Inhibitors of DNA Methylation

Autor: Marie, Lopez, Julie, Gilbert, Jean, Contreras, Ludovic, Halby, Paola B, Arimondo

Publikováno v: Advances in experimental medicine and biology. 1389

DNA methylation is involved in numerous biological processes and is deregulated in human diseases. The modulation of the activity of the enzymes and proteins in charge of DNA methylation, for example, DNA methyltransferases (DNMTs), can represent a p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b1fe29464361347a52a5a19df4105f68
https://pubmed.ncbi.nlm.nih.gov/36350520

Identification of Chemical Probes Targeting MBD2

Autor: Diane Erdmann, Jean Contreras, Rémy A. Le Meur, Bruno Vitorge, Vincent Saverat, Ambre Tafit, Corinne Jallet, Véronique Cadet-Daniel, Corentin Bon, Phannarath Phansavath, Virginie Ratovelomanana-Vidal, Albert Jeltsch, Sophie Vichier-Guerre, J. Iñaki Guijarro, Paola B. Arimondo

Publikováno v: ACS Chemical Biology
ACS Chemical Biology, 2022, Published as part of the ACS Chemical Biology special issue “Epigenetics 2022”., 17 (6), pp.1415-1426. ⟨10.1021/acschembio.1c00959⟩

International audience; Epigenetics has received much attention in the past decade. Many insights on epigenetic (dys)regulation in diseases have been obtained, and clinical therapies targeting them are in place. However, the readers of the epigenetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5acb0f8d3441c15e8b36496ba011807
https://hal-pasteur.archives-ouvertes.fr/pasteur-03688129