Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Jean‐Paul Pais‐De‐Barros"'
Autor:
Damien Denimal, Sarah Béland-Bonenfant, Jean-Paul Pais-de-Barros, Alexia Rouland, Benjamin Bouillet, Laurence Duvillard, Bruno Vergès, Jean-Michel Petit
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-12 (2023)
Abstract Background There is growing evidence that ceramides play a significant role in the onset and progression of non-alcoholic fatty liver disease (NAFLD), a highly prevalent condition in patients with type 2 diabetes associated with hepatic and
Externí odkaz:
https://doaj.org/article/e7f42cb3eb12415eb0e57907a81964f7
Autor:
Sophie Hecquet, Perle Totoson, Hélène Martin, Marie-Paule Algros, Philippe Saas, Jean-Paul Pais-de-Barros, Alban Atchon, Benoît Valot, Didier Hocquet, Maude Tournier, Clément Prati, Daniel Wendling, Céline Demougeot, Frank Verhoeven
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-12 (2023)
Abstract Background Intestinal inflammation, dysbiosis, intestinal permeability (IP), and bacterial translocation (BT) have been identified in patients with spondyloarthritis but the time at which they appear and their contribution to the pathogenesi
Externí odkaz:
https://doaj.org/article/4620a1ef7cef42dab135bd4b38a2404a
Autor:
Damien Denimal, Victoria Bergas, Jean-Paul Pais-de-Barros, Isabelle Simoneau, Laurent Demizieux, Patricia Passilly-Degrace, Benjamin Bouillet, Jean-Michel Petit, Alexia Rouland, Amandine Bataille, Laurence Duvillard, Bruno Vergès
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-12 (2023)
Abstract Background Emerging evidence supports that dihydroceramides (DhCer) and ceramides (Cer) contribute to the pathophysiology of insulin resistance and liver steatosis, and that their circulating concentrations are independently associated with
Externí odkaz:
https://doaj.org/article/c20c51d1ec374a4897f888e61afcf59a
Autor:
Mohammed I. Y. Elmallah, Pablo Ortega‐Deballon, Laure Hermite, Jean‐Paul Pais‐De‐Barros, Jessica Gobbo, Carmen Garrido
Publikováno v:
Molecular Oncology, Vol 16, Iss 14, Pp 2710-2718 (2022)
Strong evidence suggests that differences in the molecular composition of lipids in exosomes depend on the cell type and has an influence on cancer initiation and progression. Here, we analyzed by liquid chromatography–mass spectrometry (LC‐MS) t
Externí odkaz:
https://doaj.org/article/f65ea47bc0d44a5a92423e64fcd540a2
Autor:
Trinh-Le-Vi Kieu, Léa Pierre, Valentin Derangère, Sabrina Perrey, Caroline Truntzer, Antoine Jalil, Sébastien Causse, Emma Groetz, Adélie Dumont, Laura Guyard, Laurent Arnould, Jean-Paul Pais de Barros, Lionel Apetoh, Cédric Rébé, Emeric Limagne, Tony Jourdan, Laurent Demizieux, David Masson, Charles Thomas, François Ghiringhelli, Mickaël Rialland
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-18 (2022)
Abstract Metastatic breast cancer cannot be cured, and alteration of fatty acid metabolism contributes to tumor progression and metastasis. Here, we were interested in the elongation of very long-chain fatty acids protein 5 (Elovl5) in breast cancer.
Externí odkaz:
https://doaj.org/article/e46e8fef42814a68866b78b5481c0414
Autor:
Mathieu Blot, Marine Jacquier, Ludwig-Serge Aho Glele, Guillaume Beltramo, Maxime Nguyen, Philippe Bonniaud, Sebastien Prin, Pascal Andreu, Belaid Bouhemad, Jean-Baptiste Bour, Christine Binquet, Lionel Piroth, Jean-Paul Pais de Barros, David Masson, Jean-Pierre Quenot, Pierre-Emmanuel Charles, Pneumochondrie study group
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-15 (2020)
Abstract Background COVID-19-related ARDS has unique features when compared with ARDS from other origins, suggesting a distinctive inflammatory pathogenesis. Data regarding the host response within the lung are sparse. The objective is to compare alv
Externí odkaz:
https://doaj.org/article/9317c93fd0e747da8c1bcba552f1ffd7
Autor:
Louise Ménégaut, Charles Thomas, Antoine Jalil, Jean Baptiste Julla, Charlène Magnani, Adam Ceroi, Louise Basmaciyan, Adélie Dumont, Wilfried Le Goff, Mano Joseph Mathew, Cédric Rébé, Valentin Dérangère, Aline Laubriet, Valentin Crespy, Jean-Paul Pais de Barros, Eric Steinmetz, Nicolas Venteclef, Philippe Saas, Laurent Lagrost, David Masson
Publikováno v:
Cell Reports, Vol 31, Iss 7, Pp - (2020)
Summary: Low-grade inflammation is constitutive of atherosclerosis, and anti-inflammatory therapy inhibiting interleukin-1β (IL-1β) reduces the rate of cardiovascular events. While cholesterol accumulation in atheroma plaque and macrophages is a ma
Externí odkaz:
https://doaj.org/article/3db0334021a940558885f0366630bc79
Autor:
Lorène J. Lebrun, Kaatje Lenaerts, Dorien Kiers, Jean-Paul Pais de Barros, Naig Le Guern, Jiri Plesnik, Charles Thomas, Thibaut Bourgeois, Cornelis H.C. Dejong, Matthijs Kox, Inca H.R. Hundscheid, Naim Akhtar Khan, Stéphane Mandard, Valérie Deckert, Peter Pickkers, Daniel J. Drucker, Laurent Lagrost, Jacques Grober
Publikováno v:
Cell Reports, Vol 21, Iss 5, Pp 1160-1168 (2017)
Summary: Glucagon-like peptide 1 (GLP-1) is a hormone released from enteroendocrine L cells. Although first described as a glucoregulatory incretin hormone, GLP-1 also suppresses inflammation and promotes mucosal integrity. Here, we demonstrate that
Externí odkaz:
https://doaj.org/article/54c442ddf2554e8d93b3af382d5f41cd
Autor:
Mayssa Albouery, Bénédicte Buteau, Stéphane Grégoire, Claire Cherbuy, Jean-Paul Pais de Barros, Lucy Martine, Florian Chain, Stéphanie Cabaret, Olivier Berdeaux, Alain M. Bron, Niyazi Acar, Philippe Langella, Marie-Agnès Bringer
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2020)
Understanding the molecular mechanisms underlying the changes observed during aging is a prerequisite to design strategies to prevent age-related diseases. Aging is associated with metabolic changes, including alteration in the brain lipid metabolism
Externí odkaz:
https://doaj.org/article/eb39cad8166e479d950499918aa01f17
Autor:
Clémence Carron, Jean-Paul Pais de Barros, Emilie Gaiffe, Valérie Deckert, Hanane Adda-Rezig, Caroline Roubiou, Caroline Laheurte, David Masson, Dominique Simula-Faivre, Pascale Louvat, Bruno Moulin, Luc Frimat, Philippe Rieu, Christiane Mousson, Antoine Durrbach, Anne-Elisabeth Heng, Philippe Saas, Didier Ducloux, Laurent Lagrost, Jamal Bamoulid
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Chronic inflammation in end-stage renal disease (ESRD) is partly attributed to gut bacterial translocation (GBT) due to loss of intestinal epithelium integrity. Increased levels of circulating lipopolysaccharide (LPS) –a surrogate marker of GBT–
Externí odkaz:
https://doaj.org/article/f055bcfae2a04b4c96521fff2e3437c9