Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jayati Mookerjee-Basu"'
Autor:
Jayati Mookerjee-Basu, David E. Muench, Lisa R. Trump-Durbin, H. Leighton Grimes, Kristopher L. Nazor, Kejian Zhang, Kenneth D. Greis, Kasiani C. Myers, Baobao Song, Carolyn Lutzko, Dietmar J. Kappes, Stuart Hay, Nathan Salomonis, Giang Pham, Kyle Ferchen, Rachel A. Serafin, Sing Sing Way, Pankaj Dwivedi, Jennifer C. Yu, Somchai Chutipongtanate, Andre Olsson, Kashish Chetal
Publikováno v:
Nature
Advances in genetics and sequencing have identified a plethora of disease-associated and disease-causing genetic alterations. To determine causality between genetics and disease, accurate models for molecular dissection are required; however, the rap
Autor:
Christina Go, Bryant Schultz, Yi Zhang, Bo Zhou, Robert Hooper, Jonathan Ladner, Dietmar J. Kappes, Elsie Samakai, Emmanuelle Nicolas, Jonathan Soboloff, M. Raza Zaidi, Warren G. Tourtellotte, Jayati Mookerjee-Basu, Shan He, Scott Gross, Yuanyuan Tian
Publikováno v:
EMBO Rep
While the zinc finger transcription factors EGR1, EGR2, and EGR3 are recognized as critical for T‐cell function, the role of EGR4 remains unstudied. Here, we show that EGR4 is rapidly upregulated upon TCR engagement, serving as a critical “brake
Autor:
Jayati Mookerjee-Basu, Suraj Peri, Emmanuelle Nicolas, Xiang Hua, Dietmar J. Kappes, Philip Czyzewicz, Lu Ge, Dai Zhongping, Juan I FuxmanBass, Qin Li, Albertha J.M. Walhout
Publikováno v:
Molecular Biology and Evolution. 36:39-53
ThPOK is a “master regulator” of T lymphocyte lineage choice, whose presence or absence is sufficient to dictate development to the CD4 or CD8 lineages, respectively. Induction of ThPOK is transcriptionally regulated, via a lineage-specific silen
Autor:
Shilpak Chatterjee, Ananda Mookerjee, Jayati Mookerjee Basu, Paramita Chakraborty, Avishek Ganguly, Arghya Adhikary, Debanjan Mukhopadhyay, Sudipto Ganguly, Rajdeep Banerjee, Mohammad Ashraf, Jaydip Biswas, Pradeep K Das, Gourisankar Sa, Mitali Chatterjee, Tanya Das, Soumitra Kumar Choudhuri
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7048 (2009)
BackgroundAt the early stages of carcinogenesis, the induction of tumor specific T cell mediated immunity seems to block the tumor growth and give protective anti-tumor immune response. However, tumor associated macrophages (TAMs) might play an immun
Externí odkaz:
https://doaj.org/article/c8018775291e48899d4fdd7cd87c113a
Autor:
Andrzej Fertala, Dietmar J. Kappes, Javad Parvizi, Jayati Mookerjee-Basu, Theresa A. Freeman, George J. Feldman
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 37(1)
DDH is a debilitating condition characterized by incomplete formation of the acetabulum leading to dislocation of the hip, suboptimal joint function and accelerated wear of the articular cartilage resulting in early onset crippling arthritis of the h
Publikováno v:
Nature Immunology. 18:10-12
Altered signaling via the T cell antigen receptor (TCR) promotes an adipose-tissue-like phenotype in invariant natural killer cells (iNKT cells) during thymic development and causes selective enrichment for iNKT cells in adipose tissues.
The molecular basis of differentiation of immature thymocyte precursors to alternate CD4 or CD8 lineage cells remains poorly understood, but appears to be controlled by differences in TCR signaling. Importantly, we have shown that the transcription f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::980fefbbd51d86592c967f8a57668172
https://doi.org/10.1201/9781315371689-5
https://doi.org/10.1201/9781315371689-5
Since the discovery that CD4 and CD8 T cells exhibit selective TCR specificity for MHC class II or I antigen-presenting molecules, respectively, the basis of CD4 and CD8 lineage commitment in the thymus has remained the focus of intense study. Studyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d674253325b1cfd5696974cbc4a080b0
https://doi.org/10.1016/b978-0-12-374279-7.04009-1
https://doi.org/10.1016/b978-0-12-374279-7.04009-1
Autor:
Sing Sing Way, Stuart Hay, Kyle Ferchen, Kenneth D. Greis, Kristopher Nazor, Jayati Mookerjee-Basu, Kashish Chetal, Nathan Salomonis, Kejian Zhang, H. Leighton Grimes, Kasiani C. Myers, Giang Pham, David E. Muench, Pankaj Dwivedi, Dietmar J. Kappes, Somchai Chutipongtanate
Publikováno v:
Blood. 132:18-18
Efforts to understand the genomic impact of human-disease-relevant genetic lesions and how they disrupt the normal sequence of cell-state transitions is hampered by a lack of defined hierarchical cellular states and corresponding networks of regulato
Autor:
Ksudiram Naskar, Krishna Pandey, Gayetri Tripathy, Manik Chandra Saha, Soumitra Kumar Choudhuri, Prabhat K. Sinha, Shyam Sundar, Jayati Mookerjee Basu, S. K. Singh, Ananda Mookerjee, Syamal Roy, Pradip Das, Sanjeev Bimal, Rajdeep Banerjee
Publikováno v:
Antimicrobial Agents and Chemotherapy. 52:1080-1093
The emergence of antimony (Sb) resistance has jeopardized the treatment of visceral leishmaniasis in various countries. Previous studies have considered the part played by leishmanial parasites in antimony resistance, but the involvement of host fact