Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Jc, Whittaker"'
Autor:
Ks, Vimaleswaran, Cavadino A, Dj, Berry, LifeLines Cohort Study investigators, Jorde R, Ak, Dieffenbach, Lu C, Ac, Alves, Hj, Heerspink, Tikkanen E, Eriksson J, Wong A, Mangino M, Ka, Jablonski, Im, Nolte, Dk, Houston, Ts, Ahluwalia, Pj, Most, Pasko D, Zgaga L, Thiering E, Vitart V, Rm, Fraser, Je, Huffman, Ra, Boer, Schöttker B, Ku, Saum, Mi, Mccarthy, Dupuis J, Kh, Herzig, Sebert S, Pouta A, Laitinen J, Me, Kleber, Navis G, Lorentzon M, Jameson K, Arden N, Ja, Cooper, Acharya J, Hardy R, Raitakari O, Ripatti S, Lk, Billings, Lahti J, Osmond C, Bw, Penninx, Rejnmark L, Kk, Lohman, Paternoster L, Rp, Stolk, Dg, Hernandez, Byberg L, Hagström E, Melhus H, Ingelsson E, Mellström D, Ljunggren O, Tzoulaki I, McLachlan S, Theodoratou E, Cm, Tiesler, Jula A, Navarro P, Af, Wright, Polasek O, International Consortium for Blood Pressure (ICBP), Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium, Global Blood Pressure Genetics (Global BPGen) consortium, Caroline Hayward, Jf, Wilson, Rudan I, Salomaa V, Heinrich J, Campbell H, Jf, Price, Karlsson M, Lind L, Michaëlsson K, Bandinelli S, Tm, Frayling, Ca, Hartman, Ti, Sørensen, Sb, Kritchevsky, Bl, Langdahl, Jg, Eriksson, Jc, Florez, Td, Spector, Lehtimäki T, Kuh D, Se, Humphries, Cooper C, Ohlsson C, März W, Mh, Borst, Kumari M, Mika Kivimaki, Tj, Wang, Power C, Brenner H, Grimnes G, van der Harst P, Snieder H, Ad, Hingorani, Pilz S, Jc, Whittaker, Järvelin MR, Hyppönen E
Publikováno v:
Europe PubMed Central
BACKGROUND: Low plasma 25-hydroxyvitamin D (25[OH]D) concentration is associated with high arterial blood pressure and hypertension risk, but whether this association is causal is unknown. We used a mendelian randomisation approach to test whether 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::425db1caf29762d177e8497e030e1999
https://researchonline.lshtm.ac.uk/id/eprint/1878076/1/NIHMS721970-supplement-Supplementary_Appendix.pdf
https://researchonline.lshtm.ac.uk/id/eprint/1878076/1/NIHMS721970-supplement-Supplementary_Appendix.pdf
Autor:
Shrine N; Department of Health Sciences, University of Leicester, Leicester, UK., Guyatt AL; Department of Health Sciences, University of Leicester, Leicester, UK., Erzurumluoglu AM; Department of Health Sciences, University of Leicester, Leicester, UK., Jackson VE; Department of Health Sciences, University of Leicester, Leicester, UK.; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Hobbs BD; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Melbourne CA; Department of Health Sciences, University of Leicester, Leicester, UK., Batini C; Department of Health Sciences, University of Leicester, Leicester, UK., Fawcett KA; Department of Health Sciences, University of Leicester, Leicester, UK., Song K; Target Sciences, GlaxoSmithKline, Collegeville, PA, USA., Sakornsakolpat P; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Li X; Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, AZ, USA., Boxall R; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK., Reeve NF; Department of Health Sciences, University of Leicester, Leicester, UK., Obeidat M; The University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada., Zhao JH; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Wielscher M; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, UK., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Kentistou KA; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Cook JP; Department of Biostatistics, University of Liverpool, Liverpool, UK., Sun BB; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Zhou J; Flatiron Institute, Simons Foundation, New York, NY, USA., Hui J; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; School of Population Health, The University of Western Australia, Crawley, Western Australia, Australia.; PathWest Laboratory Medicine of WA, Sir Charles Gairdner Hospital, Crawley, Western Australia, Australia.; School of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia., Karrasch S; Institute of Epidemiology, Helmholtz Zentrum Muenchen-German Research Center for Environmental Health, Neuherberg, Germany.; Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig-Maximilians-Universität, Munich, Germany.; Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Germany., Imboden M; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK., Marten J; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Enroth S; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala Universitet, Uppsala, Sweden., Kerr SM; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Surakka I; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; The National Institute for Health and Welfare (THL), Helsinki, Finland., Vitart V; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Allen RJ; Department of Health Sciences, University of Leicester, Leicester, UK., Bakke PS; Department of Clinical Science, University of Bergen, Bergen, Norway., Beaty TH; Department of Epidemiology, Johns Hopkins University School of Public Health, Baltimore, MD, USA., Bleecker ER; Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, AZ, USA., Bossé Y; Department of Molecular Medicine, Laval University, Québec, Canada.; Institut Universitaire de Cardiologie et de Pneumologie de Québec, Laval University, Québec, Canada., Brandsma CA; University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, GRIAC Research Institute, University of Groningen, Groningen, The Netherlands., Chen Z; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Crapo JD; National Jewish Health, Denver, CO, USA.; Division of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, CO, USA., Danesh J; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Cambridge Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, UK.; Department of Human Genetics, Wellcome Trust Sanger Institute, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., DeMeo DL; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Dudbridge F; Department of Health Sciences, University of Leicester, Leicester, UK., Ewert R; Department of Internal Medicine B - Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Greifswald, Germany., Gieger C; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health, Neuherberg, Germany., Gulsvik A; Department of Clinical Science, University of Bergen, Bergen, Norway., Hansell AL; Centre for Environmental Health & Sustainability, University of Leicester, Leicester, UK.; UK Small Area Health Statistics Unit, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, St Mary's Hospital, London, UK., Hao K; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hoffman JD; Target Sciences, GlaxoSmithKline, Collegeville, PA, USA., Hokanson JE; Department of Epidemiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Joshi PK; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Joubert P; Institut Universitaire de Cardiologie et de Pneumologie de Québec, Laval University, Québec, Canada.; Department of Molecular Biology, Medical Biochemistry, and Pathology, Laval University, Québec, Canada., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Li X; The University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada., Li L; Department of Epidemiology & Biostatistics, Peking University Health Science Center, Beijing, China., Lin K; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Locantore N; GSK R&D, Collegeville, PA, USA., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Maranville JC; MRL, Merck & Co., Inc, Kenilworth, NJ, USA., Murray A; The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK., Nickle DC; MRL, Merck & Co., Inc, Kenilworth, NJ, USA.; Gossamer Bio, San Diego, CA, USA., Packer R; Department of Health Sciences, University of Leicester, Leicester, UK., Parker MM; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Paynton ML; Department of Health Sciences, University of Leicester, Leicester, UK., Porteous DJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK., Prokopenko D; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Qiao D; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Rawal R; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Runz H; MRL, Merck & Co., Inc, Kenilworth, NJ, USA., Sayers I; Division of Respiratory Medicine and NIHR-Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Sin DD; The University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada.; Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Smith BH; Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Artigas MS; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.; Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.; Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Spain., Sparrow D; VA Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Tal-Singer R; GSK R&D, Collegeville, PA, USA., Timmers PRHJ; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Van den Berge M; University of Groningen, University Medical Center Groningen, Department of Pulmonology, GRIAC Research Institute, University of Groningen, Groningen, The Netherlands., Whittaker JC; Target Sciences - R&D, GSK Medicines Research Centre, Stevenage, UK., Woodruff PG; UCSF Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, CA, USA., Yerges-Armstrong LM; Target Sciences, GlaxoSmithKline, Collegeville, PA, USA., Troyanskaya OG; Department of Computer Science, Princeton University, Princeton, NJ, USA.; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Polašek O; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; University of Split School of Medicine, Split, Croatia., Gyllensten U; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala Universitet, Uppsala, Sweden., Rudan I; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Probst-Hensch NM; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Schulz H; Institute of Epidemiology, Helmholtz Zentrum Muenchen-German Research Center for Environmental Health, Neuherberg, Germany.; Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Germany., James AL; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; School of Medicine and Pharmacology, The University of Western Australia, Crawley, Western Australia, Australia., Wilson JF; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Stubbe B; Department of Internal Medicine B - Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Greifswald, Germany., Zeggini E; Wellcome Sanger Institute, Hinxton, UK.; Institute of Translational Genomics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health, Neuherberg, Germany., Jarvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Unit of Primary Health Care, Oulu University Hospital, Oulu, Finland.; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Uxbridge, UK., Wareham N; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Silverman EK; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Scott RA; Target Sciences - R&D, GSK Medicines Research Centre, Stevenage, UK., Walters RG; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Meyers DA; Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, AZ, USA., Cho MH; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Strachan DP; Population Health Research Institute, St George's, University of London, London, UK., Hall IP; Division of Respiratory Medicine and NIHR-Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, UK. mt47@leicester.ac.uk.; National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK. mt47@leicester.ac.uk., Wain LV; Department of Health Sciences, University of Leicester, Leicester, UK. lvw1@leicester.ac.uk.; National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK. lvw1@leicester.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2024 May; Vol. 56 (5), pp. 1032-1033.
Autor:
Burgess S; MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. Electronic address: sb452@medschl.cam.ac.uk., Mason AM; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Grant AJ; MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Slob EAW; MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Gkatzionis A; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Zuber V; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK; UK Dementia Research Institute at Imperial College, Imperial College London, London, UK., Patel A; MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Tian H; MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Liu C; MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Haynes WG; Novo Nordisk Research Centre Oxford, Novo Nordisk, Oxford, UK; Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Hovingh GK; Department of Vascular Medicine, Academic Medical Center, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Global Chief Medical Office, Novo Nordisk, Copenhagen, Denmark., Knudsen LB; Chief Scientific Advisor Office, Research and Early Development, Novo Nordisk, Copenhagen, Denmark., Whittaker JC; MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Gill D; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK; Chief Scientific Advisor Office, Research and Early Development, Novo Nordisk, Copenhagen, Denmark.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2023 Feb 02; Vol. 110 (2), pp. 195-214.
Autor:
Shrine N; Department of Health Sciences, University of Leicester, Leicester, UK., Guyatt AL; Department of Health Sciences, University of Leicester, Leicester, UK., Erzurumluoglu AM; Department of Health Sciences, University of Leicester, Leicester, UK., Jackson VE; Department of Health Sciences, University of Leicester, Leicester, UK.; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Hobbs BD; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Melbourne CA; Department of Health Sciences, University of Leicester, Leicester, UK., Batini C; Department of Health Sciences, University of Leicester, Leicester, UK., Fawcett KA; Department of Health Sciences, University of Leicester, Leicester, UK., Song K; Target Sciences, GlaxoSmithKline, Collegeville, PA, USA., Sakornsakolpat P; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Li X; Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, AZ, USA., Boxall R; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK., Reeve NF; Department of Health Sciences, University of Leicester, Leicester, UK., Obeidat M; The University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada., Zhao JH; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Wielscher M; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health,Imperial College London, London, UK., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Kentistou KA; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Cook JP; Department of Biostatistics, University of Liverpool, Liverpool, UK., Sun BB; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Zhou J; Flatiron Institute, Simons Foundation, New York, NY, USA., Hui J; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; School of Population Health, The University of Western Australia, Crawley, Western Australia, Australia.; PathWest Laboratory Medicine of WA,Sir Charles Gairdner Hospital, Crawley, Western Australia, Australia.; School of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia., Karrasch S; Institute of Epidemiology, Helmholtz Zentrum Muenchen-German Research Center for Environmental Health, Neuherberg, Germany.; Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig-Maximilians-Universität, Munich, Germany.; Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Germany., Imboden M; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK., Marten J; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Enroth S; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala Universitet, Uppsala, Sweden., Kerr SM; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Surakka I; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; The National Institute for Health and Welfare (THL), Helsinki, Finland., Vitart V; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Allen RJ; Department of Health Sciences, University of Leicester, Leicester, UK., Bakke PS; Department of Clinical Science, University of Bergen, Bergen, Norway., Beaty TH; Department of Epidemiology, Johns Hopkins University School of Public Health, Baltimore, MD, USA., Bleecker ER; Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, AZ, USA., Bossé Y; Department of Molecular Medicine, Laval University, Québec, Canada.; Institut Universitaire de Cardiologie et de Pneumologie de Québec,Laval University, Québec, Canada., Brandsma CA; University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, GRIAC Research Institute,University of Groningen, Groningen, The Netherlands., Chen Z; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Crapo JD; National Jewish Health, Denver, CO, USA.; Division of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, CO, USA., Danesh J; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Cambridge Centre of Excellence, Division of Cardiovascular Medicine,Addenbrooke's Hospital, Cambridge, UK.; Department of Human Genetics, Wellcome Trust Sanger Institute, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., DeMeo DL; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Dudbridge F; Department of Health Sciences, University of Leicester, Leicester, UK., Ewert R; Department of Internal Medicine B - Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Greifswald, Germany., Gieger C; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health, Neuherberg, Germany., Gulsvik A; Department of Clinical Science, University of Bergen, Bergen, Norway., Hansell AL; Centre for Environmental Health & Sustainability, University of Leicester, Leicester, UK.; UK Small Area Health Statistics Unit, MRC-PHE Centre for Environment and Health, School of Public Health,Imperial College London, London, UK.; Imperial College Healthcare NHS Trust,St Mary's Hospital, London, UK., Hao K; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hoffman JD; Target Sciences, GlaxoSmithKline, Collegeville, PA, USA., Hokanson JE; Department of Epidemiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Joshi PK; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Joubert P; Institut Universitaire de Cardiologie et de Pneumologie de Québec,Laval University, Québec, Canada.; Department of Molecular Biology, Medical Biochemistry, and Pathology,Laval University, Québec, Canada., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Li X; The University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada., Li L; Department of Epidemiology & Biostatistics, Peking University Health Science Center, Beijing, China., Lin K; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology,Uppsala University, Uppsala, Sweden., Locantore N; GSK R&D, Collegeville, PA, USA., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Maranville JC; MRL, Merck & Co., Inc, Kenilworth, NJ, USA., Murray A; The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK., Nickle DC; MRL, Merck & Co., Inc, Kenilworth, NJ, USA.; Gossamer Bio, San Diego, CA, USA., Packer R; Department of Health Sciences, University of Leicester, Leicester, UK., Parker MM; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Paynton ML; Department of Health Sciences, University of Leicester, Leicester, UK., Porteous DJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK., Prokopenko D; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Qiao D; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Rawal R; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Runz H; MRL, Merck & Co., Inc, Kenilworth, NJ, USA., Sayers I; Division of Respiratory Medicine and NIHR-Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Sin DD; The University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada.; Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Smith BH; Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Artigas MS; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.; Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.; Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Spain., Sparrow D; VA Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Tal-Singer R; GSK R&D, Collegeville, PA, USA., Timmers PRHJ; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Van den Berge M; University of Groningen, University Medical Center Groningen, Department of Pulmonology, GRIAC Research Institute,University of Groningen, Groningen, The Netherlands., Whittaker JC; Target Sciences - R&D, GSK Medicines Research Centre, Stevenage, UK., Woodruff PG; UCSF Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, CA, USA., Yerges-Armstrong LM; Target Sciences, GlaxoSmithKline, Collegeville, PA, USA., Troyanskaya OG; Department of Computer Science, Princeton University, Princeton, NJ, USA.; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences,University of Tampere, Tampere, Finland., Polašek O; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; University of Split School of Medicine, Split, Croatia., Gyllensten U; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala Universitet, Uppsala, Sweden., Rudan I; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Probst-Hensch NM; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Schulz H; Institute of Epidemiology, Helmholtz Zentrum Muenchen-German Research Center for Environmental Health, Neuherberg, Germany.; Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Germany., James AL; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; School of Medicine and Pharmacology, The University of Western Australia, Crawley, Western Australia, Australia., Wilson JF; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Stubbe B; Department of Internal Medicine B - Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Greifswald, Germany., Zeggini E; Wellcome Sanger Institute, Hinxton, UK.; Institute of Translational Genomics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health, Neuherberg, Germany., Jarvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health,Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine,University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Unit of Primary Health Care, Oulu University Hospital, Oulu, Finland.; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Uxbridge, UK., Wareham N; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Silverman EK; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Scott RA; Target Sciences - R&D, GSK Medicines Research Centre, Stevenage, UK., Walters RG; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Meyers DA; Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, AZ, USA., Cho MH; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Strachan DP; Population Health Research Institute, St George's, University of London, London, UK., Hall IP; Division of Respiratory Medicine and NIHR-Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, UK. mt47@leicester.ac.uk.; National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK. mt47@leicester.ac.uk., Wain LV; Department of Health Sciences, University of Leicester, Leicester, UK. lvw1@leicester.ac.uk.; National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK. lvw1@leicester.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2019 Jun; Vol. 51 (6), pp. 1067.
Autor:
Wadsworth CA; Digestive Health Section, Department of Surgery and Cancer, St Mary's Hospital Campus, Imperial College London, London, United Kingdom., Dixon PH; Department of Women and Children's Health, School of Life Course Sciences, Guy's Hospital Campus, King's College London, London, United Kingdom., Taylor-Robinson S; Digestive Health Section, Department of Surgery and Cancer, St Mary's Hospital Campus, Imperial College London, London, United Kingdom., Kim JU; Digestive Health Section, Department of Surgery and Cancer, St Mary's Hospital Campus, Imperial College London, London, United Kingdom., Zabron AA; Digestive Health Section, Department of Surgery and Cancer, St Mary's Hospital Campus, Imperial College London, London, United Kingdom., Wong JH; Digestive Health Section, Department of Surgery and Cancer, St Mary's Hospital Campus, Imperial College London, London, United Kingdom., Chapman MH; Institute for Liver & Digestive Health, Royal Free Hospital Campus, University College London, London, United Kingdom., McKay SC; Surgery Section, Department of Surgery and Cancer, Hammersmith Hospital Campus, Imperial College London, London, United Kingdom., Spalding DR; Surgery Section, Department of Surgery and Cancer, Hammersmith Hospital Campus, Imperial College London, London, United Kingdom., Wasan HS; Oncology Section, Department of Surgery and Cancer, Hammersmith Hospital Campus, Imperial College London, London, United Kingdom., Pereira SP; Institute for Liver & Digestive Health, Royal Free Hospital Campus, University College London, London, United Kingdom., Thomas HC; Digestive Health Section, Department of Surgery and Cancer, St Mary's Hospital Campus, Imperial College London, London, United Kingdom., Whittaker JC; Statistical Platforms and Technologies, Medicines Research Centre, GlaxoSmithKline, Stevenage, Hertfordshire, United Kingdom.; Statistical Genetics Unit, London School of Hygiene and Tropical Medicine, University of London, London, United Kingdom., Williamson C; Department of Women and Children's Health, School of Life Course Sciences, Guy's Hospital Campus, King's College London, London, United Kingdom., Khan SA; Digestive Health Section, Department of Surgery and Cancer, St Mary's Hospital Campus, Imperial College London, London, United Kingdom.
Publikováno v:
Journal of clinical and experimental hepatology [J Clin Exp Hepatol] 2019 Mar-Apr; Vol. 9 (2), pp. 171-175. Date of Electronic Publication: 2018 Jul 20.
Autor:
Shrine N; Department of Health Sciences, University of Leicester, Leicester, UK., Guyatt AL; Department of Health Sciences, University of Leicester, Leicester, UK., Erzurumluoglu AM; Department of Health Sciences, University of Leicester, Leicester, UK., Jackson VE; Department of Health Sciences, University of Leicester, Leicester, UK.; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Hobbs BD; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Melbourne CA; Department of Health Sciences, University of Leicester, Leicester, UK., Batini C; Department of Health Sciences, University of Leicester, Leicester, UK., Fawcett KA; Department of Health Sciences, University of Leicester, Leicester, UK., Song K; Target Sciences, GlaxoSmithKline, Collegeville, PA, USA., Sakornsakolpat P; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Li X; Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, AZ, USA., Boxall R; Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK., Reeve NF; Department of Health Sciences, University of Leicester, Leicester, UK., Obeidat M; The University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada., Zhao JH; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Wielscher M; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, UK., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Kentistou KA; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Cook JP; Department of Biostatistics, University of Liverpool, Liverpool, UK., Sun BB; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Zhou J; Flatiron Institute, Simons Foundation, New York, NY, USA., Hui J; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; School of Population Health, The University of Western Australia, Crawley, Western Australia, Australia.; PathWest Laboratory Medicine of WA, Sir Charles Gairdner Hospital, Crawley, Western Australia, Australia.; School of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia., Karrasch S; Institute of Epidemiology, Helmholtz Zentrum Muenchen-German Research Center for Environmental Health, Neuherberg, Germany.; Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig-Maximilians-Universität, Munich, Germany.; Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Germany., Imboden M; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK., Marten J; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Enroth S; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala Universitet, Uppsala, Sweden., Kerr SM; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Surakka I; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; The National Institute for Health and Welfare (THL), Helsinki, Finland., Vitart V; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Allen RJ; Department of Health Sciences, University of Leicester, Leicester, UK., Bakke PS; Department of Clinical Science, University of Bergen, Bergen, Norway., Beaty TH; Department of Epidemiology, Johns Hopkins University School of Public Health, Baltimore, MD, USA., Bleecker ER; Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, AZ, USA., Bossé Y; Department of Molecular Medicine, Laval University, Québec, Canada.; Institut Universitaire de Cardiologie et de Pneumologie de Québec, Laval University, Québec, Canada., Brandsma CA; University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, GRIAC Research Institute, University of Groningen, Groningen, The Netherlands., Chen Z; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Crapo JD; National Jewish Health, Denver, CO, USA.; Division of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, CO, USA., Danesh J; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Cambridge Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, UK.; Department of Human Genetics, Wellcome Trust Sanger Institute, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., DeMeo DL; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Dudbridge F; Department of Health Sciences, University of Leicester, Leicester, UK., Ewert R; Department of Internal Medicine B - Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Greifswald, Germany., Gieger C; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health, Neuherberg, Germany., Gulsvik A; Department of Clinical Science, University of Bergen, Bergen, Norway., Hansell AL; Centre for Environmental Health & Sustainability, University of Leicester, Leicester, UK.; UK Small Area Health Statistics Unit, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, St Mary's Hospital, London, UK., Hao K; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hoffman JD; Target Sciences, GlaxoSmithKline, Collegeville, PA, USA., Hokanson JE; Department of Epidemiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Joshi PK; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Joubert P; Institut Universitaire de Cardiologie et de Pneumologie de Québec, Laval University, Québec, Canada.; Department of Molecular Biology, Medical Biochemistry, and Pathology, Laval University, Québec, Canada., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Li X; The University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada., Li L; Department of Epidemiology & Biostatistics, Peking University Health Science Center, Beijing, China., Lin K; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Locantore N; GSK R&D, Collegeville, PA, USA., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Maranville JC; MRL, Merck & Co., Inc, Kenilworth, NJ, USA., Murray A; The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK., Nickle DC; MRL, Merck & Co., Inc, Kenilworth, NJ, USA.; Gossamer Bio, San Diego, CA, USA., Packer R; Department of Health Sciences, University of Leicester, Leicester, UK., Parker MM; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Paynton ML; Department of Health Sciences, University of Leicester, Leicester, UK., Porteous DJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK., Prokopenko D; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Qiao D; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Rawal R; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Runz H; MRL, Merck & Co., Inc, Kenilworth, NJ, USA., Sayers I; Division of Respiratory Medicine and NIHR-Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Sin DD; The University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada.; Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Smith BH; Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Soler Artigas M; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.; Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.; Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Spain., Sparrow D; VA Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Tal-Singer R; GSK R&D, Collegeville, PA, USA., Timmers PRHJ; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Van den Berge M; University of Groningen, University Medical Center Groningen, Department of Pulmonology, GRIAC Research Institute, University of Groningen, Groningen, The Netherlands., Whittaker JC; Target Sciences - R&D, GSK Medicines Research Centre, Stevenage, UK., Woodruff PG; UCSF Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, CA, USA., Yerges-Armstrong LM; Target Sciences, GlaxoSmithKline, Collegeville, PA, USA., Troyanskaya OG; Department of Computer Science, Princeton University, Princeton, NJ, USA.; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Polašek O; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; University of Split School of Medicine, Split, Croatia., Gyllensten U; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala Universitet, Uppsala, Sweden., Rudan I; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Probst-Hensch NM; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Schulz H; Institute of Epidemiology, Helmholtz Zentrum Muenchen-German Research Center for Environmental Health, Neuherberg, Germany.; Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Germany., James AL; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; School of Medicine and Pharmacology, The University of Western Australia, Crawley, Western Australia, Australia., Wilson JF; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Stubbe B; Department of Internal Medicine B - Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Greifswald, Germany., Zeggini E; Wellcome Sanger Institute, Hinxton, UK.; Institute of Translational Genomics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health, Neuherberg, Germany., Jarvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Unit of Primary Health Care, Oulu University Hospital, Oulu, Finland.; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Uxbridge, UK., Wareham N; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Silverman EK; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Scott RA; Target Sciences - R&D, GSK Medicines Research Centre, Stevenage, UK., Walters RG; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Meyers DA; Division of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, AZ, USA., Cho MH; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Strachan DP; Population Health Research Institute, St George's, University of London, London, UK., Hall IP; Division of Respiratory Medicine and NIHR-Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, UK. mt47@leicester.ac.uk.; National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK. mt47@leicester.ac.uk., Wain LV; Department of Health Sciences, University of Leicester, Leicester, UK. lvw1@leicester.ac.uk.; National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK. lvw1@leicester.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2019 Mar; Vol. 51 (3), pp. 481-493. Date of Electronic Publication: 2019 Feb 25.
Autor:
Nüesch E; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.; CTU Bern, Department of Clinical Research and Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland., Dale C; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK., Palmer TM; Warwick Medical School, University of Warwick, Coventry, UK.; Department of Mathematics and Statistics, Lancaster University, Lancaster, UK., White J; UCL Genetics Institute, Department of Genetics, Evolution and Environment, University College London, London, UK., Keating BJ; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Surgery.; Division of Genetics, University of Pennsylvania, Philadelphia., van Iperen EP; Department of Biostatistics, Academic Medical Center Amsterdam, Amsterdam, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands., Goel A; Wellcome Trust Centre for Human Genetics and Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Asselbergs FW; Department of Cardiology, Division Heart and Lungs, University Medical Centre Utrecht, Utrecht, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK., Verschuren WM, Wijmenga C, Van der Schouw YT, Onland-Moret NC; EPIC-NL, Bilthoven and Utrecht, The Netherlands., Lange LA; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Hovingh GK; Department of Vascular Medicine, Academic Medical Center Amsterdam, Amsterdam, The Netherlands., Sivapalaratnam S; Department of Vascular Medicine, Academic Medical Center Amsterdam, Amsterdam, The Netherlands., Morris RW; Department of Primary Care & Population Health, University College London, London, UK., Whincup PH; Population Health Research Institute, St George's, University of London, London, UK., Wannamethe GS; Department of Primary Care & Population Health, University College London, London, UK., Gaunt TR; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.; School of Social and Community Medicine, University of Bristol, Bristol, UK., Ebrahim S; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK., Steel L; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Nair N; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA, USA / Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Wilson JF; Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Bolton JL; Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., McLachlan S; Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Price JF; Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Strachan MW; Metabolic Unit, Western General Hospital, Edinburgh, UK., Robertson CM; Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Kleber ME; Fifth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany., Delgado G; Fifth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany., März W; Medical Clinic V (Nephrology, Hypertensiology, Endocrinology, Diabetolgy, and Rheumatology), Mannheim Medical Faculty, University of Heidelberg, Germany, Synlab Academy, Synlab Services GmbH, Mannheim and Augsburg, Germany, Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Austria., Melander O; Lund University, Sweden., Dominiczak AF; Institute of Cardiovascular and Medical Sciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Farrall M; Wellcome Trust Centre for Human Genetics and Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Watkins H; Wellcome Trust Centre for Human Genetics and Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Leusink M; Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands., Maitland-van der Zee AH; Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., de Groot MC; Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands., Dudbridge F; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK., Hingorani A; Department of Epidemiology and Public Health, University College London Medical School, London, UK., Ben-Shlomo Y; School of Social and Community Medicine, University of Bristol, Bristol, UK., Lawlor DA; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.; School of Social and Community Medicine, University of Bristol, Bristol, UK., Amuzu A, Caufield M, Cavadino A, Cooper J, Davies TL, Drenos F, Engmann J, Finan C, Giambartolomei C, Hardy R, Humphries SE, Hypponen E, Kivimaki M, Kuh D, Kumari M, Ong K, Plagnol V, Power C, Richards M, Shah S, Shah T, Sofat R, Talmud PJ, Wareham N, Warren H, Whittaker JC, Wong A, Zabaneh D; UCLEB, London, Edinburgh and Bristol, UK., Davey Smith G; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.; School of Social and Community Medicine, University of Bristol, Bristol, UK., Wells JC; Childhood Nutrition Research Centre, UCL Institute of Child Health, London, UK., Leon DA; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.; Department of Community Medicine, Arctic University of Norway, UiT., Holmes MV; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.; Department of Surgery and Clinical Epidemiology Unit, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK., Casas JP; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK.
Publikováno v:
International journal of epidemiology [Int J Epidemiol] 2016 Dec 01; Vol. 45 (6), pp. 1927-1937.
Autor:
Swerdlow DI; Institute of Cardiovascular Science, University College London, London, UK d.swerdlow@ucl.ac.uk.; Department of Medicine, Imperial College London, London, UK., Kuchenbaecker KB; Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Shah S; Institute of Cardiovascular Science, University College London, London, UK., Sofat R; Institute of Cardiovascular Science, University College London, London, UK.; Centre for Clinical Pharmacology and Therapeutics, University College London, London, UK., Holmes MV; Institute of Cardiovascular Science, University College London, London, UK.; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, Oxford, UK., White J; Institute of Cardiovascular Science, University College London, London, UK., Mindell JS; Research Department of Epidemiology & Public Health, University College London, London, UK., Kivimaki M; Research Department of Epidemiology & Public Health, University College London, London, UK., Brunner EJ; Research Department of Epidemiology & Public Health, University College London, London, UK., Whittaker JC; Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.; Genetics Division, Research and Development, GlaxoSmithKline, NFSP, Harlow, UK., Casas JP; Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK., Hingorani AD; Institute of Cardiovascular Science, University College London, London, UK.
Publikováno v:
International journal of epidemiology [Int J Epidemiol] 2016 Oct; Vol. 45 (5), pp. 1600-1616. Date of Electronic Publication: 2016 Jun 24.
Autor:
White J; UCL Genetics Institute, University College, London, UK. Electronic address: jon.white@ucl.ac.uk., Sofat R; Centre for Clinical Pharmacology, University College London, London, UK., Hemani G; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK., Shah T; Institute of Cardiovascular Science and Farr Institute, University College London, London, UK., Engmann J; Institute of Cardiovascular Science and Farr Institute, University College London, London, UK., Dale C; Department of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK., Shah S; Queensland Brain Institute, University of Queensland, QLD, Australia., Kruger FA; Institute of Cardiovascular Science and Farr Institute, University College London, London, UK., Giambartolomei C; UCL Genetics Institute, University College, London, UK., Swerdlow DI; Institute of Cardiovascular Science and Farr Institute, University College London, London, UK., Palmer T; Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK., McLachlan S; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK., Langenberg C; Institute of Cardiovascular Science and Farr Institute, University College London, London, UK; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Zabaneh D; UCL Genetics Institute, University College, London, UK., Lovering R; Centre for Cardiovascular Genetics, British Heart Foundation Laboratories, Institute of Cardiovascular Science, University College London, London, UK., Cavadino A; Population, Policy and Practice, UCL Institute of Child Health, University College London, London, UnK., Jefferis B; Department of Primary Care & Population Health, University College London, Royal Free Campus, London, UK., Finan C; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Wong A; MRC Unit for Lifelong Health and Ageing at UCL, London, UK., Amuzu A; Department of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK., Ong K; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK; MRC Unit for Lifelong Health and Ageing at UCL, London, UK., Gaunt TR; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK; School of Social and Community Medicine, University of Bristol, Bristol, UK., Warren H; Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Denstistry, Queen Mary University of London, London, UK; NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, UK., Davies TL; School of Social and Community Medicine, University of Bristol, Bristol, UK., Drenos F; Centre for Cardiovascular Genetics, British Heart Foundation Laboratories, Institute of Cardiovascular Science, University College London, London, UK; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK., Cooper J; Centre for Cardiovascular Genetics, British Heart Foundation Laboratories, Institute of Cardiovascular Science, University College London, London, UK., Ebrahim S; Department of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK., Lawlor DA; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK., Talmud PJ; Centre for Cardiovascular Genetics, British Heart Foundation Laboratories, Institute of Cardiovascular Science, University College London, London, UK., Humphries SE; Centre for Cardiovascular Genetics, British Heart Foundation Laboratories, Institute of Cardiovascular Science, University College London, London, UK., Power C; Population, Policy and Practice, UCL Institute of Child Health, University College London, London, UnK., Hypponen E; Population, Policy and Practice, UCL Institute of Child Health, University College London, London, UnK; School of Population Health and Sansom Institute of Health Research, University of South Australia, Adelaide, SA, Australia; South Australian Health and Medical Research Institute, Adelaide, SA, Australia., Richards M; MRC Unit for Lifelong Health and Ageing at UCL, London, UK., Hardy R; MRC Unit for Lifelong Health and Ageing at UCL, London, UK., Kuh D; MRC Unit for Lifelong Health and Ageing at UCL, London, UK., Wareham N; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Ben-Shlomo Y; School of Social and Community Medicine, University of Bristol, Bristol, UK., Day IN; School of Social and Community Medicine, University of Bristol, Bristol, UK., Whincup P; Population Health Research Institute, St George's, University of London, London, UK., Morris R; Department of Primary Care & Population Health, University College London, Royal Free Campus, London, UK., Strachan MW; Metabolic Unit, Western General Hospital, Edinburgh, UK., Price J; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK., Kumari M; Institute for Social and Economic Research, University of Essex, Colchester, UK., Kivimaki M; Department of Epidemiology & Public Health, UCL Institute of Epidemiology & Health Care, University College London, London, UK., Plagnol V; UCL Genetics Institute, University College, London, UK., Whittaker JC; Genetics Division, Research and Development, GlaxoSmithKline, Harlow, UK., Smith GD; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK., Dudbridge F; Department of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK., Casas JP; Department of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK; Institute of Cardiovascular Science and Farr Institute, University College London, London, UK., Holmes MV; Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK; Department of Surgery and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: michael.holmes@ndph.ox.ac.uk., Hingorani AD; Institute of Cardiovascular Science and Farr Institute, University College London, London, UK.
Publikováno v:
The lancet. Diabetes & endocrinology [Lancet Diabetes Endocrinol] 2016 Apr; Vol. 4 (4), pp. 327-36. Date of Electronic Publication: 2016 Jan 16.
Autor:
Nelson MR; Quantitative Sciences, GlaxoSmithKline, Research Triangle Park, North Carolina, USA., Tipney H; Quantitative Sciences, GlaxoSmithKline, Stevenage, UK., Painter JL; Quantitative Sciences, GlaxoSmithKline, Research Triangle Park, North Carolina, USA., Shen J; Quantitative Sciences, GlaxoSmithKline, Research Triangle Park, North Carolina, USA., Nicoletti P; Department of Systems Biology, Columbia University, New York, New York, USA., Shen Y; 1] Department of Systems Biology, Columbia University, New York, New York, USA. [2] Department of Biomedical Informatics, Columbia University, New York, New York, USA., Floratos A; 1] Department of Systems Biology, Columbia University, New York, New York, USA. [2] Department of Biomedical Informatics, Columbia University, New York, New York, USA., Sham PC; 1] State Key Laboratory of Brain and Cognitive Sciences, University of Hong Kong, Hong Kong, SAR, China. [2] Centre for Genomics Sciences, Li Ka Shing (LKS) Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China., Li MJ; 1] Centre for Genomics Sciences, Li Ka Shing (LKS) Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China. [2] Department of Biochemistry, LKS Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China., Wang J; 1] Centre for Genomics Sciences, Li Ka Shing (LKS) Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China. [2] Department of Biochemistry, LKS Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China., Cardon LR; Alternative Discovery and Development, GlaxoSmithKline, Upper Merion, Pennsylvania, USA., Whittaker JC; Quantitative Sciences, GlaxoSmithKline, Stevenage, UK., Sanseau P; Quantitative Sciences, GlaxoSmithKline, Stevenage, UK.
Publikováno v:
Nature genetics [Nat Genet] 2015 Aug; Vol. 47 (8), pp. 856-60. Date of Electronic Publication: 2015 Jun 29.