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Thyroid hormone (T3) has been suggested to play a role in herpes simplex virus 1 (HSV-1) replication. It was previously reported that HSV-1 replication was suppressed by T3 in mouse neuroblastoma cells overexpressing thyroid hormone receptor β1 (TR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8e62b34f4afb235c4dca02fa2f9326
https://europepmc.org/articles/PMC4972698/
https://europepmc.org/articles/PMC4972698/
Publikováno v:
Cell research
Various factors/pathways including hormonal regulation have been suggested to control herpes simplex virus type 1 (HSV-1) latency and reactivation. Our computer analysis identified a DNA repeat containing thyroid hormone-responsive elements (TRE) in
Autor:
Rajeswara C Pinnoji, James M. Hill, Shao-Chung V Hsia, Gautam R Bedadala, Jayavardhana R Palem
Publikováno v:
Journal of Neurovirology. 16:13-24
Herpes simplex virus type 1 (HSV-1) undergoes acute infection in epithelial cells followed by establishment of latency in the neurons of trigeminal ganglia. The latent virus maintains a dormant state and can recurs spontaneously, suggesting transcrip
Autor:
Lorna Graham, Gautam R Bedadala, Harris E. McFerrin, James M. Hill, Shao-Chung Hsia, Jayavardhana R Palem
Publikováno v:
Virology Journal
Virology Journal, Vol 8, Iss 1, p 262 (2011)
Virology Journal, Vol 8, Iss 1, p 262 (2011)
Background Herpes simplex virus type-1 (HSV-1) infections can cause a number of diseases ranging from simple cold sores to dangerous keratitis and lethal encephalitis. The interaction between virus and host cells, critical for viral replication, is b
Publikováno v:
Planta medica. 77(1)
This study investigated the putative inhibitory effect of manzamine A on HSV-1 infection. Our results indicated that manzamine A effectively inhibited viral replication and infection in the cell line SIRC, a corneal cell line, at 1 µM. The existing