre, François-Régis Souche, Marie Dupuy, Anne-Marie Gorce-Dupuy, Jeanne Ramos, Jean-François Seitz, Jean Hardwigsen, Emmanuelle Norguet-Monnereau, Philippe Grandval, Muriel Duluc, Dominique Figarella-Branger, Véronique Vendrely, Clément Subtil, Eric Terrebonne, Jean-Frédéric Blanc, Jean-Philippe Merlio, Dominique Farges-Bancel, Jean-Marc Gornet, Daniela Geromin, Geoffroy Vanbiervliet, Anne-Claire Frin, Delphine Ouvrier, Marie-Christine Saint-Paul, Philippe Berthélémy, Chelbabi Fouad, Stéphane Garcia, Nathalie Lesavre, Mohamed Gasmi, Marc Barthet, Vanessa Cottet, Cyrille Delpierre
Publikováno v:
EBioMedicine, Vol 109, Iss , Pp 105373- (2024)
Summary: Background: We apply endoscopic ultrasound-guided fine needle aspiration biopsy to cytopathologically diagnose and sample nucleic acids from primary tumours regardless of the disease stage. Methods: 397 patients with proven pancreatic adenoc
Externí odkaz:
https://doaj.org/article/42b1e90f321d4eb681ad93fd73b2d3f5
Autor:
Alain Chebly, Joana Ropio, Jean‐Marie Peloponese, Sandrine Poglio, Martina Prochazkova‐Carlotti, Floriane Cherrier, Jacky Ferrer, Yamina Idrissi, Evelyne Segal‐Bendirdjian, Eliane Chouery, Chantal Farra, Anne Pham‐Ledard, Marie Beylot‐Barry, Jean‐Philippe Merlio, Roland Tomb, Edith Chevret
Publikováno v:
Molecular Oncology, Vol 16, Iss 9, Pp 1931-1946 (2022)
Cutaneous T‐cell lymphomas (CTCLs) are telomerase‐positive tumors expressing hTERT, although neither gene rearrangement/amplification nor promoter hotspot mutations could explain the hTERT re‐expression. As the hTERT promoter is rich in CpG, we
Externí odkaz:
https://doaj.org/article/819e3dd1237742258055914e28ab5f6e
Autor:
Joana Ropio, Alain Chebly, Jacky Ferrer, Martina Prochazkova‐Carlotti, Yamina Idrissi, Lamia Azzi‐Martin, David Cappellen, Anne Pham‐Ledard, Paula Soares, Jean‐Philippe Merlio, Edith Chevret
Publikováno v:
Cancer Medicine, Vol 9, Iss 9, Pp 3153-3162 (2020)
Abstract Background Telomere shortening is linked to a range of different human diseases, hence reliable measurement methods are needed to uncover such associations. Among the plethora of telomere length measurement methods, qPCR is reported as easy
Externí odkaz:
https://doaj.org/article/9ded3b0c41f34a3d929b2ad0821724c2
Autor:
Audrey Gros, Sarah Menguy, Victor Bobée, Océane Ducharme, Isabelle Cirilo Cassaigne, Béatrice Vergier, Marie Parrens, Marie Beylot-Barry, Anne Pham-Ledard, Philippe Ruminy, Fabrice Jardin, Jean-Philippe Merlio
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0266978 (2022)
Primary cutaneous large B-cell lymphomas (PCLBCL) represent a diagnostic challenge because they are classified as PCLBCL, leg type (PCLBCL, LT) or primary cutaneous follicle centre lymphoma, large cell (PCFCL, LC), which differ by prognosis and thera
Externí odkaz:
https://doaj.org/article/aecf8928990d436ea182e22637e13487
Autor:
Alain Chebly, Martina Prochazkova-Carlotti, Yamina Idrissi, Laurence Bresson-Bepoldin, Sandrine Poglio, Chantal Farra, Marie Beylot-Barry, Jean-Philippe Merlio, Roland Tomb, Edith Chevret
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Sézary syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell lymphomas (CTCL) in which the human Telomerase Reverse Transcriptase (hTERT) gene is re-expressed. Current available treatments do not provide long-term response. We previous
Externí odkaz:
https://doaj.org/article/b63f3a7499bf46459af38bc1273e7c5f
Next-Generation Cancer Biomarkers: Extracellular Vesicle DNA as a Circulating Surrogate of Tumor DNA
Autor:
Samuel Amintas, Véronique Vendrely, Charles Dupin, Louis Buscail, Christophe Laurent, Barbara Bournet, Jean-Philippe Merlio, Aurélie Bedel, François Moreau-Gaudry, Julian Boutin, Sandrine Dabernat, Etienne Buscail
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Extracellular vesicles (EVs) are produced by healthy tissues and tumor cells and are released in various bodily fluids, including blood. They are limited by bilayer phospholipidic membranes, and they carry a rich content in biomolecules. Their releas
Externí odkaz:
https://doaj.org/article/8b80cec79fc643f28a9fb04db7bebb51
Autor:
Alain Chebly, Jean-Marie Peloponese, Evelyne Ségal-Bendirdjian, Jean-Philippe Merlio, Roland Tomb, Edith Chevret
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/11f49aa4fcfa404cadd0a4d36d9c1c77
Autor:
Anne-Marie Ruppert, MD, PhD, Michèle Beau-Faller, MD, PhD, Didier Debieuvre, MD, L’Houcine Ouafik, MD, PhD, Virginie Westeel, MD PhD, Isabelle Rouquette, MD, Julien Mazières, MD, PhD, Pierre-Paul Bringuier, MD, Isabelle Monnet, MD, Fabienne Escande, MD, Charles Ricordel, MD, Jean-Philippe Merlio, MD, PDh, Henri Janicot, MD, Antoinette Lemoine, MD, PhD, Pascal Foucher, MD, Michel Poudenx, MD, Franck Morin, MSc, Alexandra Langlais, MSc, Pierre-Jean Souquet, MD, PhD, Fabrice Barlesi, MD, PhD, Marie Wislez, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 1, Iss 3, Pp 100052- (2020)
Introduction: KRAS mutations are detected in 20% to 30% of NSCLC. However, KRAS mutation subtypes may differently influence the outcome of patients with advanced NSCLC. Methods: In the Biomarkers France study, 4894 KRAS mutations (26.2%) were detecte
Externí odkaz:
https://doaj.org/article/0738da11c0534bb49bbf4eba273784d4
Autor:
Samuel Amintas, Aurélie Bedel, François Moreau-Gaudry, Julian Boutin, Louis Buscail, Jean-Philippe Merlio, Véronique Vendrely, Sandrine Dabernat, Etienne Buscail
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2653 (2020)
The presence of circulating tumor cells (CTCs) and CTC clusters, also known as tumor microemboli, in biological fluids has long been described. Intensive research on single CTCs has made a significant contribution in understanding tumor invasion, met
Externí odkaz:
https://doaj.org/article/b55b9e906f8a4afeb112aaf0eade84ad
Autor:
Audrey Gros, Elodie Laharanne, Marie Vergier, Martina Prochazkova-Carlotti, Anne Pham-Ledard, Thomas Bandres, Sandrine Poglio, Sabine Berhouet, Béatrice Vergier, Jean-Philippe Vial, Edith Chevret, Marie Beylot-Barry, Jean-Philippe Merlio
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173171 (2017)
Recent massive parallel sequencing data have evidenced the genetic diversity and complexity of Sézary syndrome mutational landscape with TP53 alterations being the most prevalent genetic abnormality. We analyzed a cohort of 35 patients with SS and a
Externí odkaz:
https://doaj.org/article/b135f7b5173749eaaea80d17cfc7e022