Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Jean‐François Mosnier"'
Autor:
Astrid Imbert, Pierre-Jean Gavlovsky, Jean-Paul Judor, Edouard Bardou-Jacquet, Laure Elkrief, Adrien Lannes, Christine Silvain, Mathieu Schnee, Florence Tanne, Caroline Chevalier, Fabienne Vavasseur, Marion Khaldi, Sophie Brouard, Jean-François Mosnier, Jérôme Gournay, Sophie Conchon, Amédée Renand
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Relapse after immunosuppression (IS) treatment withdrawal is frequent in patients with Autoimmune Hepatitis (AIH), and non-invasive biomarkers predictive of this risk are lacking. We assessed the frequency of circulating T cell subsets as po
Externí odkaz:
https://doaj.org/article/f249c91e0f4045b49ea2ccb0dae5c652
Autor:
Malgorzata Osmola, Caroline Hemont, Nicolas Chapelle, Marie-Anne Vibet, David Tougeron, Driffa Moussata, Dominique Lamarque, Edith Bigot-Corbel, Damien Masson, Justine Blin, Maxime Leroy, Regis Josien, Jean-François Mosnier, Jérôme Martin, Tamara Matysiak-Budnik
Publikováno v:
Diagnostics, Vol 13, Iss 9, p 1599 (2023)
Despite a global decrease, gastric cancer (GC) incidence appears to be increasing recently in young, particularly female, patients. The causal mechanism for this “new” type of GC is unknown, but a role for autoimmunity is suggested. A cascade of
Externí odkaz:
https://doaj.org/article/81ce2854ed4744fdb63524eb169ac7cd
Autor:
Anne Dariel, Lucie Grynberg, Marie Auger, Chloé Lefèvre, Tony Durand, Philippe Aubert, Catherine Le Berre-Scoul, Aurélien Venara, Etienne Suply, Marc-David Leclair, Philine de Vries, Guillaume Levard, Benoit Parmentier, Guillaume Podevin, Françoise Schmitt, Véronique Couvrat, Sabine Irtan, Erik Hervieux, Thierry Villemagne, Hubert Lardy, Carmen Capito, Cécile Muller, Sabine Sarnacki, Jean-François Mosnier, Louise Galmiche, Pascal Derkinderen, Hélène Boudin, Charlène Brochard, Michel Neunlist
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract In Hirschsprung’s disease (HSCR), postoperative course remains unpredictable. Our aim was to define predictive factors of the main postoperative complications: obstructive symptoms (OS) and Hirschsprung-associated enterocolitis (HAEC). In
Externí odkaz:
https://doaj.org/article/3110da24af8843d099fb67bca2e44e21
Autor:
Marie Denis Musquer, Nicolas Jouand, Morgane Pere, Juliette Eugène Lamer, Stéphane Bézieau, Tamara Matysiak, Roger Faroux, François-Xavier Caroli Bosc, Marie-Christine Rousselet, François Leclair, Jean-François Mosnier, Claire Toquet, Nadine Gervois, Céline Bossard
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Antibody-dependent cellular cytotoxicity (ADCC) in the anti-tumor effect of cetuximab in metastatic colorectal cancer (mCRC) is only based on the impact of FcγRIIIA (CD16) polymorphisms as predictive of therapeutic response. However, nature, density
Externí odkaz:
https://doaj.org/article/4c3b75f4fa8a466db1a90307b95f7010
Autor:
Nicolas Chapelle, Malgorzata Osmola, Jérôme Martin, Justine Blin, Maxime Leroy, Iva Jirka, Driffa Moussata, Dominique Lamarque, Raphael Olivier, David Tougeron, Anne Hay-Lombardie, Edith Bigot-Corbel, Damien Masson, Jean-François Mosnier, Tamara Matysiak-Budnik
Publikováno v:
Diagnostics, Vol 12, Iss 3, p 695 (2022)
Background: Analysis of serum biomarkers for the assessment of atrophic gastritis (AG), a gastric precancerous lesion, is of growing interest for identification of patients at increased risk of gastric cancer. The aim was to analyze the diagnostic pe
Externí odkaz:
https://doaj.org/article/4f101a01935e44309452a27bd09d467c
Autor:
Amédée Renand, Sarah Habes, Jean‐François Mosnier, Hélène Aublé, Jean‐Paul Judor, Nicolas Vince, Philippe Hulin, Steven Nedellec, Sylvie Métairie, Isabelle Archambeaud, Sophie Brouard, Jérôme Gournay, Sophie Conchon
Publikováno v:
Hepatology Communications, Vol 2, Iss 8, Pp 972-985 (2018)
Autoimmune hepatitis (AIH) is a rare disease characterized by an immune attack of the liver. This study consists of a comprehensive analysis of immune alterations related to AIH at diagnosis, and during remission phase under treatment. A total of 37
Externí odkaz:
https://doaj.org/article/907f77c222954d06b8db5354f2a44e88
Autor:
Eva Ott, Linda Bilonda, Delphine Dansette, Cécile Deleine, Emilie Duchalais, Juliette Podevin, Christelle Volteau, Jaafar Bennouna, Yann Touchefeu, Pierre Fourquier, Wassila El Alami Thomas, Jérome Chetritt, Stéphane Bezieau, Marc Denis, Claire Toquet, Jean-François Mosnier, Anne Jarry, Céline Bossard
Publikováno v:
OncoImmunology, Vol 8, Iss 4 (2019)
Purpose: The recent success of anti-PD1 antibody in metastatic colorectal cancer (CRC) patients with microsatellite instability (MSI), known to be associated with an upregulated Th1/Tc1 gene signature, provides new promising therapeutic strategies. H
Externí odkaz:
https://doaj.org/article/b6672e6a5fb046ef950dbefa88542634
Autor:
Frédérique Souazé, Chantal Bou-Hanna, Christine Kandel, François Leclair, Julie Devallière, Béatrice Charreau, Stéphane Bézieau, Jean-François Mosnier, Christian L Laboisse
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55904 (2013)
Hath1, a bHLH transcription factor negatively regulated by the γ-secretase-dependent Notch pathway, is required for intestinal secretory cell differentiation. Our aim was fourfold: 1) determine whether Hath1 is able to alter the phenotype of colon c
Externí odkaz:
https://doaj.org/article/8deebff4406549f7a0fbb11cc3573ee6
Autor:
Amaury Druet, Caroline Viala, Yann Touchefeu, Jean-François Mosnier, Tamara Matysiak-Budnik, Erwan Corbineau
Publikováno v:
Clinical Colorectal Cancer. 21:e98-e101
Clinical Practice Points • Sinusoidal obstruction syndrome (SOS) is a life-threatening complication of oxaliplatin-based chemotherapy. • Nodular regenerative hyperplasia can be associated at a late stage of SOS, and should be suspected in case of
Autor:
Riad Abes, Kevin Biteau, Alexandre Glémain, Christophe Blanquart, Dominique Costantini, Catherine Ruiz, David Laplaud, Hélène Aublé, Stéphanie Le Bas-Bernardet, E. Sergio Trombetta, Véronique Catros, Gilles Blancho, Isabelle Archambeaud, Sylvie Métairie, Isabelle Girault, Emmanuelle Wilhelm, Masayuki Miyasaka, Jean-François Mosnier, Vanessa Gauttier, Sabrina Pengam, Charlène Trilleaud, Alexandra Garcia, Pierre-Antoine Gouraud, Pierre Duplouye, Bernard Martinet, Géraldine Teppaz, Georgia Porto, Fabienne Haspot, Sarah Bruneau, Aurore Morello, Justine Durand, Caroline Mary, Richard Danger, Sophie Conchon, Nathalie Labarrière, Kerry L. M. Ralph, Virginie Thepenier, Nicolas Vince, Nicolas Poirier, Bernard Vanhove, Virginie Vignard, Mélanie Néel, Safa Dehmani
Publikováno v:
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2020, 130 (11), pp.6109-6123. ⟨10.1172/JCI135528⟩
Journal of Clinical Investigation, 2020, 130 (11), pp.6109-6123. ⟨10.1172/JCI135528⟩
J Clin Invest
Journal of Clinical Investigation, American Society for Clinical Investigation, 2020, 130 (11), pp.6109-6123. ⟨10.1172/JCI135528⟩
Journal of Clinical Investigation, 2020, 130 (11), pp.6109-6123. ⟨10.1172/JCI135528⟩
J Clin Invest
International audience; T cell exclusion causes resistance to cancer immunotherapies via immune checkpoint blockade (ICB). Myeloid cells contribute to resistance by expressing signal regulatory protein-α (SIRPα), an inhibitory membrane receptor tha