Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Jean‐François Lepage"'
Autor:
Madora Mabika, Kristian Agbogba, Samantha Côté, Sarah Lippé, Émilie Riou, Cécile Cieuta, Jean-François Lepage
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-15 (2023)
Abstract Background Mutations in the GATOR1 complex genes, DEPDC5 and NPRL3, play a major role in the development of lesional and non-lesional focal epilepsy through increased mTORC1 signalling. We aimed to assess the effects of mTORC1 hyperactivatio
Externí odkaz:
https://doaj.org/article/d58bfc4718b74897a9a1d20383163883
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Large-scale neurophysiological markers of action competition have been almost exclusively investigated in the context of instructed choices, hence it remains unclear whether these markers also apply to free choices. This study aimed to compa
Externí odkaz:
https://doaj.org/article/b172317d72054b24b475ec1d143748b8
Publikováno v:
Brain Stimulation, Vol 16, Iss 4, Pp 1126-1127 (2023)
Externí odkaz:
https://doaj.org/article/ef712f6ab3564833bc3e2bcb03ef12a4
Autor:
Louis-Philippe Lafleur, Audrey Murray, Manon Desforges, Kevin Pacheco-Barrios, Felipe Fregni, Sara Tremblay, Dave Saint-Amour, Jean-François Lepage, Hugo Théoret
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Application of transcranial alternating current stimulation (tACS) is thought to modulate ongoing brain oscillations in a frequency-dependent manner. However, recent studies report various and sometimes inconsistent results regarding its cap
Externí odkaz:
https://doaj.org/article/47984d810d744989bd90672f8acb1454
Autor:
Angelina Lacroix, Mélodie Proteau-Lemieux, Samantha Côté, Jamie Near, Steve C.N. Hui, Richard A.E. Edden, Sarah Lippé, Artuela Çaku, François Corbin, Jean-François Lepage
Publikováno v:
Neurobiology of Disease, Vol 174, Iss , Pp 105881- (2022)
Fragile-X syndrome (FXS) and Neurofibromatosis of type 1 (NF-1) are two monogenic disorders sharing neurobehavioral symptoms and pathophysiological mechanisms. Namely, preclinical models of both conditions show overactivity of the mTOR signaling path
Externí odkaz:
https://doaj.org/article/dd05ea7cf2774bfebae823359cf4e7d0
Autor:
Camille Champigny, Florence Morin-Parent, Laurence Bellehumeur-Lefebvre, Artuela Çaku, Jean-François Lepage, François Corbin
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2022)
Background: Limited success of previous clinical trials for Fragile X syndrome (FXS) has led researchers to consider combining different drugs to correct the pleiotropic consequences caused by the absence of the Fragile X mental retardation protein (
Externí odkaz:
https://doaj.org/article/0cd73a9b493b43cc9b16929ae7ec6650
Autor:
Armita Abolghasemi, Maria Paulina Carullo, Ester Cisneros Aguilera, Asma Laroui, Rosalie Plantefeve, Daniela Rojas, Serine Benachenhou, María Victoria Ramírez, Mélodie Proteau-Lemieux, Jean-François Lepage, François Corbin, Mélanie Plourde, Mauricio Farez, Patricia Cogram, Artuela Çaku
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10815 (2022)
Fragile X Syndrome (FXS) is the most prevalent monogenic cause of Autism Spectrum Disorders (ASDs). Despite a common genetic etiology, the affected individuals display heterogenous metabolic abnormalities including hypocholesterolemia. Although chang
Externí odkaz:
https://doaj.org/article/bbb934987c244f5abce6f71deafb8cff
Autor:
Catherine Lachambre, Mélodie Proteau-Lemieux, Jean-François Lepage, Eve-Line Bussières, Sarah Lippé
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252043 (2021)
Developmental coordination disorder (DCD) is a neurodevelopmental disorder affecting primarily motor skills, but attentional and executive impairments are common in affected individuals. Moreover, the presence of neurodevelopmental comorbidities is f
Externí odkaz:
https://doaj.org/article/af7e1ba76fe9436c87c3227738328849
Publikováno v:
Frontiers in Psychology, Vol 9 (2018)
There is evidence of a detrimental effect of emotion on reasoning. Recent studies suggest that this relationship is mediated by working memory, a function closely associated with the dorsolateral prefrontal cortex (dlPFC). Relying on transcranial dir
Externí odkaz:
https://doaj.org/article/4c5fea6bd8714f88b1f26e5d95b17eb1
Autor:
Jean-François Lepage, Olivier Morin-Moncet, Vincent Beaulé, Louis de Beaumont, Francois Champoux, Hugo Théoret
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38754 (2012)
Passive observation of motor actions induces cortical activity in the primary motor cortex (M1) of the onlooker, which could potentially contribute to motor learning. While recent studies report modulation of motor performance following action observ
Externí odkaz:
https://doaj.org/article/1c8225fe076f4a8e80f4119dbb26436c