Zobrazeno 1 - 10 of 356 pro vyhledávání: '"Jd, Rohrer"'
2
Akademický článek
Primary Progressive Aphasia in Italian and English: A Cross-Linguistic Cohort Study.
Autor: Mazzeo S; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Hardy CJD; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Jiang J; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Morinelli C; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Moschini V; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Brooks E; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Johnson JCS; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Chokesuwattanaskul A; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Giacomucci G; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Volkmer A; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Rohrer JD; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Ingannato A; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Bagnoli S; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Padiglioni S; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Nacmias B; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Sorbi S; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Bessi V; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy., Warren JD; From the Dementia Research Centre (S.M., C.J.D.H., J.J., E.B., J.C.S.J., A.C., J.D.R., J.D.W.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, United Kingdom; Research and Innovation Centre for Dementia-CRIDEM (S.M., C.M., V.M., S.P., S.S., V.B.), Azienda Ospedaliero-Universitaria Careggi, Florence; Vita-Salute San Raffaele University (S.M.), Milan; IRCCS Policlinico San Donato (S.M.), San Donato Milanese, Italy; Division of Neurology (A.C.), Department of Internal Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society; Cognitive Clinical and Computational Neuroscience Research Unit (A.C.), Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; University of Florence (G.G.), Italy; Department of Psychology & Language Sciences (A.V.), University College London, United Kingdom; Department of Neuroscience, Psychology, Drug Research and Child Health (A.I., S.B., B.N., S.S.), University of Florence, Azienda Ospedaliera-Universitaria Careggi; and IRCCS Fondazione Don Carlo Gnocchi (B.N., S.S., V.B.), Florence, Italy.
Publikováno v: Neurology [Neurology] 2024 Dec 24; Vol. 103 (12), pp. e210058. Date of Electronic Publication: 2024 Nov 21.
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3
Akademický článek
Association of Initial Side of Brain Atrophy With Clinical Features and Disease Progression in Patients With GRN Frontotemporal Dementia.
Autor: Borrego-Ecija S; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Juncà-Parella J; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Vandebergh M; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Pérez Millan A; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Balasa M; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Llado A; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Bouzigues A; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Russell LL; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Foster PH; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Ferry-Bolder E; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Van Swieten JC; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Jiskoot LC; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Seelaar H; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Laforce R Jr; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Graff C; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Galimberti D; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Vandenberghe R; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., de Mendonça A; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Tiraboschi P; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Santana I; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Gerhard A; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Levin J; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Sorbi S; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Otto M; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Pasquier F; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Ducharme S; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Butler C; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Le Ber I; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Finger E; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Tartaglia MC; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Masellis M; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Rowe JB; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Synofzik M; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Moreno F; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Borroni B; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Rademakers R; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Rohrer JD; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL., Sánchez-Valle R; From the Alzheimer's Disease and Other Cognitive Disorders Unit (S.B.-E., J.J.-P., A.P.M., M.B., A.L., R.S.-V.), Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Spain; VIB Center for Molecular Neurology (M.V., R.R.); Department of Biomedical Sciences (M.V., R.R.), University of Antwerp, Belgium; Dementia Research Centre (A.B., L.L.R., P.H.F., E.F.-B., J.D.R.), Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom; Department of Neurology (J.C.V.S., L.C.J., H.S.), Erasmus Medical Centre, Rotterdam, Netherlands; Clinique Interdisciplinaire de Mémoire (R.L.), Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Canada; Division of Neurogeriatrics, Bioclinicum (C.G.), Department of Neurobiology, Care Sciences and Society; Center for Alzheimer Research, Karolinska Institutet; Unit for Hereditary Dementias (C.G.), Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden; Department of Biomedical (D.G.), Surgical and Dental Sciences, University of Milan; Fondazione Ca' Granda (D.G.), IRCCS Ospedale Policlinico, Milan, Italy; Laboratory for Cognitive Neurology (R.V.), Department of Neurosciences, KU Leuven; Neurology Service (R.V.), University Hospitals Leuven; Leuven Brain Institute (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Fondazione IRCCS Istituto Neurologico Carlo Besta (P.T.), Milano, Italy; Neurology Service (I.S.), Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra; Center for Neuroscience and Cell Biology (I.S.), Faculty of Medicine, University of Coimbra, Portugal; Division of Psychology Communication and Human Neuroscience (A.G.), Wolfson Molecular Imaging Centre, University of Manchester, United Kingdom; Department of Nuclear Medicine (A.G.), Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen; Department of Geriatric Medicine (A.G.), Klinikum Hochsauerland, Arnsberg; Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) (J.L.); Munich Cluster of Systems Neurology (SyNergy) (J.L.), Munich, Germany; Department of Neurofarba (S.S.), University of Florence; IRCCS Fondazione Don Carlo Gnocchi (S.S.), Florence, Italy; Department of Neurology (M.O.), University of Ulm, Germany; Univ Lille (F.P.), France; Department of Psychiatry (S.D.), McGill University Health Centre, McConnell Brain Imaging Centre (S.D.), Montreal Neurological Institute, McGill University, Montreal, Québec, Canada; Medical Sciences Division (C.B.), Nuffield Department of Clinical Neurosciences, University of Oxford, Department of Brain Sciences (C.B.), Imperial College London, United Kingdom; Sorbonne Université (I.L.B.), Paris Brain Institute-Institut du Cerveau-ICM, Inserm U1127, CNRS UMR 7225; Centre de référence des démences rares ou précoces (I.L.B.), IM2A, Département de Neurologie; Département de Neurologie (I.L.B.), AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London; Tanz Centre for Research in Neurodegenerative Diseases (M.C.T.), Ontario; Sunnybrook Health Sciences Centre (M.M.), Sunnybrook Research Institute, University of Toronto, Canada; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust (J.B.R.), University of Cambridge, United Kingdom; Department of Neurodegenerative Diseases (M.S.), Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Germany; Cognitive Disorders Unit (F.M.), Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Neurology Unit (B.B.), Department of Clinical and Experimental Sciences, University of Brescia, Italy; and Department of Neuroscience (R.R.), Mayo Clinic, Jacksonville, FL.
Publikováno v: Neurology [Neurology] 2024 Dec 10; Vol. 103 (11), pp. e209944. Date of Electronic Publication: 2024 Nov 11.
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Akademický článek
Association of Changes in Cerebral and Hypothalamic Structure With Sleep Dysfunction in Patients With Genetic Frontotemporal Dementia.
Autor: Best PT; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Van Swieten JC; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Jiskoot LC; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Moreno F; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Sánchez-Valle R; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Laforce R Jr; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Graff C; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Masellis M; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Tartaglia C; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Rowe JB; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Borroni B; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Finger E; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Synofzik M; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Galimberti D; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Vandenberghe R; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., de Mendonça A; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Butler C; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Gerhard A; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Le Ber I; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Tiraboschi P; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Santana I; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Pasquier F; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Levin J; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Otto M; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Sorbi S; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Seelaar H; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Bouzigues A; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Cash DM; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Russell LL; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Bocchetta M; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Rohrer JD; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Devenyi GA; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Chakravarty M; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada., Ducharme S; From the Integrated Program in Neuroscience (P.T.B.), McGill, Montréal, Canada; Department of Neurology (J.C.V.S., H.S., L.C.J.), Erasmus Medical Centre, Rotterdam, Netherlands; Department of Neurology (F.M.), Donostia Universitary Hospital, San Sebastián, Spain; Institut D'Investigacións Biomèdiques August Pi I Sunyer (R.S.-V.), University of Barcelona, Spain; Faculté de Médecine (R.L.), Université Laval, Québec City, Canada; Department of Neurobiology (C.G.), Karolinska Institutet, Solna, Sweden; Sunnybrook Research Institute (M.M.), Toronto, Canada; Tanz Centre for Research in Neurodegenerative Diseases (C.T.), University of Toronto, Canada; Department of Clinical Neurosciences (J.B.R.), University of Cambridge, United Kingdom; Department of Clinical and Experimental Sciences (B.B.), University of Brescia, Italy; Department of Clinical Neurological Sciences (E.F.), University of Western Ontario, London, Canada; Hertie-Institute for Clinical Brain Research and Center of Neurology (M.S.), University of Tübingen, Germany; Neurology (D.G.), University of Milan, Italy; Department of Neurosciences (R.V.), KU Leuven, Belgium; Faculty of Medicine (A.M.), University of Lisbon, Portugal; Nuffield Department of Clinical Neurosciences (C.B.), University of Oxford, United Kingdom; Wolfson Molecular Imaging Centre (A.G.), University of Manchester, United Kingdom; Institut du Cerveau-ICM (I.L.B.), Hôpital Pitié-Salpêtrière, Paris, France; 31Fondazione IRCCS (P.T.), Istituto Neurologico Carlo Besta, Milan, Italy; Faculty of Medicine (I.S.), University of Coimbra, Portugal; Department of Neurology (F.P.), Université Lille, France; Department of Neurology (J.L.), Ludwig-Maximilians Universität München, Munich, Germany; Department of Neurology (M.O.), University of Ulm, Germany; Department of Neurofarba (S.S.), University of Florence, Italy; Department of Neurodegenerative Disease (A.B., D.M.C., L.L.R., M.B., J.D.R.), University College London, United Kingdom; and Department of Psychiatry (G.A.D., M.C., S.D.), McGill University, Montréal, Canada.
Publikováno v: Neurology [Neurology] 2024 Dec 10; Vol. 103 (11), pp. e209829. Date of Electronic Publication: 2024 Nov 11.
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5
Akademický článek
A systematic review of the quantitative markers of speech and language of the frontotemporal degeneration spectrum and their potential for cross-linguistic implementation.
Autor: Coppieters R; Computational Neurology, Experimental Neurobiology Unit (ENU), Department of Biomedical Sciences, University of Antwerp, Belgium; VIB Center for Molecular Neurology, VIB, Antwerp, Belgium., Bouzigues A; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK; Paris Brain Institute, Sorbonne University, Paris, France., Jiskoot L; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK; Department of Neurology, Erasmus Medical Centre, Rotterdam, the Netherlands., Montembeault M; Memory and Aging Center, Department of Neurology, University of California, San Francisco USA., Tee BL; Memory and Aging Center, Department of Neurology, University of California, San Francisco USA; Global Brain Health Institute, University of California, San Francisco, USA., Rohrer JD; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK., Bruffaerts R; Computational Neurology, Experimental Neurobiology Unit (ENU), Department of Biomedical Sciences, University of Antwerp, Belgium; Department of Neurology, Antwerp University Hospital, Belgium; Biomedical Research Institute, Hasselt University, Belgium. Electronic address: rose.bruffaerts@uantwerpen.be.
Publikováno v: Neuroscience and biobehavioral reviews [Neurosci Biobehav Rev] 2024 Dec; Vol. 167, pp. 105909. Date of Electronic Publication: 2024 Oct 10.
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6
Akademický článek
Disruption of macroscale functional network organisation in patients with frontotemporal dementia.
Autor: Bouzigues A; Paris Brain Institute - Institut du Cerveau (ICM), Sorbonne Université, Inserm U1127, CNRS UMR 7225, AP-HP - Hôpital Pitié-Salpêtrière, Paris, France. arabella.bouzigues@icm-institute.org.; Dementia Research Centre, Queen Square Institute of Neurology, University College London, London, United Kingdom. arabella.bouzigues@icm-institute.org., Godefroy V; Centre de Recherche en Neurosciences de Lyon (CRNL), Université Claude Bernard Lyon 1, Inserm U1028, CNRS UMR 5292, F-69500, Bron, France., Le Du V; Paris Brain Institute - Institut du Cerveau (ICM), Sorbonne Université, Inserm U1127, CNRS UMR 7225, AP-HP - Hôpital Pitié-Salpêtrière, Paris, France., Russell LL; Dementia Research Centre, Queen Square Institute of Neurology, University College London, London, United Kingdom., Houot M; Paris Brain Institute - Institut du Cerveau (ICM), Sorbonne Université, Inserm U1127, CNRS UMR 7225, AP-HP - Hôpital Pitié-Salpêtrière, Paris, France.; Department of Neurology, Institute of Memory and Alzheimer's Disease, Centre of Excellence of Neurodegenerative Disease, Hôpital Pitié-Salpêtrière, Paris, France., Le Ber I; Paris Brain Institute - Institut du Cerveau (ICM), Sorbonne Université, Inserm U1127, CNRS UMR 7225, AP-HP - Hôpital Pitié-Salpêtrière, Paris, France.; Department of Neurology, Institute of Memory and Alzheimer's Disease, Centre of Excellence of Neurodegenerative Disease, Hôpital Pitié-Salpêtrière, Paris, France., Batrancourt B; Paris Brain Institute - Institut du Cerveau (ICM), Sorbonne Université, Inserm U1127, CNRS UMR 7225, AP-HP - Hôpital Pitié-Salpêtrière, Paris, France., Levy R; Paris Brain Institute - Institut du Cerveau (ICM), Sorbonne Université, Inserm U1127, CNRS UMR 7225, AP-HP - Hôpital Pitié-Salpêtrière, Paris, France.; Department of Neurology, Institute of Memory and Alzheimer's Disease, Centre of Excellence of Neurodegenerative Disease, Hôpital Pitié-Salpêtrière, Paris, France., Warren JD; Dementia Research Centre, Queen Square Institute of Neurology, University College London, London, United Kingdom., Rohrer JD; Dementia Research Centre, Queen Square Institute of Neurology, University College London, London, United Kingdom., Margulies DS; Integrative Neuroscience and Cognition Center, Université de Paris Cité, CNRS, Paris, France.; Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom., Migliaccio R; Paris Brain Institute - Institut du Cerveau (ICM), Sorbonne Université, Inserm U1127, CNRS UMR 7225, AP-HP - Hôpital Pitié-Salpêtrière, Paris, France. lara.migliaccio@gmail.com.; Department of Neurology, Institute of Memory and Alzheimer's Disease, Centre of Excellence of Neurodegenerative Disease, Hôpital Pitié-Salpêtrière, Paris, France. lara.migliaccio@gmail.com.
Publikováno v: Molecular psychiatry [Mol Psychiatry] 2024 Nov 24. Date of Electronic Publication: 2024 Nov 24.
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7
Akademický článek
Elevated Cerebrospinal Fluid Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 in Asymptomatic C9orf72 Hexanucleotide Repeat Expansion Carriers.
Autor: Dellar ER; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Vendrell I; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK., Amein B; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Lester DG; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Edmond EC; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Yoganathan K; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Dharmadasa T; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia., Sogorb-Esteve A; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.; UK Dementia Research Institute at University College London, London, UK., Fischer R; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Chinese Academy of Medical Science Oxford Institute, University of Oxford, Oxford, UK., Talbot K; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, UK., Rohrer JD; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK., Turner MR; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Thompson AG; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Publikováno v: Annals of neurology [Ann Neurol] 2024 Nov 16. Date of Electronic Publication: 2024 Nov 16.
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8
Akademický článek
Barriers and Facilitators to Participation in Clinical Trials Related to Familial Frontotemporal Dementia: A Qualitative Study.
Autor: Zammitt D; ADAPT Lab, Department of Clinical Educational and Health Psychology, University College London, London, UK., Brotherhood EV; Dementia Research Centre, University College London, London, UK., Fearn C; ADAPT Lab, Department of Clinical Educational and Health Psychology, University College London, London, UK., Greaves C; Dementia Research Centre, University College London, London, UK., Hayes O; Dementia Research Centre, University College London, London, UK., Harding E; Dementia Research Centre, University College London, London, UK., Lykourgos M; Department of Clinical Educational and Health Psychology, University College London, London, UK., Rohrer JD; Dementia Research Centre, University College London, London, UK., Stott J; ADAPT Lab, Department of Clinical Educational and Health Psychology, University College London, London, UK.
Publikováno v: Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2024 Nov; Vol. 12 (11), pp. e70038.
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9
Akademický článek
A framework for translating tauopathy therapeutics: Drug discovery to clinical trials.
Autor: Feldman HH; Department of Neurosciences, University of California San Diego, La Jolla, California, USA., Cummings JL; Chambers-Grundy Center for Transformative Neuroscience, Department of Brain Health, School of Integrated Health Sciences, University of Nevada at Las Vegas, Las Vegas, Nevada, USA., Boxer AL; Department of Neurology, Memory and Aging Center, University of California San Francisco, San Francisco, California, USA., Staffaroni AM; Department of Neurology, Memory and Aging Center, University of California San Francisco, San Francisco, California, USA., Knopman DS; Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA., Sukoff Rizzo SJ; Aging Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Territo PR; Department of Medicine, Division of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis, Indiana, USA., Arnold SE; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, Massachusetts, USA., Ballard C; College of Medicine and Health, University of Exeter, Exeter, UK., Beher D; Asceneuron, Lausanne, Switzerland., Boeve BF; Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA., Dacks PA; The Association for Frontotemporal Degeneration, King of Prussia, Pennsylvania, USA., Diaz K; CurePSP, New York, New York, USA., Ewen C; UCB Pharma, Slough, UK., Fiske B; The Michael J. Fox Foundation for Parkinson's Research, New York, New York, USA., Gonzalez MI; Drug Discovery and Development Consultants, Cambridge, UK., Harris GA; Rainwater Charitable Foundation, Fort Worth, Texas, USA., Hoffman BJ; Origami Therapeutics, San Diego, California, USA., Martinez TN; Critical Path Institute, Tucson, Arizona, USA., McDade E; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA., Nisenbaum LK; Alzheimer's Drug Discovery Foundation, New York, New York, USA., Palma JA; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.; Department of Neurology, New York University Grossman School of Medicine, New York, New York, USA., Quintana M; Berry Consultants, Austin, Texas, USA., Rabinovici GD; Department of Neurology, Memory and Aging Center, University of California San Francisco, San Francisco, California, USA., Rohrer JD; Department of Neurodegenerative Disease, Dementia Research Centre, Queen Square Institute of Neurology, University College of London, London, UK., Rosen HJ; Department of Neurology, Memory and Aging Center, University of California San Francisco, San Francisco, California, USA., Troyer MD; Denali Therapeutics, South San Francisco, California, USA., Kim DY; Department of Neurology, Genetics and Aging Research Unit, McCance Center for Brain Health, Mass General Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA., Tanzi RE; Department of Neurology, Genetics and Aging Research Unit, McCance Center for Brain Health, Mass General Institute for Neurodegenerative Disease, Massachusetts General Hospital, Charlestown, Massachusetts, USA., Zetterberg H; Department of Psychiatry and Neurochemistry, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden., Ziogas NK; Biogen, Cambridge, Massachusetts, USA., May PC; ADvantage Neuroscience Consulting LLC, Fort Wayne, Indiana, USA., Rommel A; Rainwater Charitable Foundation, Fort Worth, Texas, USA.
Publikováno v: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Nov; Vol. 20 (11), pp. 8129-8152. Date of Electronic Publication: 2024 Sep 24.
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10
Akademický článek
Inflammatory plasma profile in genetic symptomatic and presymptomatic Frontotemporal Dementia - A GENFI study.
Autor: Fenoglio C; Dept. of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy; Fondazione Ca' Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy., Serpente M; Fondazione Ca' Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy., Arcaro M; Fondazione Ca' Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy., Carandini T; Fondazione Ca' Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy., Sacchi L; Dept. of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy; Fondazione Ca' Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy., Pintus M; Dept. of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy; Fondazione Ca' Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy., Rotondo E; Fondazione Ca' Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy., Borracci V; Fondazione Ca' Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy., Ghezzi L; Dept. of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy; Fondazione Ca' Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy., Bouzigues A; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK., Russell LL; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK., Foster PH; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK., Ferry-Bolder E; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK., van Swieten JC; Department of Neurology, Erasmus Medical Centre, Rotterdam, Netherlands., Jiskoot LC; Department of Neurology, Erasmus Medical Centre, Rotterdam, Netherlands., Seelaar H; Department of Neurology, Erasmus Medical Centre, Rotterdam, Netherlands., Sánchez Valle R; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Fundació Clínic per a la Recerca Biomèdica, Universitat de Barcelona, Barcelona, Spain., Laforce R; Clinique Interdisciplinaire de Mémoire, Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, QC, Canada., Graff C; Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Bioclinicum, Karolinska Institutet, Solna, Sweden; Unit for Hereditary Dementias, Theme Inflammation and Aging, Karolinska University Hospital, Solna, Sweden., Vandenberghe R; Laboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Leuven, Belgium; Neurology Service, University Hospitals Leuven, Leuven, Belgium; Leuven Brain Institute, KU Leuven, Leuven, Belgium., de Mendonça A; Faculty of Medicine, University of Lisbon, Lisbon, Portugal., Tiraboschi P; Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy., Santana I; University Hospital of Coimbra (HUC), Neurology Service, Faculty of Medicine, University of Coimbra, Coimbra, Portugal; Center for Neuroscience and Cell Biology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal., Gerhard A; Division of Psychology Communication and Human Neuroscience, Wolfson Molecular Imaging Centre, University of Manchester, Manchester, UK; Department of Nuclear Medicine, Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen, Essen, Germany; Department of Geriatric Medicine, Klinikum Hochsauerland, Arnsberg, Germany., Levin J; Department of Neurology, Ludwig-Maximilians Universität München, Munich, Germany; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany., Sorbi S; Department of Neurofarba, University of Florence, Italy; IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy., Otto M; Department of Neurology, University of Ulm, Germany., Pasquier F; University of Lille, France; Inserm 1172, Lille, France; CHU, CNR-MAJ, Labex Distalz, LiCEND Lille, France., Ducharme S; Department of Psychiatry, Douglas Mental Health University Institute, McGill University, Montreal, Québec, Canada; McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Québec, Canada., Butler CR; Nuffield Department of Clinical Neurosciences, Medical Sciences Division, University of Oxford, Oxford, UK; Department of Brain Sciences, Imperial College London, UK., Ber IL; Sorbonne Université, Paris Brain Institute - Institut du Cerveau - ICM, Inserm U1127, CNRS UMR 7225, AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Centre de référence des démences rares ou précoces, IM2A, Département de Neurologie, AP-HP - Hôpital Pitié-Salpêtrière, Paris, France; Département de Neurologie, AP-HP - Hôpital Pitié-Salpêtrière, Paris, France., Finger E; Department of Clinical Neurological Sciences, University of Western Ontario, London, ON, Canada., Carmela Tartaglia M; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada., Masellis M; Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, University of Toronto, Toronto, Canada., Rowe JB; Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, UK., Synofzik M; Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany; Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany., Moreno F; Cognitive Disorders Unit, Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain; Biogipuzkoa Health Research Institute, Neurosciences Area, Group of Neurodegenerative Diseases, 20014 San Sebastian, Spain; Center for Biomedical Research in Neurodegenerative Disease (CIBERNED), Carlos III Health Institute, Madrid, Spain., Borroni B; Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Rohrer JD; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK., Arighi A; Fondazione Ca' Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy., Galimberti D; Dept. of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy; Fondazione Ca' Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy. Electronic address: daniela.galimberti@unimi.it.
Publikováno v: Brain, behavior, and immunity [Brain Behav Immun] 2024 Nov; Vol. 122, pp. 231-240. Date of Electronic Publication: 2024 Aug 15.
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