Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Jayanta K Pal"'
Publikováno v:
Future Science OA, Vol 5, Iss 6 (2019)
The tumor microenvironment (TME) comprises a heterogeneous number and type of cellular and noncellular components that vary in the context of molecular, genomic and epigenomic levels. The genotypic diversity and plasticity within cancer cells are kno
Externí odkaz:
https://doaj.org/article/74b6671f623e4e2595bc4470cf015bb8
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156032 (2016)
Translation regulation in Leishmania parasites assumes significance particularly because they encounter myriad of stresses during their life cycle. The eukaryotic initiation factor 2α (eIF2α) kinases, the well-known regulators of translation initia
Externí odkaz:
https://doaj.org/article/a980233f5106465c9846f50a4b26beae
Autor:
Rushikesh Patel, Ajay Kumar, Kiran Bharat Lokhande, Mrudula Joshi, Kratika Khunteta, Jayanta K. pal, Prof. Nilesh Kumar Sharma
Background As per the Warburg effect, cancer cells are known to convert pyruvate into lactate. The accumulation of lactate is associated with metabolic and epigenetic reprogramming, which has newly been suggested to involve lactylation. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b90b95df0165a6d97bcf3ff1469e0de8
https://doi.org/10.26434/chemrxiv-2023-dp5kt-v2
https://doi.org/10.26434/chemrxiv-2023-dp5kt-v2
Autor:
Prakash Baligar, Jayanta K. Pal, Manoj Garg, Eiji Yuba, Gautam Sethi, Amit Awasthi, Vaishnavi U Warrier, Anuradha Kirtonia, Daizy Sadaria, Ravi Kant, Bhavika Gupta, Rajesh Kumar Gupta
Publikováno v:
Seminars in Cancer Biology. 80:87-106
Plant lectins, a natural source of glycans with a therapeutic potential may lead to the discovery of new targeted therapies. Glycans extracted from plant lectins are known to act as ligands for C-type lectin receptors (CLRs) that are primarily presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7431ff3d7ba4fcc4baf7a45fc4858eb6
https://doi.org/10.1016/j.semcancer.2020.02.005
https://doi.org/10.1016/j.semcancer.2020.02.005
Autor:
Nilesh Kumar Sharma, Ajay Kumar Raj, Kiran Bharat Lokhande, Tanay K Prasad, Rasika Nandangiri, Sumitra Choudhary, Jayanta K. Pal
Publikováno v:
Current Molecular Medicine. 23
Background: Dietary chemicals and their gut-metabolized products are explored for their anti-proliferative and pro-cell death effects. Dietary and metabolized chemicals are different from ruminants such as goats over humans. Methods: Loss of cell via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b271322e90a88ebc19ef167395272f83
https://doi.org/10.2174/1566524023666230113141032
https://doi.org/10.2174/1566524023666230113141032
Autor:
Anwesha Deep Dutta, Ajay Kumar, Kiran Bharat Lokhande, Manmohan Mitruka, K. Venkateswara Swamy, Jayanta K. Pal, Sachin C. Sarode, Nilesh Kumar Sharma
Publikováno v:
Current Chemical Biology. 15:301-309
Background: Nicotine-metabolized product nicotine imine is suggested to play a role in metabolic changes in oral cancer. There is a significant gap in the detection of oncometabolite nicotine imine in biological fluids and nails of oral cancer patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5d2e4612a05eabc19e4d1c5fdc2c8dc
https://doi.org/10.2174/2212796816666211223105911
https://doi.org/10.2174/2212796816666211223105911
Autor:
Hritik Chandore, Nilesh Kumar Sharma, Ajay Kumar Raj, Kiran Bharat Lokhande, K. Venkateswara Swamy, Jayanta K Pal
Publikováno v:
Protein & Peptide Letters. 28:1191-1202
BackgroundThe need of agonists and antagonists of β2 adrenoceptor (β2AR) is warranted in various human disease conditions including cancer, cardiovascular and other metabolic disorders. However, the sources of agonists of β2AR are diverse in natur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4300a267441ea9e53415da02d6a46dc8
https://doi.org/10.2174/0929866528666210816114901
https://doi.org/10.2174/0929866528666210816114901
Autor:
Nilesh Kumar Sharma, Jayanta K Pal
Publikováno v:
Current Molecular Medicine. 21:177-181
Tumor heterogeneity is influenced by various factors including genetic, epigenetic and axis of metabolic-epigenomic regulation. In recent years, metabolic-epigenomic reprogramming has been considered as one of the many tumor hallmarks and it appears
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8858a349161e6f05200d83e7dbe986e6
https://doi.org/10.2174/1566524020666200521075252
https://doi.org/10.2174/1566524020666200521075252
Publikováno v:
Current Protein & Peptide Science. 21:1085-1096
With the emergence of the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the whole world is suffering from atypical pneumonia, which resulted in more than 559,047 deaths worldwide. In this time of crisis and urgency, the only hop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557eb20df0a458fb7e8a13c661043527
https://doi.org/10.2174/1389203721666200918153717
https://doi.org/10.2174/1389203721666200918153717
Autor:
Rajesh Kumar Gupta, Ashutosh Singh, K. Venkateswara Swamy, Kiran Bharat Lokhande, Girish R. Apte, Ashish Shrivastava, Jayanta K. Pal
Publikováno v:
Journal of Biomolecular Structure & Dynamics
article-version (VoR) Version of Record
Journal of Biomolecular Structure and Dynamics
article-version (VoR) Version of Record
Journal of Biomolecular Structure and Dynamics
A recent surge in finding new candidate vaccines and potential antivirals to tackle atypical pneumonia triggered by the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) needs new and unexplored approaches in solving this global pand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7020e389dcb0a07ac2adf9e50b53c9d
http://europepmc.org/articles/PMC7745641
http://europepmc.org/articles/PMC7745641