Distinguishing direct binding interactions from allosteric effects in the protease–HK97 prohead I δ domain complex by amide H/D exchange mass spectrometry

Autor: Ganesh S. Anand, Joost Snijder, Rk Huang, Reza Khayat, Ajr Heck, David Veesler, Srinath Krishnamurthy, Je Johnson

Publikováno v: Bacteriophage. 4:e959816

A major question in mapping protein-ligand or protein-protein interactions in solution is to distinguish direct-binding interactions from long-range conformational changes at allosteric sites. We describe here the applicability of amide hydrogen deut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a59bcfb67b317d6c53fb07050955fc9
https://doi.org/10.4161/21597073.2014.959816

Wildfire Effects on Forest Floor and Surface Soil in a Table Mountain Pine-Pitch Pine Forest

Autor: JE Johnson, DA Groeschl, DW Smith

Publikováno v: International Journal of Wildland Fire. 3:149

Wildfire plays a dominant role in creating die environmental and biological conditions necessary for the natural regeneration of mixed Pinus pungens Lamb. (Table Mountain pine)-Pinus rigida Mill. (pitch pine) forests. This study of forest floor and s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d3dd30c41acdadd91f4cca714c08ea3
https://doi.org/10.1071/wf9930149

Fine structural changes in the lateral vestibular nucleus of aging rats

Autor: Jaime Miquel, Jr Je Johnson

Publikováno v: Mechanisms of Ageing and Development. 3:203-224

The fine structure of the lateral vestibular nucleus was investigated in Sprague-Dawley rats, that were sacrified at 4 weeks, 6-8 weeks, 6-8 months, and 18-20 months of age. In the neuronal perikaria, the following age-associated changes were seen wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a096a7a0eac8f10c91205edfc3c8ed
https://doi.org/10.1016/0047-6374(74)90017-7

Metal-free southern bean mosaic virus crystals

Autor: ivan rayment, Je, Johnson, Mg, Rossmann

Publikováno v: Europe PubMed Central

Native southern bean mosaic virus contains a significant number of Mg2+ and Ca2+ ions. These can be removed by treatment with EDTA causing the virus to swell by 7% in radius at alkaline pH values. The swollen virions are susceptible to protease and n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1fe6eda65dcd46c3a5ad1789c3bf08f5
https://pubmed.ncbi.nlm.nih.gov/36382

ASCL1 Restrains ERK1/2 to Promote Survival of a Subset of Neuroendocrine Lung Cancers.

Autor: Martin-Vega A; Department of Pharmacology, UT Southwestern Medical Center, Dallas, Texas., Earnest SA; Department of Pharmacology, UT Southwestern Medical Center, Dallas, Texas., Augustyn A; Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, Dallas, Texas., Wichaidit C; Department of Pharmacology, UT Southwestern Medical Center, Dallas, Texas., Girard L; Department of Pharmacology, UT Southwestern Medical Center, Dallas, Texas.; Department of Pathology, UT Southwestern Medical Center, Dallas, Texas.; Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, Dallas, Texas.; Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas., Peyton M; Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, Dallas, Texas., Minna JD; Department of Pharmacology, UT Southwestern Medical Center, Dallas, Texas.; Department of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas.; Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, Dallas, Texas.; Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas., Johnson JE; Department of Pharmacology, UT Southwestern Medical Center, Dallas, Texas.; Department of Neuroscience, UT Southwestern Medical Center, Dallas, Texas.; Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas., Cobb MH; Department of Pharmacology, UT Southwestern Medical Center, Dallas, Texas.; Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas.

Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2024 Dec 03; Vol. 23 (12), pp. 1789-1800.