Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jayanthi Ganesan"'
Autor:
Eva Jüttner, Ulrike V. Gerlach, Andreas Beilhack, Alf Zerweck, Konrad Wilhelm, Neeraja Kambham, Tobias Müller, Francesco Di Virgilio, Jürgen Finke, Paul Fisch, Robert Zeiser, Christine D. Krempl, Marco Idzko, Christoph Dürr, Davide Ferrari, Patrizia Pellegatti, Melanie Grimm, Stephan Sorichter, Jayanthi Ganesan, Frank Gärtner
Publikováno v:
Nature Medicine. 16:1434-1438
Danger signals released upon cell damage can cause excessive immune-mediated tissue destruction such as that found in acute graft-versus-host disease (GVHD), allograft rejection and systemic inflammatory response syndrome. Given that ATP is found in
Autor:
Felix C. Weber, Philippp R. Esser, Markus M. Simon, Robert Zeiser, Thilo Jakob, Tobias Müller, Stefan F. Martin, Patrizia Pellegatti, Jayanthi Ganesan, Marko Idzko
Publikováno v:
The Journal of Experimental Medicine
Engagement of P2X7 on mouse dendritic cells, presumably by ATP released in response to contact allergen, is needed for IL-1β production and the sensitization phase of contact hypersensitivity.
Sensitization to contact allergens requires activat
Sensitization to contact allergens requires activat
Autor:
Marco Idzko, Natalie Stickel, Aubry Tardivel, Kristina Ludigs, Abdellatif Bouazzaoui, Michael Bscheider, Jayanthi Ganesan, Jürgen Finke, Anand Manoharan, Hendrik Poeck, Dragana Jankovic, Robert Zeiser, Marie Follo, Felix C. Weber, Dietmar Pfeifer, Leonard Müller, Katrin Kerl, Ernst Holler, Stefan F. Martin, Justus Duyster, Oliver Gorka, Greta Guarda, Julius C. Fischer, Emmanuel Contassot, Tobias Haas, Annette Schmitt-Gräff, Lars E. French, Jürgen Ruland, Christian Peschel
Publikováno v:
The Journal of Experimental Medicine
The Journal of experimental medicine
Journal of Experimental Medicine, vol. 210, no. 10, pp. 1899-1910
The Journal of experimental medicine
Journal of Experimental Medicine, vol. 210, no. 10, pp. 1899-1910
Conditioning therapies before transplantation induce the release of uric acid, which triggers the NLRP3 inflammasome and IL-1β production contributing to graft-versus-host disease.
The success of allogeneic hematopoietic cell transplantation is
The success of allogeneic hematopoietic cell transplantation is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869f80204c8936dbd69868a87a65f9bd
https://www.zora.uzh.ch/id/eprint/87699/
https://www.zora.uzh.ch/id/eprint/87699/
Autor:
Jerry W. Ritchey, Linda F. Thompson, Ulrike V. Gerlach, Marco Idzko, Marie Follo, Robert Zeiser, Ankur Rughani, Korcan Ayata, Hiroki Tsukamoto, Jayanthi Ganesan, Petya Chernogorova
Publikováno v:
Blood. 119(19)
Extracellular ATP and adenosine have immunoregulatory roles during inflammation. Elevated extracellular ATP is known to exacerbate GVHD, and the pharmacologic activation of the adenosine A2A receptor is protective. However, the role of endogenous ade
Autor:
Luis García-Fernández, Holger Weber, Jan E. Ehlert, Miguel Aracil Ávila, Sarah Umber, Oliver Siedentopf, Jayanthi Ganesan, Michael H.G. Kubbutat, Daniel Feger
Publikováno v:
Cancer Research. 74:2026-2026
Multiple myeloma (MM) is a severe leukemic disease of plasma B-cells in the bone marrow to which there is currently no cure. Stromal components such as mesenchymal stromal cells (MSC) or endothelial cells (EC) are suspected to play a central role in
Autor:
Petya Chernogorova, Hiroki Tsukamoto, Korcan Ayata, Ulrike V. Gerlach, Ankur Rughani, Jayanthi Ganesan, Marie Follo, Linda F. Thompson, Marco Idzko, Robert Zeiser
Publikováno v:
Blood. 118:312-312
Abstract 312 Acute graft-versus-host disease (GvHD) limits the success of allogeneic hematopoietic cell transplantation (allo-HCT). We have recently shown that extracellular adenosine triphosphate (ATP) enhances GvHD by activation of the purinergic r
Autor:
Konrad Wilhelm, Jayanthi Ganesan, Christoph Dürr, Jürgen Finke, Alf Zerweck, Ulrike V. Gerlach, Robert Zeiser, Marco Idzko, Tobias Müller
Publikováno v:
Blood. 114:1336-1336
Abstract 1336 Poster Board I-358 Conditioning prior allogeneic hematopoietic cell transplantation causes local tissue injury. Cellular molecules that are released upon cell stress, injury or cell death can act as potent danger associated molecular pa