Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Jaylyn, Waddell"'
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S593- (2023)
Externí odkaz:
https://doaj.org/article/6377ebb2c55847659f7d6d09dd274760
Publikováno v:
Clinical and Translational Discovery, Vol 2, Iss 2, Pp n/a-n/a (2022)
Abstract This commentary describes chimeric antigen receptors (CAR)‐T cells' impact on solid tumors using novel preclinical models. In haematological malignancies, CAR‐T therapy has had a lot of success. Unfortunately, due to the complex tumour m
Externí odkaz:
https://doaj.org/article/70ba223c1da04b4999a24925111f34ef
Publikováno v:
Cells, Vol 12, Iss 9, p 1329 (2023)
The mitochondrion has a unique position among other cellular organelles due to its dynamic properties and symbiotic nature, which is reflected in an active exchange of metabolites and cofactors between the rest of the intracellular compartments. The
Externí odkaz:
https://doaj.org/article/b61f6a96c82f4f2b82a8531165e31347
Publikováno v:
Antioxidants, Vol 11, Iss 3, p 450 (2022)
Mitochondrial division inhibitor-1 (mdivi-1), a non-specific inhibitor of Drp1-dependent mitochondrial fission, is neuroprotective in numerous preclinical disease models. These include rodent models of Alzheimer’s disease and ischemic or traumatic
Externí odkaz:
https://doaj.org/article/f480accc42d24238a1b13004d5ad3753
Publikováno v:
Cells, Vol 10, Iss 11, p 3031 (2021)
Mitochondria are a unique intracellular organelle due to their evolutionary origin and multifunctional role in overall cellular physiology and pathophysiology. To meet the specific spatial metabolic demands within the cell, mitochondria are actively
Externí odkaz:
https://doaj.org/article/3bf7250e26d9477ca2981d5b5f5f88f2
Publikováno v:
Cells, Vol 10, Iss 9, p 2348 (2021)
Acetylation is a post-translational modification that regulates the activity of enzymes fundamentally involved in cellular and mitochondrial bioenergetic metabolism. NAD+ dependent deacetylase sirtuin 3 (SIRT3) is localized to mitochondria where it p
Externí odkaz:
https://doaj.org/article/bc04f0146fdb4484a95483b0c4ba56a2
Publikováno v:
Pediatric Research. 92:1325-1331
Hypoxic-ischemic encephalopathy (HIE) is a devastating disease with lifelong disabilities. Hypothermia is currently the only treatment. At term, the neonatal cerebellum may be particularly vulnerable to the effects of HIE. At this time, many developm
Publikováno v:
Pediatric Research.
Autor:
Tayo Adeyemo, Ayodele Jaiyesimi, Jill G. Bumgardner, Charity Lohr, Aditi Banerjee, Mary C. McKenna, Jaylyn Waddell
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 13983
Choline is an essential nutrient with many roles in brain development and function. Supplementation of choline in early development can have long-lasting benefits. Our experiments aimed to determine the efficacy of choline supplementation in a postna