Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Jayati Sengupta"'
Autor:
Ritobrita Chakraborty, Sandip Dey, Pallabi Sil, Simanta Sarani Paul, Dipita Bhattacharyya, Anirban Bhunia, Jayati Sengupta, Krishnananda Chattopadhyay
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Chakraborty et al. present biophysical and structural insights into fibril-forming oligomers of alpha-synuclein stabilized by heme. They show that heme targets the His50 residue of the oligomers and locks the protein into a different conformation whi
Externí odkaz:
https://doaj.org/article/25742eb9b9d54e619cd7385d8ac904d4
Publikováno v:
ACS Omega, Vol 5, Iss 26, Pp 16128-16138 (2020)
Externí odkaz:
https://doaj.org/article/ba78fd4ff9fa49ab85686b8d6530ce61
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102044- (2021)
Summary: Cellular factories engage numerous highly complex “molecular machines” to perform pivotal biological functions. 3D structural visualization is an effective way to understand the functional mechanisms of these biomacromolecules. The “re
Externí odkaz:
https://doaj.org/article/be5a857363bb4703a85c242936b2b951
Publikováno v:
Bio-Protocol, Vol 10, Iss 15 (2020)
The serotonin 5-HT2A receptor (5-HT2AR) is a member of the GPCR family that is important for various neurological functions and whose dysregulation causes many mental health disorders. Structural investigations of 5-HT2AR require the production of fu
Externí odkaz:
https://doaj.org/article/03ce7610f20d41daa6e0fd8288d05e35
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153928 (2016)
In all life forms, decoding of messenger-RNA into polypeptide chain is accomplished by the ribosome. Several protein chaperones are known to bind at the exit of ribosomal tunnel to ensure proper folding of the nascent chain by inhibiting their premat
Externí odkaz:
https://doaj.org/article/b49022879fb64b5ea8f8418f37300bc0
Autor:
Manidip Shasmal, Jayati Sengupta
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31742 (2012)
Here we present analysis of a 3D cryo-EM map of the 70S ribosome from Mycobacterium smegmatis, a saprophytic cousin of the etiological agent of tuberculosis in humans, Mycobacterium tuberculosis. In comparison with the 3D structures of other prokaryo
Externí odkaz:
https://doaj.org/article/3de85032e6bb48d79138d94205be3c4e
Publikováno v:
Pediatric Nephrology. 38:945-955
Hypovitaminosis D has been reported to be common in chronic kidney disease (CKD) as well as in proteinuric disorders. We reviewed available evidence to assess clinically relevant effects of low vitamin D status and native vitamin D (NVD) therapy, in
Publikováno v:
Journal of Chemical Information and Modeling. 62:2522-2537
Autor:
Priya Baid, Jayati Sengupta
Pathogenic organisms encounter a broad range of stress conditions within host micro-environment and adopt variety of mechanisms to stall protein translation and protect translational machinery. Structural investigations of the ribosomes isolated from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac0f8a3cbf3b05f474b506e01a6513c9
https://doi.org/10.1101/2022.08.30.505801
https://doi.org/10.1101/2022.08.30.505801
Autor:
Jayati Sengupta, Amitabha Chattopadhyay, Parijat Sarkar, Aritra Bej, Sukanya Mozumder, Sujoy Mukherjee
Publikováno v:
Biophys Rev
Serotonin (5-hydroxytryptamine, 5-HT) is an intrinsically fluorescent neurotransmitter found in organisms spanning a wide evolutionary range. Serotonin exerts its diverse actions by binding to distinct cell membrane receptors which are classified int