Výsledky vyhledávání - "Jayson C. Schalk"

Chronic oral administration of a novel estrogen receptor beta agonist enhances memory consolidation and alleviates vasomotor symptoms in a mouse model of menopause

Autor: Jayson C. Schalk, Karyn M. Frick, Edward A. Wetzel, Aaron W. Fleischer, William A. Donaldson, Alicia M. Hanson, Daniel S. Sem

Publikováno v: Alzheimer's & Dementia. 16

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72b4d2fc6b890293db8573cca799a6d2
https://doi.org/10.1002/alz.047645

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Dorsal Hippocampal Actin Polymerization Is Necessary for Activation of G-Protein-Coupled Estrogen Receptor (GPER) to Increase CA1 Dendritic Spine Density and Enhance Memory Consolidation

Autor: Rachel L. Gremminger, Jayson C. Schalk, Wendy A. Koss, Karyn M. Frick, Jaekyoon Kim, Lisa R. Taxier, Kellie S. Gross

Publikováno v: J Neurosci

Activation of the membrane estrogen receptor G-protein-coupled estrogen receptor (GPER) in ovariectomized mice via the GPER agonist G-1 mimics the beneficial effects of 17β-estradiol (E2) on hippocampal CA1 spine density and memory consolidation, ye

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822dac43741f934a60cbe943be51f779
https://europepmc.org/articles/PMC6880457/

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Long-term oral administration of a novel estrogen receptor beta agonist enhances memory and alleviates drug-induced vasodilation in young ovariectomized mice

Autor: Alicia M. Hanson, Edward A. Wetzel, Karyn M. Frick, Aaron W. Fleischer, Jayson C. Schalk, William A. Donaldson, Daniel S. Sem

Publikováno v: Hormones and behavior

Development of estrogen therapies targeting the β (ERβ) but not α (ERα) estrogen receptor is critically needed for the treatment of negative menopausal symptoms, as ERα activation increases health risks like cancer. Here, we determined the effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be8c0f8c0e5a778e97baf5beda18b91
https://doi.org/10.1016/j.yhbeh.2021.104948

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Chemogenetic Suppression of Medial Prefrontal-Dorsal Hippocampal Interactions Prevents Estrogenic Enhancement of Memory Consolidation in Female Mice

Autor: Jayson C. Schalk, Karyn M. Frick, Jacqueline M. Haertel, Lisa R. Taxier, Jennifer J. Tuscher

Publikováno v: eNeuro

Visual Abstract
The importance of the dorsal hippocampus (DH) in mediating the memory-enhancing effects of the sex-steroid hormone 17β-estradiol (E2) is well established. However, estrogen receptors (ERs) are highly expressed in other brain reg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4376bff1f94c53d0bdf5d3f907aab47
https://pubmed.ncbi.nlm.nih.gov/31016230

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