Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jean, Wakim"'
Autor:
Lee, Roth, Jean, Wakim, Elad, Wasserman, Moran, Shalev, Esther, Arman, Merle, Stein, Vlad, Brumfeld, Cari A, Sagum, Mark T, Bedford, Jan, Tuckermann, Ari, Elson
Publikováno v:
Science signaling. 12(563)
Bone resorption by osteoclasts is essential for bone homeostasis. The kinase Src promotes osteoclast activity and is activated in osteoclasts by the receptor-type tyrosine phosphatase PTPROt. In other contexts, however, PTPROt can inhibit Src activit
Autor:
Mark T. Bedford, Ari Elson, Jan Tuckermann, Esther Arman, Moran Shalev, Jean Wakim, Merle Stein, Vlad Brumfeld, Cari A. Sagum, Elad Wasserman, Lee Roth
Publikováno v:
Science Signaling. 12
Bone resorption by osteoclasts is essential for bone homeostasis. The kinase Src promotes osteoclast activity and is activated in osteoclasts by the receptor-type tyrosine phosphatase PTPROt. In other contexts, however, PTPROt can inhibit Src activit
Autor:
Eszter Bakos, Matthias P. Kramer, Idit Shachar, Esther Arman, Shirly Becker-Herman, Ari Elson, Jean Wakim
Publikováno v:
Oncogene. 36(26)
The tyrosine phosphatase PTPROt is a suggested tumor suppressor (TS) in B-cell chronic lymphocytic leukemia (CLL), and its expression is reduced in this disease. In order to examine how reduced PTPROt expression affects CLL in vivo we induced CLL in
Autor:
Jean Wakim, Georg Mahlknecht, Michael Sela, Rotem Sertchook, Yosef Yarden, Esther J. Witsch, Erez M. Bublil
Publikováno v:
International immunology. 23(6)
The erbb-2 gene receptor is often over-expressed in human cancer and its overexpression is accompanied by worse prognosis. Targeting erbb-2 gene with antibodies is an effective approach to curtail the progression of erbb-2 gene-expressing cancer type
Autor:
Tony Ng, Takamune Takahashi, Angela Liu, Gabi Tarcic, Tai Kiuchi, Felicia Reinitz, David Nathanson, Shlomit Boguslavsky, Paul S. Mischel, Yosef Yarden, Jean Wakim
Publikováno v:
Current Biology. (21):1788-1798
Summary Background The epidermal growth factor (EGF) stimulates rapid tyrosine phosphorylation of the EGF receptor (EGFR). This event precedes signaling from both the plasma membrane and from endosomes, and it is essential for recruitment of a ubiqui