Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Jean‐Paul G. Vonsattel"'
Autor:
Phyllis L. Faust, Morgan McCreary, Jessica B. Musacchio, Sheng‐Han Kuo, Jean‐Paul G. Vonsattel, Elan D. Louis
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 6, Pp 1514-1525 (2024)
Abstract Objective Essential tremor is among the most prevalent neurological diseases. Diagnosis is based entirely on neurological evaluation. Historically, there were few postmortem brain studies, hindering attempts to develop pathologically based c
Externí odkaz:
https://doaj.org/article/5353d20904244e67b26866e99499ea9e
Autor:
Philippe Gosset, Alexander Maxan, Melanie Alpaugh, Ludivine Breger, Benjamin Dehay, Zhu Tao, Zhang Ling, Chuan Qin, Giulia Cisbani, Nadia Fortin, Jean-Paul G. Vonsattel, Steve Lacroix, Abid Oueslati, Erwan Bezard, Francesca Cicchetti
Publikováno v:
Neurobiology of Disease, Vol 141, Iss , Pp 104941- (2020)
In recent years, substantial evidence has emerged to suggest that spreading of pathological proteins contributes to disease pathology in numerous neurodegenerative disorders. Work from our laboratory and others have shown that, despite its strictly g
Externí odkaz:
https://doaj.org/article/ce39361aa4fd446ead26ea49a70374d5
Publikováno v:
Tremor and Other Hyperkinetic Movements, Vol 3 (2013)
Background:The phenomenology of tremor is broad and its classification is complicated. Furthermore, the full range of tremor phenomenology with respect to specific neurological and neurodegenerative diseases has not been fully elaborated. Case Report
Externí odkaz:
https://doaj.org/article/b9b9e05d67004004a439fff2bd724dd4
Publikováno v:
Tremor and Other Hyperkinetic Movements, Vol 2 (2012)
Background: Clinical studies have implicated the cerebellum in the pathogenesis of essential tremor (ET), and recent postmortem studies have identified structural changes in the ET cerebellum. While the basal ganglia have traditionally been implicate
Externí odkaz:
https://doaj.org/article/dbc86aa2bcd04ef391347ecd8ceb2066
Autor:
Marta Olah, Vilas Menon, Naomi Habib, Mariko F. Taga, Yiyi Ma, Christina J. Yung, Maria Cimpean, Anthony Khairallah, Guillermo Coronas-Samano, Roman Sankowski, Dominic Grün, Alexandra A. Kroshilina, Danielle Dionne, Rani A. Sarkis, Garth R. Cosgrove, Jeffrey Helgager, Jeffrey A. Golden, Page B. Pennell, Marco Prinz, Jean Paul G. Vonsattel, Andrew F. Teich, Julie A. Schneider, David A. Bennett, Aviv Regev, Wassim Elyaman, Elizabeth M. Bradshaw, Philip L. De Jager
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Imbalance of microglial phenotypes in the aging brain might underlie their involvement in late onset neurodegenerative diseases. Here we report the population structure of microglia in the aged human brain and the reduction of a particular microglia
Externí odkaz:
https://doaj.org/article/70f5aedb5f20425e97be8410947e4a81
Autor:
Peng Liu, Benjamin R. Smith, Eric S. Huang, Abhishek Mahesh, Jean Paul G. Vonsattel, Ashley J. Petersen, Rocio Gomez-Pastor, Karen H. Ashe
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Huntington’s disease (HD) is a progressive neurodegenerative disease. Involuntary movements, cognitive impairment and psychiatric disturbance are the major clinical manifestations, and gradual atrophy and selective neuronal loss in the str
Externí odkaz:
https://doaj.org/article/bfeaca9ab7f04f0397abd24da55d5320
Autor:
Elan D Louis, Daniella Iglesias-Hernandez, Nora C Hernandez, Xena Flowers, Sheng-Han Kuo, Jean Paul G Vonsattel, Phyllis L Faust
Publikováno v:
Journal of neuropathology and experimental neurology. 81(10)
The Essential Tremor Centralized Brain Repository is the largest repository of prospectively collected essential tremor (ET) brains (n = 231). Hence, we are uniquely poised to address several questions: What proportion of ET cases has Lewy pathology
Autor:
Elan D. Louis, Regina T. Martuscello, John T. Gionco, Whitney G. Hartstone, Jessica B. Musacchio, Marisa Portenti, Morgan McCreary, Sheng-Han Kuo, Jean-Paul G. Vonsattel, Phyllis L. Faust
Publikováno v:
Acta Neuropathologica. 145:265-283
Autor:
Elan D, Louis, Regina T, Martuscello, John T, Gionco, Whitney G, Hartstone, Jessica B, Musacchio, Marisa, Portenti, Morgan, McCreary, Sheng-Han, Kuo, Jean-Paul G, Vonsattel, Phyllis L, Faust
Publikováno v:
Acta neuropathologica.
In recent years, numerous morphologic changes have been identified in the essential tremor (ET) cerebellar cortex, distinguishing ET from control brains. These findings have not been fully contextualized within a broader degenerative disease spectrum
Autor:
Jennifer J. Manly, Jeffrey L. Dage, Dolly Reyes-Dumeyer, Andrew F. Teich, Jean Paul G. Vonsattel, Yaakov Stern, Richard Mayeux, Danurys Sanchez, Adam M. Brickman, Nicholas K. Proctor, Rafael Lantigua, Patrick J. Lao, David C. Airey, Lawrence S. Honig
Publikováno v:
Alzheimer's & Dementia
Introduction Blood‐based Alzheimer's disease (AD) biomarkers provide opportunities for community studies and across ethnic groups. We investigated blood biomarker concentrations in the Washington Heights‐Inwood Columbia Aging Project (WHICAP), a