Zobrazeno 1 - 10
of 351
pro vyhledávání: '"Jean‐Jacques Vasseur"'
Autor:
Sébastien Relier, Julie Ripoll, Hélène Guillorit, Amandine Amalric, Cyrinne Achour, Florence Boissière, Jérôme Vialaret, Aurore Attina, Françoise Debart, Armelle Choquet, Françoise Macari, Virginie Marchand, Yuri Motorin, Emmanuelle Samalin, Jean-Jacques Vasseur, Julie Pannequin, Francesca Aguilo, Evelyne Lopez-Crapez, Christophe Hirtz, Eric Rivals, Amandine Bastide, Alexandre David
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The demethylase FTO was shown to remove on N6-methyladenosine (m6A) and N6, 2’-O-dimethyladenosine (m6Am) modifications on RNAs. Here the authors show that FTO impedes cancer stem cell-like abilities in colorectal cancer cells through its m6Am deme
Externí odkaz:
https://doaj.org/article/9446244d632a4b05a389d98461a70dd7
Autor:
Priscila Sutto-Ortiz, Sergey Tcherniuk, Nina Ysebaert, Pravien Abeywickrema, Mathieu Noël, Alice Decombe, Françoise Debart, Jean-Jacques Vasseur, Bruno Canard, Dirk Roymans, Peter Rigaux, Jean-François Eléouët, Etienne Decroly
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009562 (2021)
Respiratory syncytial virus (RSV) is a negative sense single-stranded RNA virus and one of the main causes of severe lower respiratory tract infections in infants and young children. RSV RNA replication/transcription and capping are ensured by the vi
Externí odkaz:
https://doaj.org/article/70047fcf48b749b8834adc4f16a949f7
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 436-469 (2018)
Oligonucleotides (ONs) have been envisaged for therapeutic applications for more than thirty years. However, their broad use requires overcoming several hurdles such as instability in biological fluids, low cell penetration, limited tissue distributi
Externí odkaz:
https://doaj.org/article/940694118b764537a14dbeff710a2beb
Autor:
Fanny Leon, Elena Pinchon, Nevzat Temurok, François Morvan, Jean-Jacques Vasseur, Martine Clot, Vincent Foulongne, Jean-François Cantaloube, Philippe Vande Perre, Jean-Pierre Molès, Aurélien Daynès, Chantal Fournier-Wirth
Publikováno v:
Microorganisms, Vol 9, Iss 4, p 674 (2021)
Arbovirus diagnostics on blood from donors and travelers returning from endemic areas is increasingly important for better patient management and epidemiological surveillance. We developed a flexible approach based on a magnetic field-enhanced agglut
Externí odkaz:
https://doaj.org/article/ed74018ccc3d45e49927525f8e960438
Autor:
Nathan Meyer, Jean-Marc Janot, Mathilde Lepoitevin, Michaël Smietana, Jean-Jacques Vasseur, Joan Torrent, Sébastien Balme
Publikováno v:
Biosensors, Vol 10, Iss 10, p 140 (2020)
Single nanopore is a powerful platform to detect, discriminate and identify biomacromolecules. Among the different devices, the conical nanopores obtained by the track-etched technique on a polymer film are stable and easy to functionalize. However,
Externí odkaz:
https://doaj.org/article/a347359b6329482ea08399c6052e0f40
Autor:
Florian Gauthier, Jean-Rémi Bertrand, Jean-Jacques Vasseur, Christelle Dupouy, Françoise Debart
Publikováno v:
Molecules, Vol 25, Iss 11, p 2714 (2020)
Co-delivery systems of siRNA and chemotherapeutic drugs have been developed as an attractive strategy to optimize the efficacy of chemotherapy towards cancer cells with multidrug resistance. In these typical systems, siRNAs are usually associated to
Externí odkaz:
https://doaj.org/article/a3fee217948b4875be220b3f2d45c708
Autor:
Ana Tamarkin-Ben-Harush, Jean-Jacques Vasseur, Françoise Debart, Igor Ulitsky, Rivka Dikstein
Publikováno v:
eLife, Vol 6 (2017)
Transcription start-site (TSS) selection and alternative promoter (AP) usage contribute to gene expression complexity but little is known about their impact on translation. Here we performed TSS mapping of the translatome following energy stress. Ass
Externí odkaz:
https://doaj.org/article/7653f178f3df4d33b63599ef37cdc108
Autor:
Lucie Dupin, Mathieu Noël, Silvère Bonnet, Albert Meyer, Thomas Géhin, Ludovic Bastide, Mialy Randriantsoa, Eliane Souteyrand, Claire Cottin, Gérard Vergoten, Jean-Jacques Vasseur, François Morvan, Yann Chevolot, Benoît Darblade
Publikováno v:
Molecules, Vol 23, Iss 12, p 3073 (2018)
The Gram negative bacterium Pseudomonas aeruginosa (PA) is an opportunistic bacterium that causes severe and chronic infection of immune-depressed patients. It has the ability to form a biofilm that gives a selective advantage to the bacteria with re
Externí odkaz:
https://doaj.org/article/b52e645cabb248778999716fa2cf23d4
Autor:
Diallo Traoré, Elisa Biecher, Manon Mallet, Sonia Rouanet, Dr. Jean‐Jacques Vasseur, Prof. Michael Smietana, Dr. Christelle Dupouy
Publikováno v:
ChemistryOpen, Vol 13, Iss 8, Pp n/a-n/a (2024)
Abstract We recently reported the properties of RNA hairpins constrained by a dimethylene (DME) disulfide (S−S) linker incorporated between two adjacent nucleosides in the loop and showed that this linker locked the hairpin conformation thus distur
Externí odkaz:
https://doaj.org/article/bb0e8db1315b4704969c64fe26eb9c19
Autor:
Barbara Selisko, Supanee Potisopon, Rym Agred, Stéphane Priet, Isabelle Varlet, Yann Thillier, Corinne Sallamand, Françoise Debart, Jean-Jacques Vasseur, Bruno Canard
Publikováno v:
PLoS Pathogens, Vol 8, Iss 9, p e1002912 (2012)
The dengue virus (DV) is an important human pathogen from the Flavivirus genus, whose genome- and antigenome RNAs start with the strictly conserved sequence pppAG. The RNA-dependent RNA polymerase (RdRp), a product of the NS5 gene, initiates RNA synt
Externí odkaz:
https://doaj.org/article/76c3082d65184f379e4173d555b6083d