Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jayson W. Jay"'
Autor:
Kevin DeSpain, Charles R. Rosenfeld, Ryan Huebinger, Xiaofu Wang, Jayson W. Jay, Ravi S. Radhakrishnan, Steven E. Wolf, Juquan Song
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Severe burns result in cardiovascular dysfunction, but responses in the peripheral vasculature are unclear. We hypothesize that severe burns disturb arterial contractility through acute changes in adrenergic and cholinergic receptor function
Externí odkaz:
https://doaj.org/article/68cdfd1fdca14e978a1fbb0f617ea222
Autor:
Alen Palackic, Jayson W. Jay, Robert P. Duggan, Ludwik K. Branski, Steven E. Wolf, Naseem Ansari, Amina El Ayadi
Publikováno v:
Medicina, Vol 58, Iss 7, p 922 (2022)
Burn wound conversion refers to the phenomenon whereby superficial burns that appear to retain the ability to spontaneously heal, convert later into deeper wounds in need of excision. While no current treatment can definitively stop burn wound conver
Externí odkaz:
https://doaj.org/article/b47ec97d6d9f40a7a2e10650ece53b74
Autor:
Joshua M. Peterson, Jayson W. Jay, Ye Wang, Alejandro A. Joglar, Anesh Prasai, Alen Palackic, Steven E. Wolf, Amina El Ayadi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6689 (2022)
Dermal fibroblasts in pathological scars secrete constitutively elevated levels of TGF-β, signaling the transcription of fibrotic genes via activin-like kinase 5 (ALK5). In the present study, we examine the antifibrotic effects of galunisertib, a sm
Externí odkaz:
https://doaj.org/article/9af2dd703e7d4f6b80096df772c628c4
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1105 (2020)
Cutaneous fibrosis results from suboptimal wound healing following significant tissue injury such as severe burns, trauma, and major surgeries. Pathologic skin fibrosis results in scars that are disfiguring, limit normal movement, and prevent patient
Externí odkaz:
https://doaj.org/article/5c67f464f76b47168ea249b04194980d
Autor:
Celeste C. Finnerty, Michael Wetzel, Anesh Prasai, Jayson W. Jay, Robert P. Clayton, David N. Herndon, Ashley N. Guillory, Amina El Ayadi
Publikováno v:
Journal of Surgical Research. 232:154-159
Background It has been previously shown that anesthesia and analgesia can affect outcomes in the rat burn model and that buprenorphine alleviated pain without drastically altering the outcomes of interest. Recently, the use of a sustained release (SR
Publikováno v:
Journal of Burn Care & Research. 43:S67-S67
Introduction Severe burn disrupts cardiovascular function which can lead to critical shock. To counteract cardiovascular collapse, there is a systemic increase of catecholamines released in response to severe burn. Previous studies showed that β1- a
Publikováno v:
J Invest Dermatol
Cell-based therapy imparts its therapeutic effects via soluble growth factors and vesicular bodies like exosomes. A systematic review with a meta-analysis of pre-clinical studies was conducted following the Preferred Reporting Items for Systematic Re
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1105 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Cutaneous fibrosis results from suboptimal wound healing following significant tissue injury such as severe burns, trauma, and major surgeries. Pathologic skin fibrosis results in scars that are disfiguring, limit normal movement, and prevent patient
Autor:
Fredrick J. Bohanon, Nisha Bhattarai, Tracy Toliver-Kinsky, Anesh Prasai, Ravi S. Radhakrishnan, Xiaofu Wang, Amina El Ayadi, Jayson W. Jay, Yesenia Rojas-Khalil, Craig Porter, David N. Herndon, Celeste C. Finnerty, Omar Nunez Lopez
Publikováno v:
Shock. 49:466-473
BACKGROUND A complete understanding of the role of the liver in burn-induced hypermetabolism is lacking. We investigated the acute effect of severe burn trauma on liver mitochondrial respiratory capacity and coupling control as well as the signaling
Autor:
Amina El Ayadi, Ye Wang, Jayson W. Jay, Emre Vardarli, Nisha Bhattarai, Juquan Song, Anesh Prasai, Steven E. Wolf, Victoria G. Rontoyanni
Publikováno v:
Journal of Burn Care & Research. 42:S94-S94
Introduction Severe burns result in decreased skeletal muscle mass and function. Recent evidence suggests that massive burns disrupt the motor-neural system including motor neurons to partially explain skeletal muscle dysfunction in response to burns