Zobrazeno 1 - 10
of 256
pro vyhledávání: '"Jayne, A Franklyn"'
Autor:
Christopher J. McCabe, Kristien Boelaert, Jayne A. Franklyn, John C. Watkinson, Wendy E. Leadbeater, Jeffrey A. Knauf, Margaret C. Eggo, Adrian Warfield, Erica Gentilin, Vicki E. Smith, Robert I. Seed, Neil Sharma, Jim C.W. Fong, Greg D. Lewy, Martin L. Read
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Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135cefef3a1dba892a6fbb1f007ac725
https://doi.org/10.1158/0008-5472.22391399.v1
https://doi.org/10.1158/0008-5472.22391399.v1
Autor:
Christopher J. McCabe, Kristien Boelaert, Jayne A. Franklyn, John C. Watkinson, Wendy E. Leadbeater, Jeffrey A. Knauf, Margaret C. Eggo, Adrian Warfield, Erica Gentilin, Vicki E. Smith, Robert I. Seed, Neil Sharma, Jim C.W. Fong, Greg D. Lewy, Martin L. Read
Pituitary tumor transforming gene (PTTG)-binding factor (PBF or PTTG1IP) is a little characterized proto-oncogene that has been implicated in the etiology of breast and thyroid tumors. In this study, we created a murine transgenic model to target PBF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42353d8d2975333dc5409ddcf1604ee9
https://doi.org/10.1158/0008-5472.c.6503249.v1
https://doi.org/10.1158/0008-5472.c.6503249.v1
Autor:
Marco Medici, Eleonora Porcu, Giorgio Pistis, Alexander Teumer, Suzanne J Brown, Richard A Jensen, Rajesh Rawal, Greet L Roef, Theo S Plantinga, Sita H Vermeulen, Jari Lahti, Matthew J Simmonds, Lise Lotte N Husemoen, Rachel M Freathy, Beverley M Shields, Diana Pietzner, Rebecca Nagy, Linda Broer, Layal Chaker, Tim I M Korevaar, Maria Grazia Plia, Cinzia Sala, Uwe Völker, J Brent Richards, Fred C Sweep, Christian Gieger, Tanguy Corre, Eero Kajantie, Betina Thuesen, Youri E Taes, W Edward Visser, Andrew T Hattersley, Jürgen Kratzsch, Alexander Hamilton, Wei Li, Georg Homuth, Monia Lobina, Stefano Mariotti, Nicole Soranzo, Massimiliano Cocca, Matthias Nauck, Christin Spielhagen, Alec Ross, Alice Arnold, Martijn van de Bunt, Sandya Liyanarachchi, Margit Heier, Hans Jörgen Grabe, Corrado Masciullo, Tessel E Galesloot, Ee M Lim, Eva Reischl, Peter J Leedman, Sandra Lai, Alessandro Delitala, Alexandra P Bremner, David I W Philips, John P Beilby, Antonella Mulas, Matteo Vocale, Goncalo Abecasis, Tom Forsen, Alan James, Elisabeth Widen, Jennie Hui, Holger Prokisch, Ernst E Rietzschel, Aarno Palotie, Peter Feddema, Stephen J Fletcher, Katharina Schramm, Jerome I Rotter, Alexander Kluttig, Dörte Radke, Michela Traglia, Gabriela L Surdulescu, Huiling He, Jayne A Franklyn, Daniel Tiller, Bijay Vaidya, Tim de Meyer, Torben Jørgensen, Johan G Eriksson, Peter C O'Leary, Eric Wichmann, Ad R Hermus, Bruce M Psaty, Till Ittermann, Albert Hofman, Emanuele Bosi, David Schlessinger, Henri Wallaschofski, Nicola Pirastu, Yurii S Aulchenko, Albert de la Chapelle, Romana T Netea-Maier, Stephen C L Gough, Henriette Meyer Zu Schwabedissen, Timothy M Frayling, Jean-Marc Kaufman, Allan Linneberg, Katri Räikkönen, Johannes W A Smit, Lambertus A Kiemeney, Fernando Rivadeneira, André G Uitterlinden, John P Walsh, Christa Meisinger, Martin den Heijer, Theo J Visser, Timothy D Spector, Scott G Wilson, Henry Völzke, Anne Cappola, Daniela Toniolo, Serena Sanna, Silvia Naitza, Robin P Peeters
Publikováno v:
PLoS Genetics, Vol 10, Iss 2, p e1004123 (2014)
Autoimmune thyroid diseases (AITD) are common, affecting 2-5% of the general population. Individuals with positive thyroid peroxidase antibodies (TPOAbs) have an increased risk of autoimmune hypothyroidism (Hashimoto's thyroiditis), as well as autoim
Externí odkaz:
https://doaj.org/article/6d824980694a4a48a3e40759b1015386
Autor:
Elisavet Vasilopoulou, Laurence S Loubière, Heike Heuer, Marija Trajkovic-Arsic, Veerle M Darras, Theo J Visser, Gendie E Lash, Guy S Whitley, Christopher J McCabe, Jayne A Franklyn, Mark D Kilby, Shiao Y Chan
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65402 (2013)
Monocarboxylate transporter 8 (MCT8) is a well-established thyroid hormone (TH) transporter. In humans, MCT8 mutations result in changes in circulating TH concentrations and X-linked severe global neurodevelopmental delay. MCT8 is expressed in the hu
Externí odkaz:
https://doaj.org/article/acb0131e384246868b4b0c60476ad8d3
Autor:
Rafał Płoski, Oliver J Brand, Beata Jurecka-Lubieniecka, Maria Franaszczyk, Dorota Kula, Paweł Krajewski, Muhammad A Karamat, Matthew J Simmonds, Jayne A Franklyn, Stephen C L Gough, Barbara Jarząb, Tomasz Bednarczuk
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15512 (2010)
The thyroid stimulating hormone receptor (TSHR) gene is an established susceptibility locus for Graves' disease (GD), with recent studies refining association to two single nucleotide polymorphisms (SNPs), rs179247 and rs12101255, within TSHR intron
Externí odkaz:
https://doaj.org/article/30c432246e954350b2912d8eb92a24b5
Autor:
Corneliu A. Bodea, Benjamin M. Neale, Stephan Ripke, Mark J. Daly, Bernie Devlin, Kathryn Roeder, Murray Barclay, Laurent Peyrin-Biroulet, Mathias Chamaillard, Jean-Frederick Colombel, Mario Cottone, Anthony Croft, Renata D’Incà, Jonas Halfvarson, Katherine Hanigan, Paul Henderson, Jean-Pierre Hugot, Amir Karban, Nicholas A. Kennedy, Mohammed Azam Khan, Marc Lémann, Arie Levine, Dunecan Massey, Monica Milla, Grant W. Montgomery, Sok Meng Evelyn Ng, Ioannis Oikonomou, Harald Peeters, Deborah D. Proctor, Jean-Francois Rahier, Rebecca Roberts, Paul Rutgeerts, Frank Seibold, Laura Stronati, Kirstin M. Taylor, Leif Törkvist, Kullak Ublick, Johan Van Limbergen, Andre Van Gossum, Morten H. Vatn, Hu Zhang, Wei Zhang, Jane M. Andrews, Peter A. Bampton, Timothy H. Florin, Richard Gearry, Krupa Krishnaprasad, Ian C. Lawrance, Gillian Mahy, Graham Radford-Smith, Rebecca L. Roberts, Lisa A. Simms, Leila Amininijad, Isabelle Cleynen, Olivier Dewit, Denis Franchimont, Michel Georges, Debby Laukens, Emilie Theatre, André Van Gossum, Severine Vermeire, Guy Aumais, Leonard Baidoo, Arthur M. Barrie, Karen Beck, Edmond-Jean Bernard, David G. Binion, Alain Bitton, Steve R. Brant, Judy H. Cho, Albert Cohen, Kenneth Croitoru, Lisa W. Datta, Colette Deslandres, Richard H. Duerr, Debra Dutridge, John Ferguson, Joann Fultz, Philippe Goyette, Gordon R. Greenberg, Talin Haritunians, Gilles Jobin, Seymour Katz, Raymond G. Lahaie, Dermot P. McGovern, Linda Nelson, Sok Meng Ng, Kaida Ning, Pierre Paré, Miguel D. Regueiro, John D. Rioux, Elizabeth Ruggiero, L. Philip Schumm, Marc Schwartz, Regan Scott, Yashoda Sharma, Mark S. Silverberg, Denise Spears, A. Hillary Steinhart, Joanne M. Stempak, Jason M. Swoger, Constantina Tsagarelis, Clarence Zhang, Hongyu Zhao, Jan Aerts, Tariq Ahmad, Hazel Arbury, Anthony Attwood, Adam Auton, Stephen G. Ball, Anthony J. Balmforth, Chris Barnes, Jeffrey C. Barrett, Inês Barroso, Anne Barton, Amanda J. Bennett, Sanjeev Bhaskar, Katarzyna Blaszczyk, John Bowes, Oliver J. Brand, Peter S. Braund, Francesca Bredin, Gerome Breen, Morris J. Brown, Ian N. Bruce, Jaswinder Bull, Oliver S. Burren, John Burton, Jake Byrnes, Sian Caesar, Niall Cardin, Chris M. Clee, Alison J. Coffey, John M.C. Connell, Donald F. Conrad, Jason D. Cooper, Anna F. Dominiczak, Kate Downes, Hazel E. Drummond, Darshna Dudakia, Andrew Dunham, Bernadette Ebbs, Diana Eccles, Sarah Edkins, Cathryn Edwards, Anna Elliot, Paul Emery, David M. Evans, Gareth Evans, Steve Eyre, Anne Farmer, Nicol Ferrier, Edward Flynn, Alistair Forbes, Liz Forty, Jayne A. Franklyn, Timothy M. Frayling, Rachel M. Freathy, Eleni Giannoulatou, Polly Gibbs, Paul Gilbert, Katherine Gordon-Smith, Emma Gray, Elaine Green, Chris J. Groves, Detelina Grozeva, Rhian Gwilliam, Anita Hall, Naomi Hammond, Matt Hardy, Pile Harrison, Neelam Hassanali, Husam Hebaishi, Sarah Hines, Anne Hinks, Graham A. Hitman, Lynne Hocking, Chris Holmes, Eleanor Howard, Philip Howard, Joanna M.M. Howson, Debbie Hughes, Sarah Hunt, John D. Isaacs, Mahim Jain, Derek P. Jewell, Toby Johnson, Jennifer D. Jolley, Ian R. Jones, Lisa A. Jones, George Kirov, Cordelia F. Langford, Hana Lango-Allen, G. Mark Lathrop, James Lee, Kate L. Lee, Charlie Lees, Kevin Lewis, Cecilia M. Lindgren, Meeta Maisuria-Armer, Julian Maller, John Mansfield, Jonathan L. Marchini, Paul Martin, Dunecan C.O. Massey, Wendy L. McArdle, Peter McGuffin, Kirsten E. McLay, Gil McVean, Alex Mentzer, Michael L. Mimmack, Ann E. Morgan, Andrew P. Morris, Craig Mowat, Patricia B. Munroe, Simon Myers, William Newman, Elaine R. Nimmo, Michael C. O’Donovan, Abiodun Onipinla, Nigel R. Ovington, Michael J. Owen, Kimmo Palin, Aarno Palotie, Kirstie Parnell, Richard Pearson, David Pernet, John R.B. Perry, Anne Phillips, Vincent Plagnol, Natalie J. Prescott, Inga Prokopenko, Michael A. Quail, Suzanne Rafelt, Nigel W. Rayner, David M. Reid, Anthony Renwick, Susan M. Ring, Neil Robertson, Samuel Robson, Ellie Russell, David St Clair, Jennifer G. Sambrook, Jeremy D. Sanderson, Stephen J. Sawcer, Helen Schuilenburg, Carol E. Scott, Richard Scott, Sheila Seal, Sue Shaw-Hawkins, Beverley M. Shields, Matthew J. Simmonds, Debbie J. Smyth, Elilan Somaskantharajah, Katarina Spanova, Sophia Steer, Jonathan Stephens, Helen E. Stevens, Kathy Stirrups, Millicent A. Stone, David P. Strachan, Zhan Su, Deborah P.M. Symmons, John R. Thompson, Wendy Thomson, Martin D. Tobin, Mary E. Travers, Clare Turnbull, Damjan Vukcevic, Louise V. Wain, Mark Walker, Neil M. Walker, Chris Wallace, Margaret Warren-Perry, Nicholas A. Watkins, John Webster, Michael N. Weedon, Anthony G. Wilson, Matthew Woodburn, B. Paul Wordsworth, Chris Yau, Allan H. Young, Eleftheria Zeggini, Matthew A. Brown, Paul R. Burton, Mark J. Caulfield, Alastair Compston, Martin Farrall, Stephen C.L. Gough, Alistair S. Hall, Andrew T. Hattersley, Adrian V.S. Hill, Christopher G. Mathew, Marcus Pembrey, Jack Satsangi, Michael R. Stratton, Jane Worthington, Matthew E. Hurles, Audrey Duncanson, Willem H. Ouwehand, Miles Parkes, Nazneen Rahman, John A. Todd, Nilesh J. Samani, Dominic P. Kwiatkowski, Mark I. McCarthy, Nick Craddock, Panos Deloukas, Peter Donnelly, Jenefer M. Blackwell, Elvira Bramon, Juan P. Casas, Aiden Corvin, Janusz Jankowski, Hugh S. Markus, Colin N.A. Palmer, Robert Plomin, Anna Rautanen, Richard C. Trembath, Ananth C. Viswanathan, Nicholas W. Wood, Chris C.A. Spencer, Gavin Band, Céline Bellenguez, Colin Freeman, Garrett Hellenthal, Matti Pirinen, Amy Strange, Hannah Blackburn, Suzannah J. Bumpstead, Serge Dronov, Matthew Gillman, Alagurevathi Jayakumar, Owen T. McCann, Jennifer Liddle, Simon C. Potter, Radhi Ravindrarajah, Michelle Ricketts, Matthew Waller, Paul Weston, Sara Widaa, Pamela Whittaker
Publikováno v:
American journal of human genetics, Vol. 98, no. 5, p. 857-868 (2016)
A. Palotie on työryhmän Int IBD Genetics Consortium jäsen. One goal of human genetics is to understand the genetic basis of disease, a challenge for diseases of complex inheritance because risk alleles are few relative to the vast set of benign va
Autor:
Jayne A. Franklyn, W. T. Longstreth, Jacobijn Gussekloo, Tinh-Hai Collet, Misa Imaizumi, Robert Luben, Christine Baumgartner, Bruce M. Psaty, John P. Walsh, Kay-Tee Khaw, Anne B. Newman, Layal Chaker, Luigi Ferrucci, J. Wouter Jukema, Rui M. B. Maciel, Christoph Wanner, Marcus Dörr, Christiane Drechsler, Giorgio Iervasi, Alexandra Bremner, Graziano Ceresini, Manuel R. Blum, Ian Ford, Salman Razvi, Nicolas Rodondi, Wendy P. J. den Elzen, Stephan J. L. Bakker, M. Arfan Ikram, Rudi G. J. Westendorp, David J. Stott, Robin P. Peeters, Henry Völzke, José Augusto Sgarbi, Douglas C. Bauer, Anne R. Cappola, Oscar H. Franco, Marileen L.P. Portegies, Albert Hofman, Abbas Dehghan, Robin P. F. Dullaart, Marco Medici
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism
Journal of Clinical Endocrinology and Metabolism, 101(11), 4270-4282. Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 101(11), 4270-4282. ENDOCRINE SOC
Journal of Clinical Endocrinology and Metabolism, 101(11), 4270-4282
The Journal of clinical endocrinology and metabolism, vol. 101, no. 11, pp. 4270-4282
Journal of Clinical Endocrinology and Metabolism, 101(11), 4270-4282. Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 101(11), 4270-4282. ENDOCRINE SOC
Journal of Clinical Endocrinology and Metabolism, 101(11), 4270-4282
The Journal of clinical endocrinology and metabolism, vol. 101, no. 11, pp. 4270-4282
Context: The currently applied reference ranges for thyroid function are under debate. Despite evidence that thyroid function within the reference range is related with several cardiovascular disorders, its association with the risk of stroke has not
Autor:
Anne R. Cappola, Jacobijn Gussekloo, Oscar H. Franco, David J. Stott, Douglas C. Bauer, Robin P. Peeters, Henry Völzke, Manuel R. Blum, Giorgio Iervasi, Alexandra Bremner, Graziano Ceresini, Christiane Drechsler, José Augusto Sgarbi, Stephan J. L. Bakker, Wendy P. J. den Elzen, Abbas Dehghan, Marileen L.P. Portegies, Marco Medici, Layal Chaker, Jayne A. Franklyn, Rui M. B. Maciel, M. Arfan Ikram, Robin P. F. Dullaart, Salman Razvi, Nicolas Rodondi, Anne B. Newman, Kay-Tee Khaw, Ian Ford, J. Wouter Jukema, Misa Imaizumi, Robert Luben, Tinh-Hai Collet, John P. Walsh, Christine Baumgartner, Rudi G. J. Westendorp, Christoph Wanner, Luigi Ferrucci, Albert Hofman
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism
Journal of Clinical Endocrinology and Metabolism, 100(6), 2181-2191
Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, 100(6), 2181-2191. Endocrine Society
Journal of Clinical Endocrinology and Metabolism, vol. 100, no. 6, pp. 2181-2191
Journal of Clinical Endocrinology and Metabolism, 100(6), 2181-2191
Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, 100(6), 2181-2191. Endocrine Society
Journal of Clinical Endocrinology and Metabolism, vol. 100, no. 6, pp. 2181-2191
Objective: The objective was to determine the risk of stroke associated with subclinical hypothyroidism. Data Sources and Study Selection: Published prospective cohort studies were identified through a systematic search through November 2013 without
Autor:
Laurence Loubiere, Shiao-Yng Chan, Elisavet Vasilopoulou, Christopher McCabe, Gendie E. Lash, Mark D. Kilby, O. Ohizua, Jayne A. Franklyn
Publikováno v:
Human Reproduction (Oxford, England)
STUDY QUESTION: Does triiodothyronine (T3) regulate the secretion of angiogenic growth factors and cytokines by human decidual cells isolated from early pregnancy? SUMMARY ANSWER: T3 modulates the secretion of specific angiogenic growth factors and c
Autor:
Vicki Smith, Gregory Lewy, Perkin Kwan, Neil Sharma, Martin L. Read, Vikki L. Poole, Kristien Boelaert, Jim Fong, Gavin Ryan, Adrian Warfield, Jayne A. Franklyn, Andrea Bacon, Robert Seed, Sarah Stewart, Christopher McCabe
Publikováno v:
Endocrinology. 154:4408-4422
Human pituitary tumor transforming gene (hPTTG) is a multifunctional proto-oncogene implicated in the initiation and progression of several tumors. Phosphorylation of hPTTG is mediated by cyclin-dependent kinase 2 (CDC2), whereas cellular expression