Future needs for continuing innovation in hemophilia: improving outcomes for individuals of all severities, including women and those in resource-constrained regions

Autor: Jan Blatný, Jan Astermark, Cristina Catarino, Gerry Dolan, Karin Fijnvandraat, Cédric Hermans, Katharina Holstein, Víctor Jiménez-Yuste, Robert Klamroth, Michelle Lavin, Peter J. Lenting, Sébastien Lobet, Maria Elisa Mancuso, Jayashree Motwani, James S. O’Donnell, Christoph Königs

Publikováno v: Therapeutic Advances in Hematology, Vol 15 (2024)

Over recent decades, management of people with hemophilia (PwH) has been greatly improved by scientific advances that have resulted in a rich and varied therapeutic landscape. Nevertheless, treatment limitations continue to drive innovation, and emer

Externí odkaz: https://doaj.org/article/49b84b74635547b39a4cb8316ffbb30c

Detection of constitutional mismatch repair deficiency in children and adolescents with acute lymphoblastic leukemia

Autor: Richard, Gallon, Rachel, Phelps, Leigh, Betts, Christine, Hayes, Dino, Masic, Julie A E, Irving, Ciaron, McAnulty, Vaskar, Saha, Ajay, Vora, Katharina, Wimmer, Jayashree, Motwani, Christine, Macartney, John, Burn, Michael S, Jackson, Anthony V, Moorman, Mauro, Santibanez-Koref

Publikováno v: Leukemia & Lymphoma. 64:217-220

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbf34ac043a5225a51f9fe2b0539f4d
https://doi.org/10.1080/10428194.2022.2131412

Reduced Intensity Reinduction Followed By Blinatumomab Achieves Excellent MRD Clearance with Reduced Toxicity and Facilitates Timely Transplant in Children and Young People with Relapsed B-Precursor Acute Lymphoblastic Leukemia

Autor: Angus Hodder, Avijeet K Mishra, Katherine Clesham, Susan Baird, Kaljit Bhuller, Ismail Bisho, Denise Bonney, Anna Castleton, Michelle Cummins, Emmy Dickens, Lindsay George, Sara Ghorashian, Brenda Gibson, Chris Hasley, Nicholas Heaney, Rachael E Hough, Danielle Ingham, Galina Jigoulina, Katherine Lindsay, Donna Lancaster, Majid Madni, Andrea Malone, Bethany Mitchell, Anthony V. Moorman, John Moppett, Vanessa McLelland, Jayashree Motwani, Emma Nicholson, Caroline Osborne, Katharine Patrick, Lamia Samrin, Sanjay Tewari, Indu Rakesh Thakur, Sujith Samarasinghe, Ajay Vora, David O'Connor

Publikováno v: Blood. 140:3268-3270

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::64a97d220552d88872d3c949db3523e0
https://doi.org/10.1182/blood-2022-162565

Immune tolerance induction in severe haemophilia A: A UKHCDO inhibitor and paediatric working party consensus update

Autor: Jayanthi Alamelu, Tina T. Biss, Mary Mathias, Georgina W. Hall, Oliver Tunstall, Neha Bhatnagar, Elizabeth Chalmers, Charles R. M. Hay, Jeanette Payne, Daniel P. Hart, Ben Palmer, Michael Makris, Charles Percy, Kate Talks, Peter William Collins, Anne Riddell, Michael Richards, Ri Liesner, Jayashree Motwani

Publikováno v: Haemophilia. 27:932-937

INTRODUCTION In good risk patients (historic inhibitor peak

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21df19fb3684882c3a8bacb524383494
https://doi.org/10.1111/hae.14381

Safety and efficacy of rivaroxaban in pediatric cerebral venous thrombosis (EINSTEIN-Jr CVT)

Autor: Susan Baird, Fanny Bajolle, Sebastian Grunt, Olga Lvova, Anthonie W. A. Lensing, Mayte Sánchez van Kammen, William T. Smith, Paolo Simioni, Madhurima Majumder, Christoph Male, Jeanette Payne, Tina T. Biss, Michelle Morales Soto, Veerle Labarque, Elizabeth Chalmers, Joseph Palumbo, Jonathan M. Coutinho, Damien Bonnet, Amparo Santamaría, Riten Kumar, An Van Damme, Ida Martinelli, Kamar Godder, Sanjay J. Shah, Paul Monagle, Paola Saracco, Dagmar Kubitza, Philip Connor, Martin H. Prins, Rukhmi Bhat, Krisztián Kállay, Akos F. Pap, Scott D. Berkowitz, Kerry Hege, Jayashree Motwani, Helene L. Hooimeijer

Publikováno v: Blood advances, 4(24), 6250-6258. The American Society of Hematology
Blood Advances
r-FISABIO. Repositorio Institucional de Producción Científica
instname
Blood advances, 4(24), 6250-6258. American Society of Hematology
Blood Adv.
Blood Adv

Anticoagulant treatment of pediatric cerebral venous thrombosis has not been evaluated in randomized trials. We evaluated the safety and efficacy of rivaroxaban and standard anticoagulants in the predefined subgroup of children with cerebral venous t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be998519446ecd55ada264f5dbeff705
https://doi.org/10.1182/bloodadvances.2020003244