Výsledky vyhledávání - "Jaymie L. Estrella"

An autophagy-inducing and TLR-2 activating BCG vaccine induces a robust protection against tuberculosis in mice

Autor: Jin Wang, Subramanian Dhandayuthapani, Dekai Zhang, Chandrashekhar Pasare, Kishore Das, Chinnaswamy Jagannath, Jianjun Sun, Arshad Khan, Robert L. Hunter, Jaymie L. Estrella, Emily Soudani, Sankaralingam Saikolappan, Pearl Bakhru, Christopher R. Singh, N. Tony Eissa, Yue Ma

Publikováno v: npj Vaccines, Vol 4, Iss 1, Pp 1-19 (2019)
NPJ Vaccines

Mycobacterium bovis BCG is widely used as a vaccine against tuberculosis due to M. tuberculosis (Mtb), which kills millions of people each year. BCG variably protects children, but not adults against tuberculosis. BCG evades phagosome maturation, aut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5fd43a56e2e43f9e3c366b2d4ef373
http://link.springer.com/article/10.1038/s41541-019-0122-8

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Effect of fetal hypoxia on heart susceptibility to ischemia and reperfusion injury in the adult rat

Autor: Charles A. Ducsay, Yuhui Xiao, Jaymie L. Estrella, Lubo Zhang, Raymond D. Gilbert, Guohu Li

Publikováno v: Journal of the Society for Gynecologic Investigation. 10:265-274

Epidemiologic studies showed an association between adverse intrauterine environment and ischemic heart disease in the adult. We tested the hypothesis that prenatal hypoxia increased the susceptibility of adult heart to ischemia-reperfusion (I-R) inj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2846c1df80a0f244dd0b671c3a9585
https://doi.org/10.1016/s1071-5576(03)00074-1

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Inhibitory effect of glucocorticoid on coronary artery endothelial function

Autor: Shumei Yang, Jaymie L. Estrella, Christi A. Bonar, Kestrel Rogers

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 283:H1922-H1928

Acute and chronic stresses are implicated in cardiovascular diseases including coronary artery disease. The present study was designed to examine the direct effects of the stress hormone cortisol on nitric oxide (NO) release and endothelial NO syntha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a8738cb6db9627d546a287c64c5062
https://doi.org/10.1152/ajpheart.00364.2002

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The fbpA/sapM double knock out strain of Mycobacterium tuberculosis is highly attenuated and immunogenic in macrophages

Autor: Jaymie L. Estrella, Smitha J. Sasindran, Sankaralingam Saikolappan, Arshad Khan, Lisa Y. Armitige, Subramanian Dhandayuthapani, Chinnaswamy Jagannath

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e36198 (2012)
PLoS ONE

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is the leading cause of death due to bacterial infections in mankind, and BCG, an attenuated strain of Mycobacterium bovis, is an approved vaccine. BCG sequesters in immature phagosomes o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe197c3990f23e7a029b1c49f6ab300
http://europepmc.org/articles/PMC3344844?pdf=render

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A Novel in vitro Human Macrophage Model to Study the Persistence of Mycobacterium tuberculosis Using Vitamin D3 and Retinoic Acid Activated THP-1 Macrophages

Autor: Xing Gong, Chinnaswamy Jagannath, Dorothy E. Lewis, Malini Rajagopalan, Robert L. Hunter, N. Tony Eissa, Jaymie L. Estrella, Celestine Kan-Sutton

Publikováno v: Frontiers in Microbiology

Mycobacterium tuberculosis (Mtb) replicates within the human macrophages and we investigated the activating effects of retinoic acid (RA) and vitamin D(3) (VD) on macrophages in relation to the viability of intracellular Mtb. A combination of these v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eedc0499f06af76ee7391914470d3509
http://europepmc.org/articles/PMC3128978

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