Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Jean‐Paul Pais de Barros"'
Autor:
Sarah Tarhini, Carla Crespo-Quiles, Emmanuelle Buhler, Louison Pineau, Emilie Pallesi-Pocachard, Solène Villain, Saswati Saha, Lucas Silvagnoli, Thomas Stamminger, Hervé Luche, Carlos Cardoso, Jean-Paul Pais de Barros, Nail Burnashev, Pierre Szepetowski, Sylvian Bauer
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background Congenital cytomegalovirus (CMV) infections represent one leading cause of human neurodevelopmental disorders. Despite their high prevalence and severity, no satisfactory therapy is available and pathophysiology remains elusive. T
Externí odkaz:
https://doaj.org/article/91dccd27ff4e43eca32f33b423e2d839
Autor:
Aleksandra Georgievski, Pierre-Simon Bellaye, Benjamin Tournier, Hélène Choubley, Jean-Paul Pais de Barros, Michaële Herbst, Arnaud Béduneau, Patrick Callier, Bertrand Collin, Frédérique Végran, Paola Ballerini, Carmen Garrido, Ronan Quéré
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-17 (2024)
Abstract We created valrubicin-loaded immunoliposomes (Val-ILs) using the antitumor prodrug valrubicin, a hydrophobic analog of daunorubicin. Being lipophilic, valrubicin readily incorporated Val-lLs that were loaded with specific antibodies. Val-ILs
Externí odkaz:
https://doaj.org/article/37e10694d8ae4fb1b128a2f9d144de83
Autor:
Petra P. Larsen, MD, Catherine Féart, PhD, Jean-Paul Pais de Barros, PhD, Laure Gayraud, MSc, Marie-Noëlle Delyfer, MD, PhD, Jean-François Korobelnik, MD, Cédric Schweitzer, MD, PhD, Cécile Delcourt, PhD
Publikováno v:
Ophthalmology Science, Vol 5, Iss 1, Pp 100610- (2025)
Purpose: Lipopolysaccharide (LPS)-type endotoxins are naturally found in the gut microbiota and there is emerging evidence linking gut microbiota and neuroinflammation leading to retinal neurodegeneration. Thinning of the retinal nerve fiber layer (R
Externí odkaz:
https://doaj.org/article/7c73dcb7568741199aa54bc3be1d0e70
Autor:
Maxime Nguyen, Alain Putot, David Masson, Yves Cottin, Thomas Gautier, Laura Tribouillard, Anne-Laure Rérole, Pierre-Grégoire Guinot, Maud Maza, Jean-Paul Pais de Barros, Valérie Deckert, Michel Farnier, Laurent Lagrost, Marianne Zeller
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
BackgroundThere is increasing evidence regarding the association between endotoxemia and the pathogenesis of atherosclerosis and myocardial infarction (MI). During the acute phase of MI, endotoxemia might increase inflammation and drive adverse cardi
Externí odkaz:
https://doaj.org/article/123c9002e7f048d9860e8dce45bf2147
Autor:
Louise Ménégaut, Aline Laubriet, Valentin Crespy, Damien Leleu, Thomas Pilot, Kevin Van Dongen, Jean-Paul Pais de Barros, Thomas Gautier, Jean-Michel Petit, Charles Thomas, Maxime Nguyen, Eric Steinmetz, David Masson
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-10 (2023)
Abstract Background Type 2 diabetes mellitus (T2DM) is a major global health issue and a significant risk factor for atherosclerosis. Atherosclerosis in T2DM patients has been associated with inflammation, insulin resistance, hyperglycemia, dyslipide
Externí odkaz:
https://doaj.org/article/0540cb8dd4e742f29c178ae284ca190f
Autor:
Samah Maaloul, Imen Ghzaiel, Maher Mahmoudi, Hédi Mighri, Vivien Pires, Anne Vejux, Lucie Martine, Jean-Paul Pais de Barros, Emmanuelle Prost-Camus, Fayçal Boughalleb, Gérard Lizard, Raoudha Abdellaoui
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0304021 (2024)
Milk thistle seed oil is still not a well-known edible oil. Silybum marianum (milk thistle), is present in several countries and is the only known representative of the genus Silybum. However, Silybum eburneum, which is an endemic plant in Spain, Ken
Externí odkaz:
https://doaj.org/article/357d207223bc46d2b8949b520108cbe5
Autor:
Trinh-Le-Vi Kieu, Léa Pierre, Valentin Derangère, Sabrina Perrey, Caroline Truntzer, Antoine Jalil, Sébastien Causse, Emma Groetz, Adélie Dumont, Laura Guyard, Laurent Arnould, Jean-Paul Pais de Barros, Lionel Apetoh, Cédric Rébé, Emeric Limagne, Tony Jourdan, Laurent Demizieux, David Masson, Charles Thomas, François Ghiringhelli, Mickaël Rialland
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-18 (2022)
Abstract Metastatic breast cancer cannot be cured, and alteration of fatty acid metabolism contributes to tumor progression and metastasis. Here, we were interested in the elongation of very long-chain fatty acids protein 5 (Elovl5) in breast cancer.
Externí odkaz:
https://doaj.org/article/e46e8fef42814a68866b78b5481c0414
Autor:
Aleksandra Georgievski, Anaïs Michel, Charles Thomas, Zandile Mlamla, Jean-Paul Pais de Barros, Stéphanie Lemaire-Ewing, Carmen Garrido, Ronan Quéré
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-13 (2022)
Abstract Patient-derived xenografted (PDX) models were generated through the transplantation of primary acute lymphoblastic leukemia (ALL) cells into immunodeficient NSG mice. We observed that ALL cells from mouse bone marrow (BM) produced extracellu
Externí odkaz:
https://doaj.org/article/5196439bbe924bf29d56120e283fd0d6
Autor:
Maxime Nguyen, Abderrahmane Bourredjem, Lionel Piroth, Bélaïd Bouhemad, Antoine Jalil, Gaetan Pallot, Naig Le Guern, Charles Thomas, Thomas Pilot, Victoria Bergas, Hélène Choubley, Jean-Pierre Quenot, Pierre-Emmanuel Charles, Laurent Lagrost, Valerie Deckert, Jean-Paul Pais de Barros, Pierre-Grégoire Guinot, David Masson, Christine Binquet, Thomas Gautier, Mathieu Blot, Lymphonie study group
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract COVID-19 pneumonia has specific features and outcomes that suggests a unique immunopathogenesis. Severe forms of COVID-19 appear to be more frequent in obese patients, but an association with metabolic disorders is not established. Here, we
Externí odkaz:
https://doaj.org/article/97f18805af9645668ad7756794ccc87c
Autor:
Rony Mshaik, John Simonet, Aleksandra Georgievski, Layla Jamal, Shaliha Bechoua, Paola Ballerini, Pierre-Simon Bellaye, Zandile Mlamla, Jean-Paul Pais de Barros, Audrey Geissler, Pierre-Jean Francin, François Girodon, Carmen Garrido, Ronan Quéré
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 3, Pp 1-15 (2021)
Abstract T-cell and B-cell acute lymphoblastic leukemias (T-ALL, B-ALL) are aggressive hematological malignancies characterized by an accumulation of immature T- or B-cells. Although patient outcomes have improved, novel targeted therapies are needed
Externí odkaz:
https://doaj.org/article/442319e688b54fc3b235c0188e43bb65