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of 12
pro vyhledávání: '"Jayashree, Kumar"'
Autor:
Jayashree Kumar, Lela Lackey, Justin M Waldern, Abhishek Dey, Anthony M Mustoe, Kevin M Weeks, David H Mathews, Alain Laederach
Publikováno v:
eLife, Vol 11 (2022)
Splicing is highly regulated and is modulated by numerous factors. Quantitative predictions for how a mutation will affect precursor mRNA (pre-mRNA) structure and downstream function are particularly challenging. Here, we use a novel chemical probing
Externí odkaz:
https://doaj.org/article/7e9b5b2f330645718e814d97ac9b25a0
Autor:
Philip J Grayeski, Chase A Weidmann, Jayashree Kumar, Lela Lackey, Anthony M Mustoe, Steven Busan, Alain Laederach, Kevin M Weeks
Publikováno v:
Nucleic Acids Research. 50:9689-9704
SERPINA1 mRNAs encode the protease inhibitor α-1-antitrypsin and are regulated through post-transcriptional mechanisms. α-1-antitrypsin deficiency leads to chronic obstructive pulmonary disease (COPD) and liver cirrhosis, and specific variants in t
Publikováno v:
Biology Open, Vol 5, Iss 11, Pp 1648-1661 (2016)
During development, cell proliferation and differentiation must be tightly coordinated to ensure proper tissue morphogenesis. Because steroid hormones are central regulators of developmental timing, understanding the links between steroid hormone sig
Externí odkaz:
https://doaj.org/article/2fdae41b4782404ba676a6eb53180787
Autor:
Jayashree, Kumar, Lela, Lackey, Justin M, Waldern, Abhishek, Dey, Anthony M, Mustoe, Kevin M, Weeks, David H, Mathews, Alain, Laederach
Publikováno v:
eLife. 11
Splicing is highly regulated and is modulated by numerous factors. Quantitative predictions for how a mutation will affect precursor mRNA (pre-mRNA) structure and downstream function are particularly challenging. Here, we use a novel chemical probing
Publikováno v:
Human genetics. 141(10)
Disease-associated variants (DAVs) are commonly considered either through a genomic lens that describes variant function at the DNA level, or at the protein function level if the variant is translated. Although the genomic and proteomic effects of va
Publikováno v:
Biology Open, Vol 5, Iss 11, Pp 1648-1661 (2016)
Biology Open
Biology Open
During development, cell proliferation and differentiation must be tightly coordinated to ensure proper tissue morphogenesis. Because steroid hormones are central regulators of developmental timing, understanding the links between steroid hormone sig
Autor:
Samuel C. Wolff, Hong Yi, Hui Xiao Chao, Rachel A. Haggerty, Gavin D. Grant, Katarzyna M. Kedziora, Jayashree Kumar, David Borland, Jeanette Gowen Cook, Jeremy E. Purvis
Summary The cell cycle is driven by precise temporal coordination among many molecular activities. To understand and explore this process, we developed the Cell Cycle Browser (CCB), an interactive web interface based on real-time reporter data collec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7d1916bdf314ab5555250c0497bea5
https://doi.org/10.1101/234039
https://doi.org/10.1101/234039
Saccharomyces cerevisiaeencodes two distinct Pif1-family helicases – Pif1 and Rrm3 – which have been reported to play distinct roles in numerous nuclear processes. Here, we systematically characterize the roles of Pif1 helicases in replisome prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cce3077165f1ae7ed4da8bda3d96d4
https://doi.org/10.1101/082008
https://doi.org/10.1101/082008