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Autor:
Lee, Jessica C., Stanley, Menacherry, Diehl, Malissa C., Giffear, Mary D., Jo White, C., Rob, Juba1, Bagarazzi1, Mark L., Karuppiah, Muthumani4, Jean, Boyer4, Vipin, Agarwal5, Nicoletti, F, Stephen, Bart, Joseph Kim, J., Weiner, David B., Sardesai, Niranjan Y.
Publikováno v:
Clinical pharmacology in drug development. 5(2)
VGX-1027, a novel oral immune modulator, is under development for the treatment of rheumatoid arthritis. The safety, tolerability, and pharmacokinetics of single (1-800 mg) and multiple (40-400 mg) oral doses were evaluated in 2 clinical studies. The