Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jayne, Hammersley"'
Autor:
Dominic M. Walsh, Matthew J. Gardener, Jayne Hammersley, Michael S. Perkinton, Alexandra J. Mably, Tomas Ondrejcak, Wei Hong, Michael J. Rowan, Grant T. Corbett, Graham Fraser, Andrew Billinton, Igor Klyubin
Publikováno v:
The Journal of Neuroscience. 38:10595-10606
Intracellular neurofibrillary tangles (NFTs) composed of tau protein are a neuropathological hallmark of several neurodegenerative diseases, the most common of which is Alzheimer's disease (AD). For some time NFTs were considered the primary cause of
Autor:
Timothy O, Cox, Erik C, Gunther, A Harrison, Brody, Marius T, Chiasseu, Austin, Stoner, Levi M, Smith, Laura T, Haas, Jayne, Hammersley, Gareth, Rees, Bhupinder, Dosanjh, Maria, Groves, Matthew, Gardener, Claire, Dobson, Tristan, Vaughan, Iain, Chessell, Andrew, Billinton, Stephen M, Strittmatter
Publikováno v:
Annals of Clinical and Translational Neurology
Objective Amyloid‐beta oligomers (Aßo) trigger the development of Alzheimer's disease (AD) pathophysiology. Cellular prion protein (PrPC) initiates synaptic damage as a high affinity receptor for Aßo. Here, we evaluated the preclinical therapeuti
Autor:
Matthew A. Sleeman, Jayne Hammersley, Rose Marwood, Vikki Knights, Cyril Privezentzev, Trevor Wilkinson, Catherine Huntington, Jonathan Seaman, Tristan J. Vaughan, David Rider, David C. Lowe, Donna K. Finch, Margareta Ek, Tove Sjögren, Peter Cariuk, Jonna K Hakulinen, Julie A. Douthwaite, Joyce Young, Sudharsan Sridharan
Publikováno v:
mAbs
'mAbs ', vol: 7, pages: 152-166 (2015)
'mAbs ', vol: 7, pages: 152-166 (2015)
Therapeutic monoclonal antibodies targeting G-protein-coupled receptors (GPCRs) are desirable for intervention in a wide range of disease processes. The discovery of such antibodies is challenging due to a lack of stability of many GPCRs as purified
Autor:
Sui Seng Tee, Silvio Aime, Kevin M. Brindle, Robin Hesketh, De-En Hu, Dmitry Soloviev, David Y. Lewis, P. Stephen Patrick, Sandra M. Fulton, Jayne Hammersley, Louiza Loizou, Scott K. Lyons, Tiago B. Rodrigues, Mikko I. Kettunen
The ability to track cells and their patterns of gene expression in living organisms can increase our understanding of tissue development and disease. Gene reporters for bioluminescence, fluorescence, radionuclide, and magnetic resonance imaging (MRI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbcbe4fa8e2cdd053453f56eb00aeda4
https://europepmc.org/articles/PMC3890795/
https://europepmc.org/articles/PMC3890795/