Zobrazeno 1 - 10
of 362
pro vyhledávání: '"Jean‐Christophe Leroux"'
Publikováno v:
Advanced Science, Vol 11, Iss 33, Pp n/a-n/a (2024)
Abstract Oral peptide delivery is trending again. Among the possible reasons are the recent approvals of two oral peptide formulations, which represent a huge stride in the field. For the first time, gastrointestinal (GI) permeation enhancers (PEs) a
Externí odkaz:
https://doaj.org/article/6f0834c408a04a2692cfae770ed155fe
Autor:
Diana Evstafeva, Filip Ilievski, Yinyin Bao, Zhi Luo, Boris Abramovic, Sunghyun Kang, Christian Steuer, Elita Montanari, Tommaso Casalini, Dunja Simicic, Dario Sessa, Stefanita-Octavian Mitrea, Katarzyna Pierzchala, Cristina Cudalbu, Chelsie E. Armbruster, Jean-Christophe Leroux
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Hepatic encephalopathy is a neuropsychiatric complication of liver disease which is partly associated with elevated ammonemia. Urea hydrolysis by urease-producing bacteria in the colon is often mentioned as one of the main routes of ammonia
Externí odkaz:
https://doaj.org/article/0763ec364373410299c94f55dd5b745c
Autor:
Nicole Zoratto, David Klein‐Cerrejon, Daniel Gao, Tino Inchiparambil, David Sachs, Zhi Luo, Jean‐Christophe Leroux
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract Conventional venipuncture is invasive and challenging in low and middle‐income countries. Conversely, point‐of‐care devices paired with fingersticks, although less invasive, suffer from high variability and low blood volume collection.
Externí odkaz:
https://doaj.org/article/adc39f99c374477ea7824a4725e1a0b6
Autor:
Kristin Seltmann, Britta Hettich, Seraina Abele, Selina Gurri, Valeria Mantella, Jean‐Christophe Leroux, Sabine Werner
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 4, Pp n/a-n/a (2024)
Abstract Chloride channel accessory 2 (CLCA2) is a transmembrane protein, which promotes adhesion of keratinocytes and their survival in response to hyperosmotic stress. Here we show that CLCA2 is transported to the nucleus of keratinocytes via extra
Externí odkaz:
https://doaj.org/article/156d9ab2bd824364b432d168f412a94e
Autor:
Sarah Schleich, Peter Kronen, Adva Krivitsky, Nevena Paunović, Coulter Fergal Brian, Agnieszka Anna Karol, Anna Geks, Yinyin Bao, Jean-Christophe Leroux, Brigitte von Rechenberg, Daniel Franzen, Karina Klein
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0300847 (2024)
To date, several types of airway stents are available to treat central airway obstructions. However, the ideal stent that can overcome anatomical, mechanical and microbiological issues is still awaited. In addition, therapeutic effect and self-elimin
Externí odkaz:
https://doaj.org/article/6f2001b5cf3648cca4da3851b708a881
Autor:
Safira Noor Anindita, Riccardo Conti, Doris Zauchner, Nevena Paunović, Wanwan Qiu, Marina Green Buzhor, Adva Krivitsky, Zhi Luo, Ralph Müller, Hansjörg Grützmacher, Xiao‐Hua Qin, Jean‐Christophe Leroux, Yinyin Bao
Publikováno v:
Aggregate, Vol 4, Iss 6, Pp n/a-n/a (2023)
Abstract Digital light processing (DLP) of structurally complex poly(ethylene glycol) (PEG) hydrogels with high mechanical toughness represents a long‐standing challenge in the field of 3D printing. Here, we report a 3D printing approach for the hi
Externí odkaz:
https://doaj.org/article/585cf32184dc46c6b1a6d66e1ec02cdd
Autor:
Anastasia Spyrogianni, Charlotte Gourmel, Leopold Hofmann, Jessica Marbach, Jean-Christophe Leroux
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Reliable ammonia quantification assays are essential for monitoring ammonemia in patients with liver diseases. In this study, we describe the development process of a microplate-based assay for accurate, precise, and robust ammonia quantific
Externí odkaz:
https://doaj.org/article/b78edb55964b4e9caae71087417608c5
Autor:
Antonia E. Schantl, Anja Verhulst, Ellen Neven, Geert J. Behets, Patrick C. D’Haese, Marc Maillard, David Mordasini, Olivier Phan, Michel Burnier, Dany Spaggiari, Laurent A. Decosterd, Mark G. MacAskill, Carlos J. Alcaide-Corral, Adriana A. S. Tavares, David E. Newby, Victoria C. Beindl, Roberto Maj, Anne Labarre, Chrismita Hegde, Bastien Castagner, Mattias E. Ivarsson, Jean-Christophe Leroux
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Cardiovascular calcification is a serious pathology for which effective pharmacological treatments are lacking. Here the authors show that an optimized oligo(ethylene glycol) derivative of inositol phosphate interferes with calcium phosphate crystall
Externí odkaz:
https://doaj.org/article/af7eef951f974f1d9573843564c6bad9
Autor:
Martina Vranova, Mona C. Friess, Neda Haghayegh Jahromi, Victor Collado-Diaz, Angela Vallone, Olivia Hagedorn, Maria Jadhav, Ann-Helen Willrodt, Anna Polomska, Jean-Christophe Leroux, Steven T. Proulx, Cornelia Halin
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Abstract The interleukin 7 receptor alpha chain (IL-7Rα) is predominately expressed by lymphocytes, and activation by its ligand IL-7 supports the development and maintenance of T cells and boosts T-cell mediated immunity. We recently reported that
Externí odkaz:
https://doaj.org/article/5f21cf0cfca3477eb75f31012925eeff
Publikováno v:
CHIMIA, Vol 75, Iss 5 (2021)
Externí odkaz:
https://doaj.org/article/efd5904dd2c8463aada3a56ee02f7623