Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Je‐Hyun Yoon"'
Autor:
Kyung-Won Min, Myung Hyun Jo, Minseok Song, Ji Won Lee, Min Ji Shim, Kyungmin Kim, Hyun Bong Park, Shinwon Ha, Hyejin Mun, Ahsan Polash, Markus Hafner, Jung-Hyun Cho, Dongsan Kim, Ji-Hoon Jeong, Seungbeom Ko, Sungchul Hohng, Sung-Ung Kang, Je-Hyun Yoon
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 1-15 (2024)
ABSTRACTAlthough Argonaute (AGO) proteins have been the focus of microRNA (miRNA) studies, we observed AGO-free mature miRNAs directly interacting with RNA-binding proteins, implying the sophisticated nature of fine-tuning gene regulation by miRNAs.
Externí odkaz:
https://doaj.org/article/2031b122a0b248eea1c5236fa50038ff
Autor:
Ruhi Gulati, Michael Johnston, Maria Rivas, Ashley Cast, Meenasri Kumbaji, Margaret A. Hanlon, Sanghoon Lee, Ping Zhou, Charissa Lake, Emily Schepers, Kyung‐Won Min, Je‐Hyun Yoon, Rebekah Karns, Lola M. Reid, Dolores Lopez‐Terrada, Lubov Timchenko, Sreeja Parameswaran, Matthew T. Weirauch, Sarangarajan Ranganathan, Alexander Bondoc, James Geller, Gregory Tiao, Soona Shin, Nikolai Timchenko
Publikováno v:
Hepatology Communications, Vol 6, Iss 10, Pp 2950-2963 (2022)
Abstract Fibrolamellar hepatocellular carcinoma (FLC) is a disease that occurs in children and young adults. The development of FLC is associated with creation of a fusion oncoprotein DNAJB1‐PKAc kinase, which activates multiple cancer‐associated
Externí odkaz:
https://doaj.org/article/3b39dff74afb4b70b221609038dea359
Autor:
Taeyun A. Lee, Heonjong Han, Ahsan Polash, Seok Keun Cho, Ji Won Lee, Eun A. Ra, Eunhye Lee, Areum Park, Sujin Kang, Junhee L. Choi, Ji Hyun Kim, Ji Eun Lee, Kyung-Won Min, Seong Wook Yang, Markus Hafner, Insuk Lee, Je-Hyun Yoon, Sungwook Lee, Boyoun Park
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The nucleolus is the traditional site for ribosomal RNA biogenesis. Here, the authors find that the nucleolus is a site of inflammatory pre-mRNA turnover and elucidated how immune homeostasis can be maintained by controlling inflammatory gene express
Externí odkaz:
https://doaj.org/article/3900adf1879d4f5d8d92fd2ebe8a5501
Autor:
Ji Won Lee, Hyejin Mun, Jeong-Hyun Kim, Seungbeom Ko, Young-Kook Kim, Min Ji Shim, Kyungmin Kim, Chul Woong Ho, Hyun Bong Park, Meesun Kim, Chaeyoung Lee, Si Ho Choi, Jung-Woong Kim, Ji-Hoon Jeong, Je-Hyun Yoon, Kyung-Won Min, Tae Gen Son
Publikováno v:
Biology, Vol 12, Iss 12, p 1533 (2023)
Although ionizing radiation (IR) is widely used for therapeutic and research purposes, studies on low-dose ionizing radiation (LDIR) are limited compared with those on other IR approaches, such as high-dose gamma irradiation and ultraviolet irradiati
Externí odkaz:
https://doaj.org/article/d498601a00054471b02e912aa1032671
Autor:
Senyo S. Whyte, Rebekah Karns, Kyung‐Won Min, Jung‐Hyun Cho, Sanghoon Lee, Charissa Lake, Alexander Bondoc, Je‐Hyun Yoon, Soona Shin
Publikováno v:
Cancer Reports, Vol 6, Iss 1, Pp n/a-n/a (2023)
Abstract Background Pediatric hepatocellular carcinoma (HCC) is a group of liver cancers whose mechanisms behind their pathogenesis and progression are poorly understood. Aim We aimed to identify alterations in the expression of miRNAs and their puta
Externí odkaz:
https://doaj.org/article/6bcf8f176bdb4ce09cc9364855d78339
Autor:
Yeo Jin Shin, Eun‐Soo Kwon, Seung‐Min Lee, Seon‐Kyu Kim, Kyung‐Won Min, Jae‐Young Lim, Bora Lee, Jae Sook Kang, Ju Yeon Kwak, Young Hoon Son, Jeong Yi Choi, Yong Ryul Yang, Seokho Kim, Yeon‐Soo Kim, Hak C. Jang, Yousin Suh, Je‐Hyun Yoon, Kwang‐Pyo Lee, Ki‐Sun Kwon
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 5, Pp 1336-1350 (2020)
Abstract Background The microRNAs (miRNAs) down‐regulated in aged mouse skeletal muscle were mainly clustered within the delta‐like homologue 1 and the type III iodothyronine deiodinase (Dlk1‐Dio3) genomic region. Although clustered miRNAs are
Externí odkaz:
https://doaj.org/article/c8b596c5b6a5455eb5388b7550dc5499
Autor:
Ji Won Lee, Yoo Lim Chun, Ah Young Kim, Lawson T. Lloyd, Seungbeom Ko, Je-Hyun Yoon, Kyung-Won Min
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 782 (2021)
Post-transcriptional gene regulation is an important step in the regulation of eukaryotic gene expression. Subcellular compartmentalization of RNA species plays a crucial role in the control of mRNA turnover, spatial restriction of protein synthesis,
Externí odkaz:
https://doaj.org/article/4c494944f9834921950478e39595a599
Autor:
Cristina M. Ramírez, Chin Sheng Lin, Kotb Abdelmohsen, Leigh Goedeke, Je-Hyun Yoon, Julio Madrigal-Matute, Jose L. Martin-Ventura, Dat T. Vo, Philip J. Uren, Luiz O. Penalva, Myriam Gorospe, Carlos Fernández-Hernando
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 6, Pp 1066-1076 (2014)
ABCA1 is a major regulator of cellular cholesterol efflux and plasma HDL biogenesis. Even though the transcriptional activation of ABCA1 is well established, the posttranscriptional regulation of ABCA1 expression is poorly understood. Here, we invest
Externí odkaz:
https://doaj.org/article/796103e7d8ea4b5eae8516c0e40c2d78
Autor:
Cho-Ah Min, Ji-Sook Yun, Eun Hwa Choi, Ui Wook Hwang, Dong-Hyung Cho, Je-Hyun Yoon, Jeong Ho Chang
Publikováno v:
Crystals, Vol 9, Iss 9, p 472 (2019)
Fatty acid amide hydrolase (FAAH) is a well-characterized member of the amidase signature (AS) family of serine hydrolases. The membrane-bound FAAH protein is responsible for the catabolism of neuromodulatory fatty acid amides, including anandamide a
Externí odkaz:
https://doaj.org/article/1a108fc155054c92b6b8b373f7d2ce7b
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 9, Pp 19202-19229 (2013)
Insulin system including ligands (insulin and IGFs) and their shared receptors (IR and IGFR) are critical regulators of insulin signaling and glucose homeostasis. Altered insulin system is associated with major pathological conditions like diabetes a
Externí odkaz:
https://doaj.org/article/da55a52881dc4add9df121f9a6896153