Výsledky vyhledávání - "Je, Landegent"

Clonal involvement of granulocytes and monocytes, but not of T and B lymphocytes and natural killer cells in patients with myelodysplasia: analysis by X-linked restriction fragment length polymorphisms and polymerase chain reaction of the phosphoglycerate kinase gene

Autor: H van Kamp, WE Fibbe, RP Jansen, M van der Keur, E de Graaff, R Willemze, JE Landegent

Publikováno v: Blood. 80:1774-1780

To determine the clonal nature of hematopoiesis and to assess lineage involvement in patients with myelodysplastic syndromes (MDS), we used restriction fragment length polymorphisms of the X-linked genes phosphoglycerate kinase (PGK1) and hypoxanthin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::abb39537daa270e6d17bff07b1544d55
https://doi.org/10.1182/blood.v80.7.1774.bloodjournal8071774

Zobrazit plný text záznamu

Clonal hematopoiesis in patients with acquired aplastic anemia [see comments]

Autor: H van Kamp, JE Landegent, RP Jansen, R Willemze, WE Fibbe

Publikováno v: Blood. 78:3209-3214

To determine whether patients with acquired asplastic anemia (AA) exhibit clonal hematopoiesis, we used restriction fragment length polymorphisms of the X-linked genes phosphoglycerate kinase (PGK1) and hypoxanthine phosphoribosyltransferase (HPRT) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d95adb32543677524c02521d19a9c8c
https://doi.org/10.1182/blood.v78.12.3209.bloodjournal78123209

Zobrazit plný text záznamu

In vivo production of interleukin-5, granulocyte-macrophage colony- stimulating factor, macrophages colony-stimulating factor, and interleukin-6 during intravenous administration of high-dose interleukin-2 in cancer patients [see comments]

Autor: K Kaushansky, JH Falkenburg, R Willemze, G Wagemaker, N Duinkerken, S Osanto, JE Landegent, J Van Damme, Schaafsma, P Ralph

Publikováno v: Blood. 78:1981-1987

Recombinant human interleukin-2 (IL-2), administered to cancer patients by continuous intravenous (IV) infusion (3 x 10(6) U/m2/d), was found to induce the in vivo production of colony-stimulating factors (CSF). Plasma obtained from patients during I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b125d88638d2f2e6072de250554d5a0
https://doi.org/10.1182/blood.v78.8.1981.1981

Zobrazit plný text záznamu

Persistent clonal excess and skewed T-cell repertoire in T cells from patients with hairy cell leukemia

Autor: Johanna Cornelia Kluin-Nelemans, Mg, Kester, Jj, Melenhorst, Je, Landegent, van de Corput L, Willemze R, Jh, Falkenburg

Publikováno v: Europe PubMed Central

Hairy cell leukemia (HCL) is characterized by a severe T-cell-mediated immune deficiency. At the same time, spontaneous T-cell activation is noted when splenic T cells are studied in vivo and in vitro. Therefore, we searched for oligoclonal T-cell po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::38c793c9724a3d0c2413d25fe0a1fdce
http://europepmc.org/abstract/med/8611705

Zobrazit plný text záznamu

De novo induced mutations in the deoxycytidine kinase (dck) gene in rat leukemic clonal cell lines confer resistance to cytarabine (AraC) and 5-aza-2'-deoxycytidine (DAC)

Autor: Alexander Stegmann, Mw, Honders, Willemze R, Je, Landegent

Publikováno v: Europe PubMed Central

We have investigated whether cytarabine (AraC) or decitabine (DAC) induce deficiency of deoxycytidine kinase (DCK) through different mutations of the dck gene, related to their distinct interference with DNA replication. Also, it is not known whether

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bc6c3ad2ad6dc27c6d814539a9053811
http://europepmc.org/abstract/med/7541096

Zobrazit plný text záznamu

Correction of abnormal T-cell receptor repertoire during interferon-alpha therapy in patients with hairy cell leukemia

Autor: Johanna Cornelia Kluin-Nelemans, Mg, Kester, van deCorput L, Pp, Boor, Je, Landegent, Jj, Dongen, Willemze R, Jh, Falkenburg

Publikováno v: Europe PubMed Central

Patients with the B-cell malignancy hairy cell leukemia (HCL) exhibit a skewed T-cell repertoire with oligoclonal expression or absence of many members of the T-cell receptor (TCR) BV gene families. To evaluate whether interferon-alpha (IFN-alpha) th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ca71e0393ee2f4efc8f144d5d9e58214
http://europepmc.org/abstract/med/9596670

Zobrazit plný text záznamu

Interleukin 4 down-regulates the expression of CD14 and the production of interleukin 6 in acute myeloid leukemia cells

Autor: Jh, Jansen, We, Fibbe, Gj, Wientjens, Van Damme J, Je, Landegent, Willemze R, Johanna Cornelia Kluin-Nelemans

Publikováno v: Europe PubMed Central

On normal monocytes, interleukin 4 (IL-4) down-regulates the production of several proteins that are produced in response to bacterial cell wall lipopolysaccharides (LPS), among others IL-6. In addition, IL-4 was shown to down-regulate the expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::749cc4a62779e922cf0026b52a5ff57c
http://europepmc.org/abstract/med/1725131

Zobrazit plný text záznamu

Hybridocytochemistry as a tool for the investigation of chromatin organization

Autor: van der Ploeg M, van Duijn P, Jg, Bauman, Je, Landegent, Anton Klaas Raap

Publikováno v: Europe PubMed Central

The study of nuclear components in cells and tissues has resulted in a wealth of information with regard to the role of chromatin in cellular processes. Here, a survey is given of procedures which allow the cytochemical investigation of nucleic acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::28e26358e26278eacd986fa3f56bfed5
http://europepmc.org/abstract/med/3904712

Zobrazit plný text záznamu

Transfection of wild-type deoxycytidine kinase (dck) cDNA into an AraC- and DAC-resistant rat leukemic cell line of clonal origin fully restores drug sensitivity

Autor: Alexander Stegmann, Wh, Honders, Willemze R, Vw, Ruiz Haperen, Je, Landegent

Publikováno v: Europe PubMed Central

The AraC-resistant rat leukemic cell line RO/1-A has been shown to have a typical deoxycytidine kinase (DCK)-deficient phenotype and cannot metabolize the antileukemic drugs cytarabine (AraC) and decitabine (DAC). To investigate the relative contribu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::41acb5a2c48c0d6439bc06c11bbd02d1
http://europepmc.org/abstract/med/7532033

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání