Výsledky vyhledávání - "Jayme B Stokes"

Akademický článek

Clinical, molecular and genetic validation of a murine orthotopic xenograft model of pancreatic adenocarcinoma using fresh human specimens.

Autor: Dustin M Walters, Jayme B Stokes, Sara J Adair, Edward B Stelow, Cheryl A Borgman, Bryce T Lowrey, Wenjun Xin, Edik M Blais, Jae K Lee, Jason A Papin, J Thomas Parsons, Todd W Bauer

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e77065 (2013)

BACKGROUND:Relevant preclinical models that recapitulate the key features of human pancreatic ductal adenocarcinoma (PDAC) are needed in order to provide biologically tractable models to probe disease progression and therapeutic responses and ultimat

Externí odkaz: https://doaj.org/article/366a8db7440643c59e739a86aa547bd9

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Data from Inhibition of Focal Adhesion Kinase by PF-562,271 Inhibits the Growth and Metastasis of Pancreatic Cancer Concomitant with Altering the Tumor Microenvironment

Autor: Todd W. Bauer, J. Thomas Parsons, Edward B. Stelow, Rosa F. Hwang, Amy H. Bouton, Keena S. Thomas, Bryce Lowrey, E. Dan Hershey, Robert W. Tilghman, Dustin M. Walters, Jill K. Slack-Davis, Sara J. Adair, Jayme B. Stokes

Current therapies for pancreatic ductal adenocarcinoma (PDA) target individual tumor cells. Focal adhesion kinase (FAK) is activated in PDA, and levels are inversely associated with survival. We investigated the effects of PF-562,271 (a small-molecul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::56c825e49051cd5c217e55c723b3c0db
https://doi.org/10.1158/1535-7163.c.6535327

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supplementary Figure Legends 1-2 from Inhibition of Focal Adhesion Kinase by PF-562,271 Inhibits the Growth and Metastasis of Pancreatic Cancer Concomitant with Altering the Tumor Microenvironment

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8443a22e8d282dd3647a33f2df7c77
https://doi.org/10.1158/1535-7163.22496581.v1

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Supplementary Figure 1 from Inhibition of Focal Adhesion Kinase by PF-562,271 Inhibits the Growth and Metastasis of Pancreatic Cancer Concomitant with Altering the Tumor Microenvironment

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55cab70b86759661744db3e096954f84
https://doi.org/10.1158/1535-7163.22496587

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Supplementary Figure 2 from Inhibition of Focal Adhesion Kinase by PF-562,271 Inhibits the Growth and Metastasis of Pancreatic Cancer Concomitant with Altering the Tumor Microenvironment

PDF file - 85K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c5e005b660060acc4add3e84c509ec
https://doi.org/10.1158/1535-7163.22496584

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Adrenalectomy for Adrenal-mediated Hypertension: National Surgical Quality Improvement Program Analysis of an Institutional Experience

Autor: Robert M. Carey, Florence E. Turrentine, Jayme B Stokes, Virginia B. Simpson, Philip W. Smith, Amber L. Shada, Shetal H. Padia, John B. Hanks

Publikováno v: The American Surgeon. 80:1152-1158

Adrenal-mediated hypertension (AMH) has been increasingly treated by laparoscopic adrenalectomy (LA). Metabolic derangements in patients with AMH could result in perioperative complications and mortality. Long-term operative and clinical outcomes aft

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c8cda205232a16bf3ef901d42494562e
https://doi.org/10.1177/000313481408001133

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Minimally invasive surgery fellowship does not adversely affect general surgery resident case volume: a decade of experience

Autor: Damien J. LaPar, Bruce D. Schirmer, Jayme B. Stokes, Peter T. Hallowell, Mohamed I. Dahman

Publikováno v: The American Journal of Surgery. 205:307-311

Background With the advent of clinical fellowships in general surgery, there has been a continual debate over the effect on general surgical resident training. Will a fellowship interfere with a chief resident's experience or case volume? The aim of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6554bc18e964bb47b57ba8d84874b7a1
https://doi.org/10.1016/j.amjsurg.2013.01.005

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Inhibition of the Growth of Patient-Derived Pancreatic Cancer Xenografts with the MEK Inhibitor Trametinib Is Augmented by Combined Treatment with the Epidermal Growth Factor Receptor/HER2 Inhibitor Lapatinib

Autor: Timothy E. Newhook, Tona M. Gilmer, Bryce T. Lowrey, Todd W. Bauer, Cheryl A. Borgman, Catharine R. Cowan, Maria E. Chopivsky, Sara J. Adair, Edward B. Stelow, Jayme B. Stokes, Dustin M. Walters, James M. Lindberg, John T. Parsons

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 2, Pp 143-155 (2013)

Mutations of the oncogene KRAS are important drivers of pancreatic cancer progression. Activation of epidermal growth factor receptor (EGFR) and human EGFR2 (HER2) is observed frequent in pancreatic adenocarcinomas. Because of co-activation of these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc5ab09b4a066d38d3af5d55b3cbc21
http://www.sciencedirect.com/science/article/pii/S1476558613800255

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Surgical Management of Hepatic Neuroendocrine Tumor Metastasis: Results from an International Multi-Institutional Analysis

Publikováno v: Annals of Surgical Oncology, Vol. 17, No 12 (2010) pp. 3129-3136

BACKGROUND: Management of neuroendocrine tumor liver metastasis (NELM) remains controversial, with some advocating an aggressive surgical approach while others have adopted a more conservative strategy. We sought to define the efficacy of the surgica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ffd5c8f5596d6308b932bf68534dbd
https://doi.org/10.1245/s10434-010-1154-5

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Laparoscopic Ventral Hernia Repair: Mesh Options and Outcomes

Autor: Charles M. Friel, Jayme B. Stokes

Publikováno v: Seminars in Colon and Rectal Surgery. 20:118-124

Laparoscopic ventral hernia repair (LVHR) offers a minimally invasive option for the repair of congenital or incisional abdominal wall hernias. A key component of LVHR is the placement of a prosthetic or biological mesh intraperitoneally to cover the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b9f6309d91b2456f213589582f869e73
https://doi.org/10.1053/j.scrs.2009.06.003

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