Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jayson Bowers"'
Autor:
Bill Lauzier, Bruce Walsh, Don Straus, Sadanand Gite, Alejandra Garces, Andrew Tempesta, Ann Zuniga, Jayson Bowers, Adam Williams, Selina Clancy, Jennifer Hickey, Yismel Rosario
Publikováno v:
Infection Control & Hospital Epidemiology. 41:s450-s451
Background:Clostridiodes difficile infection is considered an urgent antibiotic resistance threat by the CDC, accounting for ∼225,000 hospitalizations, 12,800 deaths, and ∼$1 billion in healthcare costs in the United States in 2017. The presence
Autor:
Victoria Dorich, James E. Kirby, David Cunha, Destiny Archambault, Sadanand Gite, Andrew Tempesta, Jessica A. Walsh, Michael Cappillino, Jayson Bowers, Tatyana Shatova, Don Straus, Adam Williams, Bruce Walsh
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Scientific Reports
Scientific Reports
We describe a new rapid and accurate immunoassay-based technology capable of counting single target molecules using digital imaging without magnification. Using the technology, we developed a rapid test for Clostridium difficile toxin B, which is res
Autor:
Michael Sandor Koeris, Ed Tekeian, Paulina Kocjan, Robert P. Shivers, Erin Crowley, Joe Benzinger, Kiel Fisher, Patrick Bird, Jayson Bowers, Andrew Tempesta, Daniel Robert Brownell, Michael Cappillino, John King, Beck E. Jacobson
Publikováno v:
Journal of AOAC International. 98(2)
Publikováno v:
Trends in Biotechnology. 31:325-327
Synthetic biology is an emerging engineering field focused on designing artificial biological systems with novel functionalities for use in therapeutics, basic science, biotechnology, and diagnostics [1,2]. Continuous advancements in DNA synthesis an
Publikováno v:
Journal of Molecular Biology. 302:327-338
The yeast MSH2-MSH6 complex is required to repair both base-pair and single base insertion/deletion mismatches. MSH2-MSH6 binds to mismatch substrates and displays an ATPase activity that is modulated by mispairs that are repaired in vivo. To underst
Autor:
Jayson Bowers1, Mitchell, Judith1, Beer, Eric1, Buzby, Philip R.1, Causey, Marie1, Efcavitch, J. William1, Jarosz, Mirna1, Krzymanska-Olejnik, Edyta1, Li Kung1, Lipson, Doron1, Lowman, Geoffrey M.1, Marappan, Subramanian1, McInerney, Peter1, Platt, Adam1, Roy, Atanu1, Siddiqi, Suhaib M.1, Steinmann, Kathleen1, Thompson, John F.1 jthompson@helicosbio.com
Publikováno v:
Nature Methods. Aug2009, Vol. 6 Issue 8, p593-595. 3p. 1 Chart, 2 Graphs.
Autor:
Aaron M. Leconte, Maha P. Patel, Mirna Jarosz, Lauryn E. Sass, J. William Efcavitch, Peter McInerney, Floyd E. Romesberg, Li Kung, Philip R. Buzby, Jayson Bowers
Publikováno v:
Angewandte Chemie (International ed. in English). 49(34)
We present the application of an activity-based phage display method to identify DNA polymerases tailored for next generation sequencing applications. Using this approach, we identify a mutant of Taq DNA polymerase that incorporates the fluorophore-l
Autor:
Jeffrey G. Reifenberger, Adam R. Platt, Jayson Bowers, Lauryn E. Sass, Mirna Jarosz, Patrice M. Milos, Dan Jones, Fatih Ozsolak, John F. Thompson, Peter McInerney
Publikováno v:
Nature. 461(7265)
Our understanding of human biology and disease is ultimately dependent on a complete understanding of the genome and its functions. The recent application of microarray and sequencing technologies to transcriptomics has changed the simplistic view of
Autor:
Philip R. Buzby, Suhaib Siddiqi, Peter McInerney, Kathleen E. Steinmann, Edyta Krzymanska-Olejnik, Jayson Bowers, John F. Thompson, Doron Lipson, Subramanian Marappan, J. William Efcavitch, Judith Mitchell, Marie Causey, Mirna Jarosz, Atanu Roy, Adam R. Platt, Eric Beer, Geoffrey M Lowman, Li Kung
Publikováno v:
Nature methods
Nucleotide analogs modified with a free 3′ hydroxyl, maintaining the interactions at the polymerase active site, and a cleavable linker, attaching a fluorescent dye and an inhibitor, are efficient at reading homopolymer runs in a single-molecule se
Autor:
Philip R. Buzby, Dan Lapen, Mirna Jarosz, Edward C. Thayer, Ido Braslavsky, Jayson Bowers, Keith A. Moulton, J. William Efcavitch, Howard Weiss, Marie Causey, Jaime Gill, Zheng Xie, Hazen P. Babcock, Stephen R. Quake, Rebecca Ward, John Healy, Eric Beer, Jennifer Colonell, Kathleen E. Steinmann, Eldar Giladi, Anastasia Tyurina, James Joseph Dimeo, Timothy D. Harris
Publikováno v:
Science (New York, N.Y.). 320(5872)
The full promise of human genomics will be realized only when the genomes of thousands of individuals can be sequenced for comparative analysis. A reference sequence enables the use of short read length. We report an amplification-free method for det