Zobrazeno 1 - 10
of 622
pro vyhledávání: '"Jean‐Paul Thiery"'
Autor:
Jing-Yu Wang, Xiao-Ping Zhang, Hong-Kun Zhou, Hong-Xin Cai, Jin-Biao Xu, Bao-Gang Xie, Jean-Paul Thiery, Wu Zhou
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract RNA interactomes and their diversified functionalities have recently benefited from critical methodological advances leading to a paradigm shift from a conventional conception on the regulatory roles of RNA in pathogenesis. However, the dyna
Externí odkaz:
https://doaj.org/article/aaf2b5f259cc4c7ab235a25c338a8aeb
Autor:
Agnete S. T. Engelsen, Maria L. Lotsberg, Raefa Abou Khouzam, Jean-Paul Thiery, James B. Lorens, Salem Chouaib, Stéphane Terry
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The development and implementation of Immune Checkpoint Inhibitors (ICI) in clinical oncology have significantly improved the survival of a subset of cancer patients with metastatic disease previously considered uniformly lethal. However, the low res
Externí odkaz:
https://doaj.org/article/2325540166db4535942a5d6fcd305dd0
Publikováno v:
Chinese Medicine, Vol 14, Iss 1, Pp 1-13 (2019)
Abstract Epithelial–mesenchymal transition (EMT) is a critical biological process allowing epithelial cells to de-differentiate into mesenchymal cells. Orchestrated signaling pathways cooperatively induce EMT and effect physiological, sometimes pat
Externí odkaz:
https://doaj.org/article/ef4581c0015349a18df733848cd777cf
Autor:
Katyana Amilca-Seba, Tuan Zea Tan, Jean-Paul Thiery, Lila Louadj, Sandrine Thouroude, Anaïs Bouygues, Michèle Sabbah, Annette K. Larsen, Jérôme A. Denis
Publikováno v:
Cells, Vol 11, Iss 11, p 1808 (2022)
In colorectal cancer (CRC), disease-related death is closely linked to tumor aggressiveness and metastasis. Gene expression profiling of patient tumors has suggested that a more mesenchymal phenotype, present in about one-fourth of all patients, is a
Externí odkaz:
https://doaj.org/article/2982f02a2cdf41398d3f6e0eadaa2c2c
Autor:
Claudia Koch, Andra Kuske, Simon A Joosse, Gökhan Yigit, George Sflomos, Sonja Thaler, Daniel J Smit, Stefan Werner, Kerstin Borgmann, Sebastian Gärtner, Parinaz Mossahebi Mohammadi, Laura Battista, Laure Cayrefourcq, Janine Altmüller, Gabriela Salinas‐Riester, Kaamini Raithatha, Arne Zibat, Yvonne Goy, Leonie Ott, Kai Bartkowiak, Tuan Zea Tan, Qing Zhou, Michael R Speicher, Volkmar Müller, Tobias M Gorges, Manfred Jücker, Jean‐Paul Thiery, Cathrin Brisken, Sabine Riethdorf, Catherine Alix‐Panabières, Klaus Pantel
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 9, Pp n/a-n/a (2020)
Abstract Functional studies giving insight into the biology of circulating tumor cells (CTCs) remain scarce due to the low frequency of CTCs and lack of appropriate models. Here, we describe the characterization of a novel CTC‐derived breast cancer
Externí odkaz:
https://doaj.org/article/6fcb45740e9c4955a376a11179160a9e
Autor:
Anh Viet-Phuong Le, Marcin Szaumkessel, Tuan Zea Tan, Jean-Paul Thiery, Erik W. Thompson, Alexander Dobrovic
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2553 (2018)
(1) Background: Epithelial–mesenchymal plasticity (EMP) is a dynamic process whereby epithelial carcinoma cells reversibly acquire morphological and invasive characteristics typical of mesenchymal cells. Identifying the methylation differences betw
Externí odkaz:
https://doaj.org/article/54fd1b9c2697426ab3598905cdcde541
Autor:
Benjamin Toh, Xiaojie Wang, Jo Keeble, Wen Jing Sim, Karen Khoo, Wing-Cheong Wong, Masashi Kato, Armelle Prevost-Blondel, Jean-Paul Thiery, Jean-Pierre Abastado
Publikováno v:
PLoS Biology, Vol 9, Iss 9, p e1001162 (2011)
In order to metastasize, cancer cells need to acquire a motile phenotype. Previously, development of this phenotype was thought to rely on the acquisition of selected, random mutations and thus would occur late in cancer progression. However, recent
Externí odkaz:
https://doaj.org/article/f44fa3332e3745aa89fe92e74ac7d26f
Autor:
Joel A Malek, Eliane Mery, Yasmin A Mahmoud, Eman K Al-Azwani, Laurence Roger, Ruby Huang, Eva Jouve, Raphael Lis, Jean-Paul Thiery, Denis Querleu, Arash Rafii
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28561 (2011)
Ovarian cancer is the most deadly gynecological cancer. The high rate of mortality is due to the large tumor burden with extensive metastatic lesion of the abdominal cavity. Despite initial chemosensitivity and improved surgical procedures, abdominal
Externí odkaz:
https://doaj.org/article/1b35a7481b5f4ba18297acac980e14f6
Autor:
Lei Zhang, Yuqing Li, Lingli Zhou, Houhong Zhou, Liefu Ye, Tong Ou, Huaishan Hong, Shiwen Zheng, Ziyu Zhou, Kang Wu, Zeqin Yan, Jean Paul Thiery, Jun Cui, Song Wu
Publikováno v:
Cancer Research. :OF1-OF17
N6-Methyladenosine (m6A) is the most prevalent internal modification of mammalian mRNAs. Recent studies have shown that m6A methyltransferases METTL3 and METTL14 play important roles in urothelial bladder carcinoma (BLCA). To provide a more comprehen
Autor:
Win Lwin Thuya, Li Ren Kong, Nicholas L. Syn, Ling-Wen Ding, Esther Sok Hwee Cheow, Regina Tong Xin Wong, Tingting Wang, Robby Miguel Wen-Jing Goh, Hongyan Song, Migara K. Jayasinghe, Minh TN Le, Jian Cheng Hu, Wei-Peng Yong, Soo-Chin Lee, Andrea Li-Ann Wong, Gautam Sethi, Huynh The Hung, Paul Chi-Lui Ho, Jean-Paul Thiery, Siu Kwan Sze, Tiannan Guo, Ross A. Soo, Henry Yang, Yaw Chyn Lim, Lingzhi Wang, Boon-Cher Goh
Publikováno v:
Theranostics. 13:621-638