Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jayant Avva"'
Autor:
Eswar Shankar, Michael C. Weis, Jayant Avva, Sanjeev Shukla, Meenakshi Shukla, Sree N. Sreenath, Sanjay Gupta
Publikováno v:
Cells, Vol 8, Iss 3, p 201 (2019)
Phosphatidylinositol 3′-OH kinase (PI3K)-Akt and transcription factor NF-κB are important molecules involved in the regulation of cell proliferation, apoptosis, and oncogenesis. Both PI3K-Akt and Nuclear Factor-kappaB (NF-κB) are involved in the
Externí odkaz:
https://doaj.org/article/3bf7f503c88e447a94daaf511b05829e
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97130 (2014)
Few of >150 published cell cycle modeling efforts use significant levels of data for tuning and validation. This reflects the difficultly to generate correlated quantitative data, and it points out a critical uncertainty in modeling efforts. To devel
Externí odkaz:
https://doaj.org/article/a81b912fe34b4838b43431951f82fe21
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e38275 (2012)
Cytometry of asynchronous proliferating cell populations produces data with an extractable time-based feature embedded in the frequency of clustered, correlated events. Here, we present a specific case of general methodology for calculating dynamic e
Externí odkaz:
https://doaj.org/article/8f5e1168eaa74f8688181fbf0d8354b9
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30870 (2012)
An imprecise quantitative sense for the oscillating levels of proteins and their modifications, interactions, and translocations as a function of the cell cycle is fundamentally important for a cartoon/narrative understanding for how the cell cycle w
Externí odkaz:
https://doaj.org/article/cec9bc4623664e4ba85bda871bc3588d
Autor:
Takhar Kasumov, Sergei Ilchenko, Rovshan G. Sadygov, Ahmad Borzou, Jayant Avva, Kwangwon Lee, Mahbubur Rahman
Publikováno v:
J Proteome Res
Metabolic labeling with heavy water followed by LC-MS is a high throughput approach to study proteostasis in vivo. Advances in mass spectrometry and sample processing have allowed consistent detection of thousands of proteins at multiple time points.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b6df6bf1ea10b001d601d6396c02d6
https://doi.org/10.1021/acs.jproteome.1c00698
https://doi.org/10.1021/acs.jproteome.1c00698
Autor:
James S. Malter, John D. Gordan, Lani F. Wu, Satwik Rajaram, Robert S. Warren, Jayant Avva, Chloe E. Atreya, Kathy Bonness, Steven J. Altschuler, Agnieszka K. Witkiewicz, Louise Heinrich
Publikováno v:
Nature methods, vol 14, iss 10
Rajaram, S; Heinrich, LE; Gordan, JD; Avva, J; Bonness, KM; Witkiewicz, AK; et al.(2017). Sampling strategies to capture single-cell heterogeneity. NATURE METHODS, 14(10), 967-+. doi: 10.1038/NMETH.4427. UCSF: Retrieved from: http://www.escholarship.org/uc/item/9857d75s
Nature methods
Rajaram, S; Heinrich, LE; Gordan, JD; Avva, J; Bonness, KM; Witkiewicz, AK; et al.(2017). Sampling strategies to capture single-cell heterogeneity. NATURE METHODS, 14(10), 967-+. doi: 10.1038/NMETH.4427. UCSF: Retrieved from: http://www.escholarship.org/uc/item/9857d75s
Nature methods
Advances in single-cell technologies have highlighted the prevalence and biological significance of cellular heterogeneity. A critical question is how to design experiments that faithfully capture the true range of heterogeneity from samples of cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706787d0212cfc74f77dfd37e425282a
https://escholarship.org/uc/item/9857d75s
https://escholarship.org/uc/item/9857d75s
Autor:
Olaf Wolkenhauer, Thomas Millat, Kwang-Hyun Cho, Radina P. Soebiyanto, Sree N. Sreenath, Jayant Avva
Publikováno v:
Biosystems. 92:270-281
Bistable systems play an important role in the functioning of living cells. Depending on the strength of the necessary positive feedback one can distinguish between (irreversible) "one-way switch" or (reversible) "toggle-switch" type behavior. Beside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f60ede2fa5791f98ae71bd1909639121
https://doi.org/10.1016/j.biosystems.2008.03.007
https://doi.org/10.1016/j.biosystems.2008.03.007
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 5, p e97130 (2014)
PLoS ONE, Vol 9, Iss 5, p e97130 (2014)
Few of >150 published cell cycle modeling efforts use significant levels of data for tuning and validation. This reflects the difficultly to generate correlated quantitative data, and it points out a critical uncertainty in modeling efforts. To devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca2236f4b7a98c3c423399f20bb7335
https://pubmed.ncbi.nlm.nih.gov/24824602
https://pubmed.ncbi.nlm.nih.gov/24824602
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30870 (2012)
PLoS ONE
PLoS ONE
Background An imprecise quantitative sense for the oscillating levels of proteins and their modifications, interactions, and translocations as a function of the cell cycle is fundamentally important for a cartoon/narrative understanding for how the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2efd01b2048cf671503b9eac6a83068
http://europepmc.org/articles/PMC3275612?pdf=render
http://europepmc.org/articles/PMC3275612?pdf=render
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 717
Computational models of biological processes are important building blocks in Systems Biology studies. Calibration and validation are two important steps for moving a mathematical model to a computational model. While calibration refers to finding nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::339ef42faac025d6ab02c4870417fba3
https://pubmed.ncbi.nlm.nih.gov/21370031
https://pubmed.ncbi.nlm.nih.gov/21370031