Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Je Ken Chang"'
Autor:
Chin-Wen Hsieh, Ling-Hua Chang, Yan-Hsiung Wang, Wei-Ting Li, Je-Ken Chang, Chung-Hwan Chen, Mei-Ling Ho
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8770 (2024)
Uremic toxins cause bone disorders in patients with chronic kidney disease (CKD). These disorders are characterized by low turnover osteodystrophy and impaired bone formation in the early stages of CKD. Evidence indicates that the aryl hydrocarbon re
Externí odkaz:
https://doaj.org/article/4c3a3107309b46729727dd847ae030f6
Publikováno v:
Osteoporosis and Sarcopenia, Vol 9, Iss 4, Pp S14- (2023)
Externí odkaz:
https://doaj.org/article/40dd703d871a4f1888b20d9d4aa042aa
Autor:
Ling-Hua Chang, Shun-Cheng Wu, Chung-Hwan Chen, Jhen-Wei Chen, Wan-Chun Huang, Che-Wei Wu, Yi-Shan Lin, Yu-Ju Chen, Je-Ken Chang, Mei-Ling Ho
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13414 (2023)
Osteoarthritis (OA) is the most common age-related degenerative joint disease. Inflammaging, linking inflammation and aging, is found in senescent cells with the secretions of matrix-degrading proteins and proinflammatory cytokines. The senescence-as
Externí odkaz:
https://doaj.org/article/a2c1933399eb4938a26a3f1f668a23cd
Publikováno v:
Journal of Orthopaedic Translation, Vol 30, Iss , Pp 16-30 (2021)
Background: Cyclooxygenase-2 (COX-2) inhibitors are prescribed for the management of osteoarthritis (OA)-associated pain and inflammation. However, the role of COX-2 in normal and osteoarthritic articular chondrocytes has not been well investigated.
Externí odkaz:
https://doaj.org/article/0a314166e05e484580e580c1888654c6
Autor:
Chung-Hwan Chen, Lin Kang, Ling-Hua Chang, Tsung-Lin Cheng, Sung-Yen Lin, Shun-Cheng Wu, Yi-Shan Lin, Shu-Chun Chuang, Tien-Ching Lee, Je-Ken Chang, Mei-Ling Ho
Publikováno v:
Bone & Joint Research, Vol 10, Iss 8, Pp 514-525 (2021)
Aims: Osteoarthritis (OA) is prevalent among the elderly and incurable. Intra-articular parathyroid hormone (PTH) ameliorated OA in papain-induced and anterior cruciate ligament transection-induced OA models; therefore, we hypothesized that PTH impro
Externí odkaz:
https://doaj.org/article/c948a92f38b244a29eea33a29aec310d
Autor:
Lin Kang, Ai-Lun Yang, Chao-Han Lai, Tsan-Ju Chen, Sung-Yen Lin, Yan-Hsiung Wang, Chau-Zen Wang, Edward M. Conway, Hua-Lin Wu, Mei-Ling Ho, Je-Ken Chang, Chung-Hwan Chen, Tsung-Lin Cheng
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9522 (2023)
Osteoarthritis (OA) is a prevalent form of arthritis that affects over 32.5 million adults worldwide, causing significant cartilage damage and disability. Unfortunately, there are currently no effective treatments for OA, highlighting the need for no
Externí odkaz:
https://doaj.org/article/23ab7a9d6d6c4e1cbafdc172de10092d
Publikováno v:
Healthcare, Vol 11, Iss 3, p 329 (2023)
Arthroplasty for the hip/knee and surgeries for hip fractures are increasing worldwide. The aims of this study were to investigate changes in health-related quality of life (HRQOL) after surgery with an early mobility education program, and to explor
Externí odkaz:
https://doaj.org/article/94cd110bf56b479dbed332f1dc832523
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Estrogen enhances long bone longitudinal growth during early puberty. Growth plate chondrocytes are the main cells that contribute to long bone elongation. The role of G-protein-coupled estrogen receptor-1 (GPER-1) in regulating growth plate chondroc
Externí odkaz:
https://doaj.org/article/18ecaa543096440fb95225e5a96fec58
Autor:
Tien-Ching Lee, Hui-Ting Chen, I-Chun Tai, Li-Ting Kao, Ming-Hsin Hung, Chung-Hwan Chen, Yin-Chih Fu, Yan-Hsiung Wang, Chih-Ming Kao, Je-Ken Chang, Mei-Ling Ho
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1915 (2022)
Large bone defects may develop fracture nonunion, leading to disability and psychosocial burdens. Bone grafting with anabolic agents is a good autografting alternative. Simvastatin, as a cholesterol-lowering agent worldwide, is proven to enhance oste
Externí odkaz:
https://doaj.org/article/7c336e5d69ed430e9ed58e294c3f100d
Autor:
Mei-Ling Ho, Chin-Jung Hsu, Che-Wei Wu, Ling-Hua Chang, Jhen-Wei Chen, Chung-Hwan Chen, Kui-Chou Huang, Je-Ken Chang, Shun-Cheng Wu, Pei-Lin Shao
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1752 (2022)
Adipose-derived stem cells (ADSCs) are a type of mesenchymal stem cell that is investigated in bone tissue engineering (BTE). Osteoblasts are the main cells responsible for bone formation in vivo and directing ADSCs to form osteoblasts through osteog
Externí odkaz:
https://doaj.org/article/8ef240aa6f724da4a8b965bf65bf8ffb