Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Jean‐François Goossens"'
Publikováno v:
MethodsX, Vol 12, Iss , Pp 102771- (2024)
Emerging pollutants derived from human and animal sources, are present in soils and pose significant environmental and health impacts, even at low concentrations. Their detection in soil is analytically complex due to soil interference and the rapid
Externí odkaz:
https://doaj.org/article/8ff96688c4594344a8ad4d5190903dc4
Autor:
Céline Schulz, Quentin Lemaire, Alexandre Berthier, Amandine Descat, Mostafa Kouach, Anne‐Sophie Vercoutter‐Edouart, Ikram El Yazidi‐Belkoura, Stéphan Hardivillé, Jean‐François Goossens, Philippe Lefebvre, Tony Lefebvre
Publikováno v:
Natural Sciences, Vol 3, Iss 2, Pp n/a-n/a (2023)
Abstract O‐GlcNAcylation is a post‐translational modification belonging to the large group of glycosylations. It consists of the modification of cytoplasmic, nuclear, and mitochondrial proteins with a single N‐acetylglucosamine residue by O‐G
Externí odkaz:
https://doaj.org/article/ef8c5d8469834b5285cbfe60fe031f8c
Autor:
Romain Regnault, Frédérique Klupsch, Hassiba El-Bouazzati, Romain Magnez, Raphaël Le Biannic, Natascha Leleu-Chavain, Hania Ahouari, Hervé Vezin, Régis Millet, Jean-François Goossens, Xavier Thuru, Christian Bailly
Publikováno v:
Molecules, Vol 28, Iss 8, p 3491 (2023)
Orally-active anticancer small molecules targeting the PD-1/PD-L1 immune checkpoint are actively searched. Phenyl-pyrazolone derivatives with a high affinity for PD-L1 have been designed and characterized. In addition, the phenyl-pyrazolone unit acts
Externí odkaz:
https://doaj.org/article/e4b8fd713f14437dbeba68169e10a2a0
Autor:
Natascha Leleu-Chavain, Romain Regnault, Hania Ahouari, Raphaël Le Biannic, Mostafa Kouach, Frédérique Klupsch, Romain Magnez, Hervé Vezin, Xavier Thuru, Christian Bailly, Jean-François Goossens, Régis Millet
Publikováno v:
Molecules, Vol 27, Iss 10, p 3316 (2022)
Small molecules targeting the PD-1/PD-L1 checkpoint are actively searched to complement the anticancer arsenal. Different molecular scaffolds have been reported, including phenyl-pyrazolone derivatives which potently inhibit binding of PD-L1 to PD-1.
Externí odkaz:
https://doaj.org/article/2213cf7b7fe44b0d864af0447bcfb049
Autor:
Heloise Henry, Jean-François Goossens, Mostafa Kouach, Damien Lannoy, David Seguy, Thierry Dine, Pascal Odou, Catherine Foulon
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1081 (2022)
Parenteral-nutrition (PN)-induced hyperglycemia increases morbidity and mortality and must be treated with insulin. Unfortunately, the addition of insulin to a ternary PN admixture leads to a rapid decrease in insulin content. Our study’s objective
Externí odkaz:
https://doaj.org/article/082912b00ff142dfb3726089687318d2
Autor:
Julie Fahier, Branko Vukosavljevic, Laure De Kinder, Hugues Florin, Jean-François Goossens, Maike Windbergs, Florence Siepmann, Juergen Siepmann, Susanne Muschert
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1723 (2021)
The aim of this study was to gain deeper insight into the mass transport mechanisms controlling drug release from polymer-coated pellets using non-invasive analytical tools. Pellet starter cores loaded with verapamil HCl (10% loading, 45% lactose, 45
Externí odkaz:
https://doaj.org/article/0a9fdf2949974371a88bf31daa46613f
Autor:
Aurélie Thelliez, Grégory Hénard, Bruno Delorme, Sonia Chatellier, Cécile Danel, Laurent Ducoroy, Annabelle Dupont, Delphine Garrigue, Stéphanie Genay, Jean-François Goossens, Laurence Goossens, Coralie Havet, Jean-Daniel Hecq, Caroline Maeght, Isabelle Mendel, Tomé Najdovski, Pascal Odou, Guillaume Saint-Lorant, Alexandre Ung, Marie Lecoeur, Bertrand Décaudin
Publikováno v:
Biomolecules, Vol 11, Iss 8, p 1081 (2021)
Potentially toxic plasticizers are commonly added to polyvinyl chloride medical devices for transfusion in order to improve their flexibility and workability. As the plasticizers are not chemically bonded to the PVC, they can be released into labile
Externí odkaz:
https://doaj.org/article/0ec4a3bd93204639af369c52852ff81a
Autor:
Kaoutar Benrahou, Hanae Naceiri Mrabti, Saad Fettach, Mohamed Reda Kachmar, Mostafa Kouach, Jean-François Goossens, Latifa Doudach, Shafi Mahmud, Mohammed Merae Alshahrani, Ahmed Abdullah Al Awadh, Abdelhakim Bouyahya, My El Abbes Faouzi
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, 2022, Oxidative Medicine and Cellular Longevity, 2022, pp.4229981. ⟨10.1155/2022/4229981⟩
Oxidative Medicine and Cellular Longevity, 2022, Oxidative Medicine and Cellular Longevity, 2022, pp.4229981. ⟨10.1155/2022/4229981⟩
Erodium guttatum is widely used in folk medicine in many countries to treat various ailments such as urinary inflammation, diabetes, constipation, and eczema. The aim of this study is the determination of mineral and phenolic compounds of E. guttatum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2661dd7b5d70fc9e3322d6433da131b0
https://doi.org/10.1155/2022/4229981
https://doi.org/10.1155/2022/4229981
Autor:
Fanny Lalloyer, Denis A. Mogilenko, Ann Verrijken, Joel T. Haas, Antonin Lamazière, Mostafa Kouach, Amandine Descat, Sandrine Caron, Emmanuelle Vallez, Bruno Derudas, Céline Gheeraert, Eric Baugé, Gaëtan Despres, Eveline Dirinck, Anne Tailleux, David Dombrowicz, Luc Van Gaal, Jerôme Eeckhoute, Philippe Lefebvre, Jean-François Goossens, Sven Francque, Bart Staels
Publikováno v:
Journal of Hepatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22f0765e49345137380ea96eb720d944
https://doi.org/10.1016/j.jhep.2023.05.012
https://doi.org/10.1016/j.jhep.2023.05.012
Autor:
Céline Schulz, Quentin Lemaire, Alexandre Berthier, Amandine Descat, Mostafa Kouach, Anne‐Sophie Vercoutter‐Edouart, Ikram El Yazidi‐Belkoura, Stéphan Hardivillé, Jean‐François Goossens, Philippe Lefebvre, Tony Lefebvre
Publikováno v:
Natural Sciences. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4a182e7d75661568012c589d97c1c07
https://doi.org/10.1002/ntls.202320001
https://doi.org/10.1002/ntls.202320001