Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jayant S. Kulkarni"'
Autor:
Rakesh S, Shinde, Pradip Pai, Dhungat, Jayant S, Kulkarni, Dilip P, Bhoge, Ramdas S, Joshi, Amey A, Bedekar
Publikováno v:
The Journal of the Association of Physicians of India. 69(4)
Dandy-Walker variant consists of vermian hypoplasia and cystic dilatation of the fourth ventricle, without enlargement of the posterior fossa is a distinctive entity believed to represent a mild subtype of Dandy-Walker complex. We report a case of 66
Publikováno v:
Journal of Neurochemistry. 71:1889-1897
Removal of nerve growth factor (NGF) from sympathetic neurons initiates a neuronal death program and apoptosis. We show that pituitary adenylyl cyclase-activating polypeptide (PACAP) prevents apoptosis in NGF-deprived sympathetic neurons. PACAP (100
Publikováno v:
Neuroscience Letters. 252:163-166
Our past work on nucleoside toxicity in sympathetic neurons has clearly revealed that adenosine and 2'-deoxyadenosine (dAdo) have different mechanisms of action in inducing apoptotic death. For example, adenosine is toxic to neurons only during early
Publikováno v:
Neuroscience Letters. 248:187-190
Our previous work has established that adenosine is toxic to chick embryonic sympathetic neurons and kills freshly plated neurons by a process of apoptosis. Although the exact mechanism remains unknown, we found that phosphorylation of adenosine was
Publikováno v:
Journal of Biological Chemistry. 270:17986-17992
Postmitotic sympathetic neurons are known to undergo a programmed cell death (apoptosis) when they are deprived of nerve growth factor (NGF) or treated with arabinofuranosyl nucleoside antimetabolites. Here we report the existence of a biochemical me
Publikováno v:
Neuroscience Letters. 229:138-140
Chronic activation of protein kinase C (PKC) has been implicated in regulation of Ca 2+ entry responsible for normal development of transmitter properties in cultured sympathetic neurons. The idea that PKC alters the expression of Ca 2+ channels was
Publikováno v:
Pharmacological research. 46(2)
We have studied the effects of chronic treatment with cromakalim (75 ug kg(-1) per day) and glibenclamide (20 mg kg(-1) per day) in alloxan-induced diabetic rats. Injection of alloxan (60 mg kg(-1)/i.v., single dose) produced a significant increase i
Publikováno v:
Cell and tissue research. 296(2)
Previous work has shown that nucleosides produce apoptosis in sympathetic ganglion (SG) cells in vitro. The present study examined the effects of nucleosides on the development of the chick embryo in vivo with special attention to the SG and the opti
Publikováno v:
Brain research. 788(1-2)
Recently, we have demonstrated that adenosine and 2′-deoxyadenosine are toxic to embryonic sympathetic neurons and proposed that purine and pyrimidine metabolism may play a critical role in the growth and development of sympathetic neurons. To exte
Autor:
Taruna D. Wakade, Kenneth C. Palmer, Arun R. Wakade, Jayant S. Kulkarni, Xi Guo, Dennis A. Przywara
Publikováno v:
Journal of neurochemistry. 67(6)
We show here that 2'-deoxyadenosine (2'-dAdo) but not adenosine was toxic to chromaffin cells of 3-4-week-old rat adrenal glands. More than 75% of the cells plated in culture gradually died over a 3-day period in the presence of 100 microM 2'-dAdo pl