Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jayvee R. Abella"'
Autor:
Erika R. O’Neil, MD, Huiming Lin, MS, Meng Li, PhD, Lara Shekerdemian, MD, Joseph E. Tonna, MD, MS, Ryan P. Barbaro, MD, Jayvee R. Abella, PhD, Peter Rycus, MPH, Graeme MacLaren, MBBS, MSc, Marc M. Anders, MD, Peta M. A. Alexander, MBBS
Publikováno v:
Critical Care Explorations, Vol 3, Iss 12, p e0598 (2021)
OBJECTIVES:. Although there is a substantial published experience of extracorporeal membrane oxygenation during the H1N1 pandemic, less is known about the use of extracorporeal membrane oxygenation in patients with other subtypes of the influenza A v
Externí odkaz:
https://doaj.org/article/08631d11dde44b08a6600bb2ccf818b7
Autor:
Thais Arns, Dinler A. Antunes, Jayvee R. Abella, Maurício M. Rigo, Lydia E. Kavraki, Silvana Giuliatti, Eduardo A. Donadi
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
HLA-G is considered to be an immune checkpoint molecule, a function that is closely linked to the structure and dynamics of the different HLA-G isoforms. Unfortunately, little is known about the structure and dynamics of these isoforms. For instance,
Externí odkaz:
https://doaj.org/article/77aa87bc160e43bbb57e70c810af60ec
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Prediction of stable peptide binding to Class I HLAs is an important component for designing immunotherapies. While the best performing predictors are based on machine learning algorithms trained on peptide-HLA (pHLA) sequences, the use of structure
Externí odkaz:
https://doaj.org/article/2aa4c6caeb2b4ad38938b142fb83a03e
Publikováno v:
Molecules, Vol 24, Iss 5, p 881 (2019)
The Class I Major Histocompatibility Complex (MHC) is a central protein in immunology as it binds to intracellular peptides and displays them at the cell surface for recognition by T-cells. The structural analysis of bound peptide-MHC complexes (pMHC
Externí odkaz:
https://doaj.org/article/99302110cc5840bc8a4113613b22480d
Autor:
Ryan L, Melvin, Jayvee R, Abella, Raajen, Patel, Joshua M, Hagood, Dan E, Berkowitz, Domagoj, Mladinov
Publikováno v:
British Journal of Anaesthesia. 128:e217-e219
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ce24c3d9daabffc9f7ff347d3a218b
https://doi.org/10.1016/j.bja.2021.10.035
https://doi.org/10.1016/j.bja.2021.10.035
Autor:
Kyle R Jackson, Dinler A Antunes, Amjad H Talukder, Ariana R Maleki, Kano Amagai, Avery Salmon, Arjun S Katailiha, Yulun Chiu, Romanos Fasoulis, Maurício Menegatti Rigo, Jayvee R Abella, Brenda D Melendez, Fenge Li, Yimo Sun, Heather M Sonnemann, Vladislav Belousov, Felix Frenkel, Sune Justesen, Aman Makaju, Yang Liu, David Horn, Daniel Lopez-Ferrer, Andreas F Huhmer, Patrick Hwu, Jason Roszik, David Hawke, Lydia E Kavraki, Gregory Lizée
Publikováno v:
PNAS nexus. 1(3)
Human leukocyte antigen class I (HLA-I) molecules bind and present peptides at the cell surface to facilitate the induction of appropriate CD8+ T cell-mediated immune responses to pathogen- and self-derived proteins. The HLA-I peptide-binding cleft c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbae6063ebd0311302efc9db099ae6ed
https://pubmed.ncbi.nlm.nih.gov/36003074
https://pubmed.ncbi.nlm.nih.gov/36003074
Autor:
Joseph E. Tonna, Meng Li, Erika R O'Neil, Jayvee R. Abella, Ryan P. Barbaro, Peta M. A. Alexander, Lara S. Shekerdemian, Peter Rycus, Huiming Lin, Graeme MacLaren, Marc Anders
Background: While there is substantial published experience of ECMO during the H1N1 pandemic, less is known about the use of ECMO in patients with seasonal influenza A virus. We hypothesized that the severity of illness and survival of patients suppo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80ddd7157af4cf328923828a10605a25
https://doi.org/10.21203/rs.3.rs-647294/v1
https://doi.org/10.21203/rs.3.rs-647294/v1
Autor:
Jayvee R. Abella, Dinler A. Antunes, Didier Devaurs, Lydia E. Kavraki, Maurício Menegatti Rigo
Publikováno v:
Current Topics in Medicinal Chemistry. 18:2239-2255
Understanding the mechanisms involved in the activation of an immune response is essential to many fields in human health, including vaccine development and personalized cancer immunotherapy. A central step in the activation of the adaptive immune re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de275be04c288f05d5acfcb5f1fd467
https://doi.org/10.2174/1568026619666181224101744
https://doi.org/10.2174/1568026619666181224101744
Autor:
Jayvee R. Abella, Dinler A. Antunes, Cecilia Clementi, Gregory Lizée, Lydia E. Kavraki, Kyle R. Jackson
Publikováno v:
Proceedings of the National Academy of Sciences
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Peptide binding to major histocompatibility complexes (MHCs) is a central component of the immune system, and understanding the mechanism behind stable peptide-MHC binding will aid the development of immunotherapies. While MHC binding is mostly influ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1448a341bd972ec2faa694bba5195c4
Autor:
Gregory Lizée, Lydia E. Kavraki, Anja Conev, Didier Devaurs, Jayvee R. Abella, Dinler A. Antunes, Sarah Hall-Swan, Mark Moll
Publikováno v:
JCO Clinical Cancer Informatics
PURPOSE HLA protein receptors play a key role in cellular immunity. They bind intracellular peptides and display them for recognition by T-cell lymphocytes. Because T-cell activation is partially driven by structural features of these peptide-HLA com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0a59837b989eda53653b3fff52d69a
http://europepmc.org/articles/PMC7397777
http://europepmc.org/articles/PMC7397777