Zobrazeno 1 - 10 of 250 pro vyhledávání: '"Je, Klaunig"'
1
Pharmacokinetics and toxicity of the novel oral demethylating agent zebularine in laboratory and tumor bearing dogs
Autor: Cm, Fulkerson, Dhawan D, Dr, Jones, Ve, Marquez, Pa, Jones, Zemin Wang, Wu Q, Je, Klaunig, Lm, Fourez, Pl, Bonney, Dw, Knapp
Publikováno v: Europe PubMed Central
The purpose of this study was to determine the plasma pharmacokinetics (PK) and toxicity of zebularine, an oral cytidine analog with demethylating activity, in dogs. Plasma zebularine concentrations were determined by HPLC-MS/MS following an oral zeb
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ee0e5b6639a5d3bb35a45836ed476a88
https://pubmed.ncbi.nlm.nih.gov/26178438
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2
Role of oxidative stress in the mechanism of dieldrin's hepatotoxicity
Autor: Bachowski S, Kyle Kolaja, Xu Y, Ca, Ketcham, Stevenson DE, Ef, Walborg, Je, Klaunig
Publikováno v: Europe PubMed Central
The production of reactive oxygen species (ROS) by toxic chemicals has been implicated in acute and chronic disease states, including cancer. This increase in cellular ROS can lead to a state of oxidative stress. Many compounds selectively induce hep
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::524f7d5ab209abae746868dbeb58ad99
https://pubmed.ncbi.nlm.nih.gov/9142372
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5
Akademický článek
Mode of action of dieldrin-induced liver tumors: application to human risk assessment.
Autor: Klaunig JE; Department of Environmental and Occupational Health, Indiana University School of Public Health, Bloomington, IN, USA., Cohen SM; Department of Pathology, Microbiology, and Immunology and the Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA.
Publikováno v: Critical reviews in toxicology [Crit Rev Toxicol] 2024 Oct; Vol. 54 (9), pp. 634-658. Date of Electronic Publication: 2024 Jul 30.
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6
Akademický článek
Assessment of the mode of action of perchloroethylene-induced mouse liver tumors.
Autor: Klaunig JE; School of Public Health, Indiana University, Bloomington, IN, USA., Bevan C; Halogenated Solvents Industry Alliance, Inc., Arlington, VA, USA., Gollapudi B; Autumn Ridge Circle N, Midland, MI, USA.
Publikováno v: Toxicology and industrial health [Toxicol Ind Health] 2024 May; Vol. 40 (5), pp. 272-291. Date of Electronic Publication: 2024 Mar 25.
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7
Akademický článek
Evaluating the mode of action of perfluorooctanoic acid-induced liver tumors in male Sprague-Dawley rats using a toxicogenomic approach.
Autor: Li X; Laboratory of Investigative Toxicology and Pathology, Department of Environmental and Occupational Health, Indiana University, Bloomington, IN, USA., Wang Z; Laboratory of Investigative Toxicology and Pathology, Department of Environmental and Occupational Health, Indiana University, Bloomington, IN, USA., Wu Q; Laboratory of Investigative Toxicology and Pathology, Department of Environmental and Occupational Health, Indiana University, Bloomington, IN, USA., Klaunig JE; Laboratory of Investigative Toxicology and Pathology, Department of Environmental and Occupational Health, Indiana University, Bloomington, IN, USA.
Publikováno v: Journal of environmental science and health. Part C, Toxicology and carcinogenesis [J Environ Sci Health C Toxicol Carcinog] 2024; Vol. 42 (3), pp. 189-213. Date of Electronic Publication: 2024 Mar 18.
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8
Akademický článek
Nicotine or marijuana vaping exposure during pregnancy and altered immune responses in offspring.
Autor: Ndeke JM; Department of Epidemiology and Biostatistics, Indiana University School of Public Health, Bloomington, IN 47405, USA., Klaunig JE; Department of Environmental and Occupational Health, Indiana University School of Public Health, Bloomington, IN 47408, USA., Commodore S; Department of Environmental and Occupational Health, Indiana University School of Public Health, Bloomington, IN 47408, USA.
Publikováno v: Journal of environmental exposure assessment [J Environ Expo Assess] 2024; Vol. 3 (1). Date of Electronic Publication: 2024 Apr 15.
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9
Akademický článek
Kinetically-derived maximal dose (KMD) indicates lack of human carcinogenicity of ethylbenzene.
Autor: Burgoon LD; Raptor Pharm & Tox, Ltd, Apex, NC, USA., Borgert CJ; Applied Pharmacology and Toxicology, Inc., University of Florida College of Veterinary Medicine, Gainesville, FL, USA. cjborgert@apt-pharmatox.com., Fuentes C; Oregon State University, Corvallis, OR, USA., Klaunig JE; Indiana University School of Public Health, Bloomington, IN, USA.
Publikováno v: Archives of toxicology [Arch Toxicol] 2024 Jan; Vol. 98 (1), pp. 327-334. Date of Electronic Publication: 2023 Dec 07.
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10
Akademický článek
Quantitative Integration of Mode of Action Information in Dose-Response Modeling and POD Estimation for Nonmutagenic Carcinogens: A Case Study of TCDD.
Autor: Chen Q; Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, Florida, USA., Zhou Y; Department of Environmental and Occupational Health, School of Public Health-Bloomington, Indiana University, Bloomington, Indiana, USA., Ji C; Department of Environmental and Occupational Health, School of Public Health-Bloomington, Indiana University, Bloomington, Indiana, USA., Klaunig JE; Department of Environmental and Occupational Health, School of Public Health-Bloomington, Indiana University, Bloomington, Indiana, USA., Shao K; Department of Environmental and Occupational Health, School of Public Health-Bloomington, Indiana University, Bloomington, Indiana, USA.
Publikováno v: Environmental health perspectives [Environ Health Perspect] 2023 Dec; Vol. 131 (12), pp. 127022. Date of Electronic Publication: 2023 Dec 29.
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