Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jean‐Noel Freund"'
Autor:
Reine El Omar, Naoill Abdellaoui, Safiatou T. Coulibaly, Laura Fontenille, François Lanza, Christian Gachet, Jean-Noel Freund, Matteo Negroni, Karima Kissa, Manuela Tavian
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-10 (2024)
Abstract Zebrafish is widely adopted as a grafting model for studying human development and diseases. Current zebrafish xenotransplantations are performed using embryo recipients, as the adaptive immune system, responsible for host versus graft rejec
Externí odkaz:
https://doaj.org/article/f6918c37b1294da69647987e0d15f79e
Autor:
Maria Virginia Giolito, Théo La Rosa, Diana Farhat, Serguei Bodoirat, Gabriela D. A. Guardia, Claire Domon‐Dell, Pedro A. F. Galante, Jean‐Noel Freund, Michelina Plateroti
Publikováno v:
Molecular Oncology, Vol 16, Iss 22, Pp 3975-3993 (2022)
The THRA gene, encoding the thyroid hormone nuclear receptor TRα1, is expressed in an increasing gradient at the bottom of intestinal crypts, overlapping with high Wnt and Notch activities. Importantly, THRA is upregulated in colorectal cancers, par
Externí odkaz:
https://doaj.org/article/9088fcb36d304e73a6be70f48360ab38
Autor:
Emilie Bersuder, Chloe Terciolo, Mathilde Lechevrel, Elisabeth Martin, Celine Quesnelle, Jean-Noel Freund, Jean-Marie Reimund, Isabelle Gross
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 146, Iss , Pp 112543- (2022)
Chronic inflammation associated with intestinal architecture and barrier disruption puts patients with inflammatory bowel disease (IBD) at increased risk of developing colorectal cancer (CRC). Widely used to reduce flares of intestinal inflammation,
Externí odkaz:
https://doaj.org/article/bada4523ca1a461cafd72432d59af3e8
Autor:
Xavier Tréton, Eric Pedruzzi, Cécile Guichard, Yannick Ladeiro, Shirin Sedghi, Mélissa Vallée, Neike Fernandez, Emilie Bruyère, Paul-Louis Woerther, Robert Ducroc, Nicolas Montcuquet, Jean-Noel Freund, Isabelle Van Seuningen, Frédérick Barreau, Assiya Marah, Jean-Pierre Hugot, Dominique Cazals-Hatem, Yoram Bouhnik, Fanny Daniel, Eric Ogier-Denis
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101669 (2014)
Ulcerative colitis (UC) is a chronic inflammatory bowel disease affecting the rectum which progressively extents. Its etiology remains unknown and the number of treatments available is limited. Studies of UC patients have identified an unbalanced end
Externí odkaz:
https://doaj.org/article/785d897e7a834d739ab99c7e3081bc4c
Autor:
Igor Martianov, Emilie Cler, Isabelle Duluc, Serge Vicaire, Muriel Philipps, Jean-Noel Freund, Irwin Davidson
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87365 (2014)
Collagen 6A3 (Col6a3), a component of extracellular matrix, is often up-regulated in tumours and is believed to play a pro-oncogenic role. However the mechanisms of its tumorigenic activity are poorly understood. We show here that Col6a3 is highly ex
Externí odkaz:
https://doaj.org/article/5e418e1986b342ceb0908dc53b9c5034
Autor:
Morgane Rabineau, Leyla Kocgozlu, Denis Dujardin, Bernard Senger, Youssef Haikel, Jean-Claude Voegel, Jean-Noel Freund, Pierre Schaaf, Philippe Lavalle, Dominique Vautier
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78468 (2013)
In colon cancer, a highly aggressive disease, progression through the malignant sequence is accompanied by increasingly numerous chromosomal rearrangements. To colonize target organs, invasive cells cross several tissues of various elastic moduli. Wh
Externí odkaz:
https://doaj.org/article/4080e90125974780a0e4377755a02c6b
Autor:
Laurent Pons, Shyue-Fang Battaglia-Hsu, Carlos Enrique Orozco-Barrios, Sandrine Ortiou, Celine Chery, Jean-Marc Alberto, Martha Ligia Arango-Rodriguez, Dominique Dumas, Daniel Martinez-Fong, Jean-Noel Freund, Jean-Louis Gueant
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6325 (2009)
BACKGROUND: Oleosin is a plant protein localized to lipid droplets and endoplasmic reticulum of plant cells. Our idea was to use it to target functional secretory proteins of interest to the cytosolic side of the endoplasmic reticulum of mammalian ce
Externí odkaz:
https://doaj.org/article/b6be51eaf05642b1b4ff62c64eaa6e26
Autor:
Susanna Säisä-Borreill, Guillaume Davidson, Thomas Kleiber, Andréa Thevenot, Elisabeth Martin, Stanislas Mondot, Hervé Blottière, Alexandra Helleux, Gabrielle Mengus, Michelina Plateroti, Isabelle Duluc, Irwin Davidson, Jean-Noel Freund
Publikováno v:
Cell Death & Differentiation. 30:839-853
Taf4 (TATA-box binding protein-associated factor 4) is a subunit of the general transcription factor TFIID, a component of the RNA polymerase II pre-initiation complex that interacts with tissue-specific transcription factors to regulate gene express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c965043d0c8db0f0fdcb574dbdb1e58e
https://doi.org/10.1038/s41418-022-01109-6
https://doi.org/10.1038/s41418-022-01109-6
Autor:
Michelina Plateroti, Christelle de la Fouchardiere, Jean-Noel Freund, Luiz O. Penalva, Pedro A.F. Galante, Jérôme Guitton, Pierre Laurent-Puig, Clémentine Le Nevé, Camilla Pilati, Christelle Machon, Gabriela D.A. Guardia, Gaspard Delpouve, Catherine Jamard, Carla Frau
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39582957fd9dbd0d00492d263c0a15a2
https://doi.org/10.1158/0008-5472.22426726.v1
https://doi.org/10.1158/0008-5472.22426726.v1
Autor:
Michelina Plateroti, Christelle de la Fouchardiere, Jean-Noel Freund, Luiz O. Penalva, Pedro A.F. Galante, Jérôme Guitton, Pierre Laurent-Puig, Clémentine Le Nevé, Camilla Pilati, Christelle Machon, Gabriela D.A. Guardia, Gaspard Delpouve, Catherine Jamard, Carla Frau
Intestinal crypts are composed of heterogeneous and highly plastic cell populations. Lgr5high-stem cells (SC) are responsible for homeostatic renewal, but other cells can revert to an SC-like phenotype to maintain epithelial integrity. Despite their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d592a80037b7c2b03fef3bb70f34e0a
https://doi.org/10.1158/0008-5472.c.6512431.v1
https://doi.org/10.1158/0008-5472.c.6512431.v1