Zobrazeno 1 - 10
of 578
pro vyhledávání: '"Jean, Gruenberg"'
Autor:
Lea Assies, José García-Calvo, Francesca Piazzolla, Samantha Sanchez, Takehiro Kato, Luc Reymond, Antoine Goujon, Adai Colom, Javier López-Andarias, Karolína Straková, Dora Mahecic, Vincent Mercier, Margot Riggi, Noemi Jiménez-Rojo, Chloé Roffay, Giuseppe Licari, Maria Tsemperouli, Frederik Neuhaus, Alexandre Fürstenberg, Eric Vauthey, Sascha Hoogendoorn, Marcos Gonzalez-Gaitan, Andreas Zumbuehl, Kaori Sugihara, Jean Gruenberg, Howard Riezman, Robbie Loewith, Suliana Manley, Aurelien Roux, Nicolas Winssinger, Naomi Sakai, Stefan Pitsch, Stefan Matile
Publikováno v:
CHIMIA, Vol 75, Iss 12 (2021)
This article describes four fluorescent membrane tension probes that have been designed, synthesized, evaluated, commercialized and applied to current biology challenges in the context of the NCCR Chemical Biology. Their names are Flipper-TR©, ER Fl
Externí odkaz:
https://doaj.org/article/bc42a5ddeb734d338971c739fd7fea45
Autor:
Fabrizio Vacca, Stefania Vossio, Vincent Mercier, Dimitri Moreau, Shem Johnson, Cameron C. Scott, Jonathan Paz Montoya, Marc Moniatte, Jean Gruenberg
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 4, Pp 832-843 (2019)
In specialized cell types, lysosome-related organelles support regulated secretory pathways, whereas in nonspecialized cells, lysosomes can undergo fusion with the plasma membrane in response to a transient rise in cytosolic calcium. Recent evidence
Externí odkaz:
https://doaj.org/article/03a94e5e3de84b1297cc7cc7ca42650b
Autor:
Marc Lenoir, Cansel Ustunel, Sandya Rajesh, Jaswant Kaur, Dimitri Moreau, Jean Gruenberg, Michael Overduin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Sorting nexin 3 (SNX3) is a phosphatidylinositol 3-phosphate binding protein that localizes to early endosomes. Here the authors use NMR to resolve SNX3′s membrane interactions, revealing that membrane binding is regulated through phosphorylation o
Externí odkaz:
https://doaj.org/article/86b2c9b181b3493589dd4feb5d76f8d4
Publikováno v:
eLife, Vol 7 (2018)
How trafficking pathways and organelle abundance adapt in response to metabolic and physiological changes is still mysterious, although a few transcriptional regulators of organellar biogenesis have been identified in recent years. We previously foun
Externí odkaz:
https://doaj.org/article/e61b47e3ee82483597fbb0a677270115
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Late endosome and lysosomes form the second major membrane network along the endocytic pathway, after early/recycling endosomes, and as such, late endosomes function as the last portal before lysosomes. In mammalian cells, they also link the endosoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7748628fd3ec2c56995d419c09c73d54
https://doi.org/10.1016/b978-0-12-821618-7.00106-1
https://doi.org/10.1016/b978-0-12-821618-7.00106-1
Autor:
Gareth Griffiths, Jean Gruenberg, Mark Marsh, Jens Wohlmann, Arwyn T. Jones, Robert G. Parton
Nanoparticles (NP) are attractive options for the therapeutic delivery of active pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research into the development and application of NP most often starts with a diverse gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75387e1b1a6ff87865ca8f50a5ccf934
Autor:
Dimitri Moreau, Jean Gruenberg
Publikováno v:
CHIMIA, Vol 70, Iss 12 (2016)
Imaged-based screening has been developing extremely quickly in the past 10 years. Academic institutes quickly realized that the discovery capacity of this technology was huge, allowing the automatic detection and quantification of complex cell pheno
Externí odkaz:
https://doaj.org/article/8941930760b243c4a498ea5c5a0a6bd8
Autor:
Berend Snijder, Raphael Sacher, Pauli Rämö, Prisca Liberali, Karin Mench, Nina Wolfrum, Laura Burleigh, Cameron C Scott, Monique H Verheije, Jason Mercer, Stefan Moese, Thomas Heger, Kristina Theusner, Andreas Jurgeit, David Lamparter, Giuseppe Balistreri, Mario Schelhaas, Cornelis A M De Haan, Varpu Marjomäki, Timo Hyypiä, Peter J M Rottier, Beate Sodeik, Mark Marsh, Jean Gruenberg, Ali Amara, Urs Greber, Ari Helenius, Lucas Pelkmans
Publikováno v:
Molecular Systems Biology, Vol 8, Iss 1, Pp 1-18 (2012)
Abstract Isogenic cells in culture show strong variability, which arises from dynamic adaptations to the microenvironment of individual cells. Here we study the influence of the cell population context, which determines a single cell's microenvironme
Externí odkaz:
https://doaj.org/article/099ab570f30a48879d45bf21e977d966
Autor:
Aurélien Roux, Jean Gruenberg, Guillaume Molinard, Vincent Mercier, Antoine Goujon, Stefan Matile, Jorge Larios
Publikováno v:
médecine/sciences
médecine/sciences, EDP Sciences, 2021, 37 (8-9), pp.697-700. ⟨10.1051/medsci/2021096⟩
médecine/sciences, 2021, 37 (8-9), pp.697-700. ⟨10.1051/medsci/2021096⟩
Médecine/Sciences, Vol. 37, No 8-9 (2021) pp. 697-700
médecine/sciences, EDP Sciences, 2021, 37 (8-9), pp.697-700. ⟨10.1051/medsci/2021096⟩
médecine/sciences, 2021, 37 (8-9), pp.697-700. ⟨10.1051/medsci/2021096⟩
Médecine/Sciences, Vol. 37, No 8-9 (2021) pp. 697-700
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::526b9aa8b1fc2f2343c08c9926946582
https://hal.archives-ouvertes.fr/hal-03337372/document
https://hal.archives-ouvertes.fr/hal-03337372/document
Autor:
Jean Gruenberg
Publikováno v:
Traffic (Copenhagen, Denmark)
The late endosomes/endo‐lysosomes of vertebrates contain an atypical phospholipid, lysobisphosphatidic acid (LBPA) (also termed bis[monoacylglycero]phosphate [BMP]), which is not detected elsewhere in the cell. LBPA is abundant in the membrane syst