Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jayron J. Habibe"'
Autor:
Jayron J. Habibe, Ulrika Boulund, Maria P. Clemente-Olivo, Carlie J. M. de Vries, Etto C. Eringa, Max Nieuwdorp, Bart Ferwerda, Koos Zwinderman, Bert-Jan H. van den Born, Henrike Galenkamp, Daniel H. van Raalte
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4332 (2023)
Type 2 diabetes mellitus (T2D) is a prevalent disease often accompanied by the occurrence of dyslipidemia. Four and a half LIM domains 2 (FHL2) is a scaffolding protein, whose involvement in metabolic disease has recently been demonstrated. The assoc
Externí odkaz:
https://doaj.org/article/0f4a37c545a2467dbc45b02802214713
Publikováno v:
Cells, Vol 10, Iss 10, p 2611 (2021)
Susceptibility to complex pathological conditions such as obesity, type 2 diabetes and cardiovascular disease is highly variable among individuals and arises from specific changes in gene expression in combination with external factors. The regulatio
Externí odkaz:
https://doaj.org/article/9cbbba4e6f494da7a8261404702b43b5
Autor:
Jayron J. Habibe, Maria P. Clemente-Olivo, Torsten P. M. Scheithauer, Elena Rampanelli, Hilde Herrema, Mariska Vos, Arnout Mieremet, Max Nieuwdorp, Daniel H. van Raalte, Etto C. Eringa, Carlie J. M. de Vries
Publikováno v:
Diabetologia, 65(10):s00125-022-05750-1, 1721-1733. Springer, Cham
Diabetologia, 65(10), 1721-1733. Springer Verlag
Habibe, J J, Clemente-Olivo, M P, Scheithauer, T P M, Rampanelli, E, Herrema, H, Vos, M, Mieremet, A, Nieuwdorp, M, van Raalte, D H, Eringa, E C & de Vries, C J M 2022, ' Glucose-mediated insulin secretion is improved in FHL2-deficient mice and elevated FHL2 expression in humans is associated with type 2 diabetes ', Diabetologia, vol. 65, no. 10, pp. 1721-1733 . https://doi.org/10.1007/s00125-022-05750-1
Diabetologia, 65(10), 1721-1733. Springer Verlag
Habibe, J J, Clemente-Olivo, M P, Scheithauer, T P M, Rampanelli, E, Herrema, H, Vos, M, Mieremet, A, Nieuwdorp, M, van Raalte, D H, Eringa, E C & de Vries, C J M 2022, ' Glucose-mediated insulin secretion is improved in FHL2-deficient mice and elevated FHL2 expression in humans is associated with type 2 diabetes ', Diabetologia, vol. 65, no. 10, pp. 1721-1733 . https://doi.org/10.1007/s00125-022-05750-1
Aims/hypothesis The general population is ageing, involving an enhanced incidence of chronic diseases such as type 2 diabetes. With ageing, DNA methylation of FHL2 increases, as well as expression of the four and a half LIM domains 2 (FHL2) protein i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad1a0b6b39ebcc4c030dcc7270ac9cd3
https://doi.org/10.1007/s00125-022-05750-1
https://doi.org/10.1007/s00125-022-05750-1
Autor:
Patrick C.N. Rensen, Carlie J.M. de Vries, Jayron J. Habibe, Sander Kooijman, Hilde Herrema, Mariska Vos, Maria P. Clemente-Olivo, Roelof Ottenhoff, Max Nieuwdorp, Noam Zelcer, Aldo Jongejan, Etto C. Eringa, Daniël H. van Raalte
Publikováno v:
Metabolism: clinical and experimental, 121:154815. W.B. Saunders Ltd
Clemente-Olivo, M P, Habibe, J J, Vos, M, Ottenhoff, R, Jongejan, A, Herrema, H, Zelcer, N, Kooijman, S, Rensen, P C N, van Raalte, D H, Nieuwdorp, M, Eringa, E C & de Vries, C J 2021, ' Four-and-a-half LIM domain protein 2 (FHL2) deficiency protects mice from diet-induced obesity and high FHL2 expression marks human obesity ', Metabolism: Clinical and Experimental, vol. 121, 154815, pp. 1-14 . https://doi.org/10.1016/j.metabol.2021.154815
Metabolism
Metabolism: Clinical and Experimental, 121:154815, 1-14. W.B. Saunders Ltd
Metabolism, 121. W B SAUNDERS CO-ELSEVIER INC
Clemente-Olivo, M P, Habibe, J J, Vos, M, Ottenhoff, R, Jongejan, A, Herrema, H, Zelcer, N, Kooijman, S, Rensen, P C N, van Raalte, D H, Nieuwdorp, M, Eringa, E C & de Vries, C J 2021, ' Four-and-a-half LIM domain protein 2 (FHL2) deficiency protects mice from diet-induced obesity and high FHL2 expression marks human obesity ', Metabolism: Clinical and Experimental, vol. 121, 154815, pp. 1-14 . https://doi.org/10.1016/j.metabol.2021.154815
Metabolism
Metabolism: Clinical and Experimental, 121:154815, 1-14. W.B. Saunders Ltd
Metabolism, 121. W B SAUNDERS CO-ELSEVIER INC
Objective: Four-and-a-Half-LIM-domain-protein 2 (FHL2) modulates multiple signal transduction pathways but has not been implicated in obesity or energy metabolism. In humans, methylation and expression of the FHL2 gene increases with age, and high FH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472b5024a415674376f634c543371301
https://doi.org/10.1016/j.metabol.2021.154815
https://doi.org/10.1016/j.metabol.2021.154815