Zobrazeno 1 - 10 of 94 pro vyhledávání: '"Jb, Harford"'
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The iron-responsive element is the single element responsible for iron-dependent translational regulation of ferritin biosynthesis. Evidence for function as the binding site for a translational repressor
Autor: Sw, Caughman, Matthias Hentze, Ta, Rouault, Jb, Harford, Rd, Klausner
Publikováno v: EMBL-EBI
Ferritin, a cytoplasmic protein critical in iron metabolism, displays iron-dependent regulation of its biosynthetic rate with no corresponding changes in mRNA levels. An iron-responsive element (IRE) has been identified in the 5'-untranslated region
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::220040039698f4c93bb0a24d52e96649
https://pubmed.ncbi.nlm.nih.gov/3198610
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2
Akademický článek
scL-2PAM: A Novel Countermeasure That Ameliorates Neuroinflammation and Neuronal Losses in Mice Exposed to an Anticholinesterase Organophosphate.
Autor: Moghe M; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA., Kim SS; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, Washington, DC 20057, USA.; SynerGene Therapeutics, Inc., Potomac, MD 20854, USA., Guan M; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA., Rait A; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA., Pirollo KF; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA., Harford JB; SynerGene Therapeutics, Inc., Potomac, MD 20854, USA., Chang EH; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, Washington, DC 20057, USA.
Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 09; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 09.
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3
Akademický článek
SMARCB1 Gene Therapy Using a Novel Tumor-Targeted Nanomedicine Enhances Anti-Cancer Efficacy in a Mouse Model of Atypical Teratoid Rhabdoid Tumors.
Autor: Kim SS; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.; SynerGene Therapeutics, Inc, Potomac, MD, USA., Moghe M; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA., Rait A; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA., Donaldson K; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA., Harford JB; SynerGene Therapeutics, Inc, Potomac, MD, USA., Chang EH; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.
Publikováno v: International journal of nanomedicine [Int J Nanomedicine] 2024 Jun 14; Vol. 19, pp. 5973-5993. Date of Electronic Publication: 2024 Jun 14 (Print Publication: 2024).
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4
Akademický článek
A Pralidoxime Nanocomplex Formulation Targeting Transferrin Receptors for Reactivation of Brain Acetylcholinesterase After Exposure of Mice to an Anticholinesterase Organophosphate.
Autor: Pirollo KF; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, 20057, USA., Moghe M; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, 20057, USA., Guan M; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, 20057, USA., Rait AS; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, 20057, USA., Wang A; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, 20057, USA., Kim SS; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, 20057, USA.; SynerGene Therapeutics, Inc., Potomac, MD, 20854, USA., Chang EH; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, 20057, USA., Harford JB; SynerGene Therapeutics, Inc., Potomac, MD, 20854, USA.
Publikováno v: International journal of nanomedicine [Int J Nanomedicine] 2024 Jan 12; Vol. 19, pp. 307-326. Date of Electronic Publication: 2024 Jan 12 (Print Publication: 2024).
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5
Akademický článek
A Second Career for p53 as A Broad-Spectrum Antiviral?
Autor: Harford JB; SynerGene Therapeutics, Inc., Potomac, MD 20854, USA.
Publikováno v: Viruses [Viruses] 2023 Dec 03; Vol. 15 (12). Date of Electronic Publication: 2023 Dec 03.
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6
Akademický článek
A Novel P53 Nanomedicine Reduces Immunosuppression and Augments Anti-PD-1 Therapy for Non-Small Cell Lung Cancer in Syngeneic Mouse Models.
Autor: Kim SS; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.; SynerGene Therapeutics, Inc., Potomac, MD 20854, USA., Harford JB; SynerGene Therapeutics, Inc., Potomac, MD 20854, USA., Moghe M; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA., Doherty C; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.; College of Medicine and Science, Mayo Clinic, Rochester, MN 55905, USA., Chang EH; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.
Publikováno v: Cells [Cells] 2022 Oct 31; Vol. 11 (21). Date of Electronic Publication: 2022 Oct 31.
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7
Akademický článek
Nanomedicine-Based Gene Delivery for a Truncated Tumor Suppressor RB94 Promotes Lung Cancer Immunity.
Autor: Kim SS; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.; SynerGene Therapeutics, Inc., Potomac, MD 20854, USA., Doherty C; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.; College of Medicine and Science, Mayo Clinic, Rochester, MN 55905, USA., Moghe M; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA., Rait A; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA., Pirollo KF; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA., Harford JB; SynerGene Therapeutics, Inc., Potomac, MD 20854, USA., Chang EH; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.
Publikováno v: Cancers [Cancers (Basel)] 2022 Oct 18; Vol. 14 (20). Date of Electronic Publication: 2022 Oct 18.
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8
Akademický článek
TP53 Gene Therapy as a Potential Treatment for Patients with COVID-19.
Autor: Harford JB; SynerGene Therapeutics, Inc., Potomac, MD 20854, USA., Kim SS; SynerGene Therapeutics, Inc., Potomac, MD 20854, USA.; Department of Oncology, Georgetown University Medical Center, Washington, DC 20007, USA., Pirollo KF; Department of Oncology, Georgetown University Medical Center, Washington, DC 20007, USA., Chang EH; Department of Oncology, Georgetown University Medical Center, Washington, DC 20007, USA.
Publikováno v: Viruses [Viruses] 2022 Mar 31; Vol. 14 (4). Date of Electronic Publication: 2022 Mar 31.
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9
Akademický článek
A tumor-targeting nanomedicine carrying the p53 gene crosses the blood-brain barrier and enhances anti-PD-1 immunotherapy in mouse models of glioblastoma.
Autor: Kim SS; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC.; SynerGene Therapeutics, Inc., Potomac, MD., Harford JB; SynerGene Therapeutics, Inc., Potomac, MD., Moghe M; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC., Slaughter T; SynerGene Therapeutics, Inc., Potomac, MD., Doherty C; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC., Chang EH; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC.
Publikováno v: International journal of cancer [Int J Cancer] 2019 Nov 01; Vol. 145 (9), pp. 2535-2546. Date of Electronic Publication: 2019 Jul 08.
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10
Akademický článek
Advancing Cancer Research in Africa Through Early-Career Awards: The BIG Cat Initiative.
Autor: Vogel AL; Frederick National Laboratory for Cancer Research, Frederick, MD., Freeman JA; National Cancer Institute, Rockville, MD., Duncan K; National Cancer Institute, Rockville, MD., Alaro J; National Cancer Institute, Rockville, MD., Welch JJ; National Cancer Institute, Rockville, MD., Rodrigues B; African Organization for Research and Training in Cancer, New York, NY., Vanderpuye V; African Organization for Research and Training in Cancer, New York, NY., Harford JB; Capacity Building for Innovation and Transformation, Potomac, MD., Williams M; National Institute of Mental Health, Bethesda, MD.
Publikováno v: Journal of global oncology [J Glob Oncol] 2019 Apr; Vol. 5, pp. 1-8.
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