Zobrazeno 1 - 10
of 258
pro vyhledávání: '"Je-Yoel Cho"'
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 3, Pp 734-746 (2024)
Abstract Metastases originate from primary tumors and reach distant organs. Growing evidence suggests that metastases are under the control of primary tumors even outside the primary site; however, the mechanisms by which primary tumors remotely cont
Externí odkaz:
https://doaj.org/article/033c8ab72ce2478e9ba4a65115119df1
Autor:
Hui-Su Kim, Je-Yoel Cho
Publikováno v:
Proteome Science, Vol 22, Iss 1, Pp 1-49 (2024)
Abstract Objective Numerous evidence has highlighted the differences between primary tumors and metastases. Nonetheless, the differences in exosomal proteins derived from primary tumor and metastases remain elusive. Here, we aimed to identify differe
Externí odkaz:
https://doaj.org/article/56c4f223b08a46268f8fa39e19528c4e
Autor:
Yong Geun Jeon, Hahn Nahmgoong, Jiyoung Oh, Dabin Lee, Dong Wook Kim, Jane Eunsoo Kim, Ye Young Kim, Yul Ji, Ji Seul Han, Sung Min Kim, Jee Hyung Sohn, Won Taek Lee, Sun Won Kim, Jeu Park, Jin Young Huh, Kyuri Jo, Je-Yoel Cho, Jiyoung Park, Jae Bum Kim
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract In mammals, brown adipose tissue (BAT) and inguinal white adipose tissue (iWAT) execute sequential thermogenesis to maintain body temperature during cold stimuli. BAT rapidly generates heat through brown adipocyte activation, and further iWA
Externí odkaz:
https://doaj.org/article/893240ee8ebd4861b31b0ae25b073103
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27148- (2024)
Breast cancer (BC) remains a significant global health threat, with triple-negative breast cancer (TNBC) standing out as a particularly aggressive subtype lacking targeted therapies. Addressing this gap, we propose Quiescin Q6 sulfhydryl oxidase 2 (Q
Externí odkaz:
https://doaj.org/article/b657016ae0dd4fa0a79d2025ebc12038
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Background Genome-wide dysregulation of CpG methylation accompanies tumor progression and characteristic states of cancer cells, prompting a rationale for biomarker development. Understanding how the archetypic epigenetic modification determ
Externí odkaz:
https://doaj.org/article/29ca0765238a4ae6950396fc04676056
Autor:
Ji Hoon Oh, Je-Yoel Cho
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 4, Pp 725-734 (2023)
Abstract Comparative oncology is a field of study that has been recently adopted for studying cancer and developing cancer therapies. Companion animals such as dogs can be used to evaluate novel biomarkers or anticancer targets before clinical transl
Externí odkaz:
https://doaj.org/article/6e95e3060b4643589e84206d0f791fb6
Autor:
Mark Borris D Aldonza, Junghwa Cha, Insung Yong, Jayoung Ku, Pavel Sinitcyn, Dabin Lee, Ryeong-Eun Cho, Roben D Delos Reyes, Dongwook Kim, Soyeon Kim, Minjeong Kang, Yongsuk Ku, Geonho Park, Hye-Jin Sung, Han Suk Ryu, Sukki Cho, Tae Min Kim, Pilnam Kim, Je-Yoel Cho, Yoosik Kim
Publikováno v:
eLife, Vol 12 (2023)
Cancer secretome is a reservoir for aberrant glycosylation. How therapies alter this post- translational cancer hallmark and the consequences thereof remain elusive. Here, we show that an elevated secretome fucosylation is a pan-cancer signature of b
Externí odkaz:
https://doaj.org/article/04cffef7074f4c568c8aa2b97115d57f
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0286814 (2023)
Retroelements (REs) had been considered 'Junk' until the encyclopedia of DNA elements (ENCODE) project demonstrated that most genome is functional. Although the function of retroelements has been reported in diverse cancers including human breast can
Externí odkaz:
https://doaj.org/article/8d381121bb204ccea2c94a53af3da342
Autor:
Hanjun Lee, Seo Yihl Kim, Dong Wook Kim, Young Soo Park, Jin-Hyeok Hwang, Sukki Cho, Je-Yoel Cho
Publikováno v:
Heliyon, Vol 8, Iss 12, Pp e12359- (2022)
While the link between serum proteins and cancer has been studied in an effort to enable early-stage cancer detection, factors that might perturb this link has been poorly understood. To ask this question, we performed serum protein profiling on a pr
Externí odkaz:
https://doaj.org/article/46801254e65745458aa367de5f19af14
Publikováno v:
Redox Biology, Vol 54, Iss , Pp 102359- (2022)
Chemokines have been well-documented as a major factor in immune cell migration and the regulation of immune responses. However, recent studies have reported that chemokines have diverse roles, both in immune cells and other cell types, including adi
Externí odkaz:
https://doaj.org/article/d6bc71add6bb45109c5a3886df8684a4