Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jean‐François Paré"'
Autor:
Megan M. Sperry, Richard Novak, Vishal Keshari, Alexandre L. M. Dinis, Mark J. Cartwright, Diogo M. Camacho, Jean‐François Paré, Michael Super, Michael Levin, Donald E. Ingber
Publikováno v:
Advanced Science, Vol 9, Iss 26, Pp n/a-n/a (2022)
Abstract Current therapeutic strategies against bacterial infections focus on reduction of pathogen load using antibiotics; however, stimulation of host tolerance to infection in the presence of pathogens might offer an alternative approach. Computat
Externí odkaz:
https://doaj.org/article/b3569f885c82444d82a5bf6c27edcae0
Autor:
Vaibhav P. Pai, Valerie Willocq, Emily J. Pitcairn, Joan M. Lemire, Jean-François Paré, Nian-Qing Shi, Kelly A. McLaughlin, Michael Levin
Publikováno v:
Biology Open, Vol 6, Iss 10, Pp 1445-1457 (2017)
Laterality is a basic characteristic of all life forms, from single cell organisms to complex plants and animals. For many metazoans, consistent left-right asymmetric patterning is essential for the correct anatomy of internal organs, such as the hea
Externí odkaz:
https://doaj.org/article/689a0e604839463a8dcd34890ee2ff83
Publikováno v:
npj Regenerative Medicine, Vol 2, Iss 1, Pp 1-15 (2017)
Sparking immunity: Bioelectric signaling modulates immunity and regeneration Bioelectrical signaling in the African clawed frog modulates both resistance to infection and tail regeneration. Michael Levin at Tufts University in Massachusetts, USA, and
Externí odkaz:
https://doaj.org/article/02efc15f62274d419645979beec788cf
Autor:
Lori Minassian, Daniel Sanwalka, Jean-François Paré, Shannyn Macdonald-Goodfellow, R. Liam Sutherland, Abdi Ghaffari, Chelsea L. Margerum, Madhuri Koti, Andrew W.B. Craig, Tiziana Cotechini, D. Robert Siemens, Edmond Chan, Charles H. Graham
BackgroundWhile the Programmed Death 1/Programmed Death Ligand 1 (PD-1/PD-L1) immune checkpoint is an important mechanism of immune evasion in cancer, recent studies have shown that it can also lead to resistance to chemotherapy in cancer cells via r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b2f1520b79c4e047523f68f7ee90f50
https://doi.org/10.1101/2023.01.17.524124
https://doi.org/10.1101/2023.01.17.524124
Autor:
Alina Fischer, Sophia K. Jannetty, Celia Herrera-Rincon, Michael Levin, Richard M. Novak, Christina Harrison, Christopher J. Martyniuk, Alexandre L. M. Dinis, Jean-François Paré, Vishal Keshari
Publikováno v:
npj Regenerative Medicine, Vol 5, Iss 1, Pp 1-18 (2020)
NPJ Regenerative Medicine
NPJ Regenerative Medicine
Infections have numerous effects on the brain. However, possible roles of the brain in protecting against infection, and the developmental origin and role of brain signaling in immune response, are largely unknown. We exploited a unique Xenopus embry
Autor:
Dinis Alm, Mark Cartwright, Michael Levin, Keshari, Diogo M. Camacho, Sperry Mm, Jean-François Paré, Michael Super, Donald E. Ingber, Richard M. Novak
Current therapeutic strategies against bacterial infections focus on reduction of pathogen load through antibiotics; however, stimulation of host tolerance to infection might offer an alternative approach. Here we used computational transcriptomics a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e413cce8ea2793088d89b24dbd783c5c
https://doi.org/10.1101/2021.09.30.462576
https://doi.org/10.1101/2021.09.30.462576
Autor:
Charles C.T. Hindmarch, Jean-François Paré, Madhuri Koti, Diana Marginean, Wilma M. Hopman, D. Robert Siemens, Abdi Ghaffari, Charles H. Graham, Tiziana Cotechini, Stephen Chenard
Publikováno v:
Canadian Urological Association Journal. 15
Introduction: While studies suggest that innate immune memory acquired by circulating monocytes may mediate the benefit of bacillus Calmette-Guérin (BCG) in the treatment of patients with high-risk non-muscle-invasive bladder cancer (NMIBC), prospec
Autor:
Jean-François Paré, Ivraym B. Barsoum, Harrison Loh, Judy Kim, D. Robert Siemens, Charles H. Graham
Publikováno v:
Bioscience Reports
A key mechanism mediating cellular adaptive responses to hypoxia involves the activity of hypoxia-inducible factor 1 (HIF-1), a transcription factor composed of HIF-1α, and HIF-1β subunits. The classical mechanism of regulation of HIF-1 activity in
Autor:
Valerie Willocq, Nian-Qing Shi, Kelly A. McLaughlin, Jean-François Paré, Emily J. Pitcairn, Joan M. Lemire, Vaibhav P. Pai, Michael Levin
Publikováno v:
Biology Open, Vol 6, Iss 10, Pp 1445-1457 (2017)
Biology Open
Biology Open
Laterality is a basic characteristic of all life forms, from single cell organisms to complex plants and animals. For many metazoans, consistent left-right asymmetric patterning is essential for the correct anatomy of internal organs, such as the hea
Publikováno v:
npj Regenerative Medicine, Vol 2, Iss 1, Pp 1-15 (2017)
Two key inputs that regulate regeneration are the function of the immune system, and spatial gradients of transmembrane potential (V mem). Endogenous bioelectric signaling in somatic tissues during regenerative patterning is beginning to be understoo