Comparative proteomic analysis of human milk fat globules and paired membranes and mouse milk fat globules identifies core cellular systems contributing to mammary lipid trafficking and secretion

Autor: Jayne F. Martin Carli, Monika Dzieciatkowska, Teri L. Hernandez, Jenifer Monks, James L. McManaman

Publikováno v: Frontiers in Molecular Biosciences, Vol 10 (2023)

Introduction: Human milk delivers critical nutritional and immunological support to human infants. Milk fat globules (MFGs) and their associated membranes (MFGMs) contain the majority of milk lipids and many bioactive components that contribute to ne

Externí odkaz: https://doaj.org/article/d61c911580294b00a489330831721a4c

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

Autor: Tuomas O. Kilpeläinen, Jayne F. Martin Carli, Alicja A. Skowronski, Qi Sun, Jennifer Kriebel, Mary F Feitosa, Åsa K. Hedman, Alexander W. Drong, James E. Hayes, Jinghua Zhao, Tune H. Pers, Ursula Schick, Niels Grarup, Zoltán Kutalik, Stella Trompet, Massimo Mangino, Kati Kristiansson, Marian Beekman, Leo-Pekka Lyytikäinen, Joel Eriksson, Peter Henneman, Jari Lahti, Toshiko Tanaka, Jian’an Luan, Fabiola Del Greco M, Dorota Pasko, Frida Renström, Sara M. Willems, Anubha Mahajan, Lynda M. Rose, Xiuqing Guo, Yongmei Liu, Marcus E. Kleber, Louis Pérusse, Tom Gaunt, Tarunveer S. Ahluwalia, Yun Ju Sung, Yolande F. Ramos, Najaf Amin, Antoinette Amuzu, Inês Barroso, Claire Bellis, John Blangero, Brendan M. Buckley, Stefan Böhringer, Yii-Der I Chen, Anton J. N. de Craen, David R. Crosslin, Caroline E. Dale, Zari Dastani, Felix R. Day, Joris Deelen, Graciela E. Delgado, Ayse Demirkan, Francis M. Finucane, Ian Ford, Melissa E. Garcia, Christian Gieger, Stefan Gustafsson, Göran Hallmans, Susan E. Hankinson, Aki S Havulinna, Christian Herder, Dena Hernandez, Andrew A. Hicks, David J. Hunter, Thomas Illig, Erik Ingelsson, Andreea Ioan-Facsinay, John-Olov Jansson, Nancy S. Jenny, Marit E. Jørgensen, Torben Jørgensen, Magnus Karlsson, Wolfgang Koenig, Peter Kraft, Joanneke Kwekkeboom, Tiina Laatikainen, Karl-Heinz Ladwig, Charles A. LeDuc, Gordon Lowe, Yingchang Lu, Pedro Marques-Vidal, Christa Meisinger, Cristina Menni, Andrew P. Morris, Richard H. Myers, Satu Männistö, Mike A. Nalls, Lavinia Paternoster, Annette Peters, Aruna D. Pradhan, Tuomo Rankinen, Laura J. Rasmussen-Torvik, Wolfgang Rathmann, Treva K. Rice, J Brent Richards, Paul M. Ridker, Naveed Sattar, David B. Savage, Stefan Söderberg, Nicholas J. Timpson, Liesbeth Vandenput, Diana van Heemst, Hae-Won Uh, Marie-Claude Vohl, Mark Walker, Heinz-Erich Wichmann, Elisabeth Widén, Andrew R. Wood, Jie Yao, Tanja Zeller, Yiying Zhang, Ingrid Meulenbelt, Margreet Kloppenburg, Arne Astrup, Thorkild I. A. Sørensen, Mark A. Sarzynski, D. C. Rao, Pekka Jousilahti, Erkki Vartiainen, Albert Hofman, Fernando Rivadeneira, André G. Uitterlinden, Eero Kajantie, Clive Osmond, Aarno Palotie, Johan G. Eriksson, Markku Heliövaara, Paul B. Knekt, Seppo Koskinen, Antti Jula, Markus Perola, Risto K. Huupponen, Jorma S. Viikari, Mika Kähönen, Terho Lehtimäki, Olli T. Raitakari, Dan Mellström, Mattias Lorentzon, Juan P. Casas, Stefanie Bandinelli, Winfried März, Aaron Isaacs, Ko W. van Dijk, Cornelia M. van Duijn, Tamara B. Harris, Claude Bouchard, Matthew A. Allison, Daniel I. Chasman, Claes Ohlsson, Lars Lind, Robert A. Scott, Claudia Langenberg, Nicholas J. Wareham, Luigi Ferrucci, Timothy M. Frayling, Peter P. Pramstaller, Ingrid B. Borecki, Dawn M. Waterworth, Sven Bergmann, Gérard Waeber, Peter Vollenweider, Henrik Vestergaard, Torben Hansen, Oluf Pedersen, Frank B. Hu, P Eline Slagboom, Harald Grallert, Tim D. Spector, J.W. Jukema, Robert J. Klein, Erik E Schadt, Paul W. Franks, Cecilia M. Lindgren, Rudolph L. Leibel, Ruth J. F. Loos

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)

This meta-analysis of genome-wide association studies identifies four genetic loci associated with circulating leptin levels independent of adiposity. Examination in mouse adipose tissue explants provides functional support for the leptin-associated

Externí odkaz: https://doaj.org/article/d58d296ffd8e4ac5ad80fa53bbfc1121

Resolving Human Lactation Heterogeneity Using Single Milk-Derived Cells, a Resource at the Ready

Autor: Michael C. Rudolph, Jayne F. Martin Carli, G Devon Trahan

Publikováno v: J Mammary Gland Biol Neoplasia

Single cell RNA sequencing (scRNAseq) of human milk-derived cells (HMDCs) makes highly detailed analyses of the biology of human lactation possible. We explore this powerful application as an exciting tool to inspect the cellular composition of human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5c038025d750a9d0ee1a6e49651668
https://pubmed.ncbi.nlm.nih.gov/34097179

List of contributors

Autor: Michael Affolter, Talat Bashir Ahmed, Stephanie Atkinson, Meghan B. Azad, Lydia A. Bazzano, Robert L. Beverly, David C. Dallas, Hans Demmelmair, Laura Di Manno, Sharon M. Donovan, Tanis R. Fenton, Leónides Fernández, Catherine J. Field, Peter Fransquet, Christoph Fusch, Gerhard Fusch, Clara L. Garcia-Rodenas, Donna Geddes, Donna T. Geddes, Margaret A. Hilliard, Michelle R. Hoffmann, Delyse Hutchinson, Jacqueline C. Kent, Berthold Koletzko, Celia Kwan, Sylvia H. Ley, Jayne F. Martin Carli, Gemma McLeod, James L. McManaman, Jenifer Monks, Pranati L. Panuganti, Sharon L. Perrella, Juan M. Rodríguez, Lorena Ruiz, Baidya Nath P. Sah, David A. Sela, Hannah F. Shoctor, Samantha Teague, Sagar K. Thakkar, Xiaomeng You, Janos Zempleni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a697219d22bbfecb2b5ec689719176a
https://doi.org/10.1016/b978-0-12-815350-5.00018-8

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.