Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jayamani Anandhakumar"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 1, Pp 239-250 (2019)
The question of what determines whether cells are big or small has been the focus of many studies because it is thought that such determinants underpin the coupling of cell growth with cell division. In contrast, what determines the overall pattern o
Externí odkaz:
https://doaj.org/article/4449c04e655e4e3583b89913a9ed0c99
Hsf1 and Hsp70 constitute a two-component feedback loop that regulates the yeast heat shock response
Autor:
Joanna Krakowiak, Xu Zheng, Nikit Patel, Zoë A Feder, Jayamani Anandhakumar, Kendra Valerius, David S Gross, Ahmad S Khalil, David Pincus
Publikováno v:
eLife, Vol 7 (2018)
Models for regulation of the eukaryotic heat shock response typically invoke a negative feedback loop consisting of the transcriptional activator Hsf1 and a molecular chaperone. Previously we identified Hsp70 as the chaperone responsible for Hsf1 rep
Externí odkaz:
https://doaj.org/article/9744ad64198946c1bd0c7f5f1bb6fd82
Autor:
Philippe Materne, Enrique Vázquez, Mar Sánchez, Carlo Yague-Sanz, Jayamani Anandhakumar, Valerie Migeot, Francisco Antequera, Damien Hermand
Publikováno v:
eLife, Vol 5 (2016)
In fission yeast, the ste11 gene encodes the master regulator initiating the switch from vegetative growth to gametogenesis. In a previous paper, we showed that the methylation of H3K4 and consequent promoter nucleosome deacetylation repress ste11 in
Externí odkaz:
https://doaj.org/article/9ff5496c85fb4db0b921ddde5f33d784
Autor:
Philippe Materne, Jayamani Anandhakumar, Valerie Migeot, Ignacio Soriano, Carlo Yague-Sanz, Elena Hidalgo, Carole Mignion, Luis Quintales, Francisco Antequera, Damien Hermand
Publikováno v:
eLife, Vol 4 (2015)
The phosphorylation of the RNA polymerase II C-terminal domain (CTD) plays a key role in delineating transcribed regions within chromatin by recruiting histone methylases and deacetylases. Using genome-wide nucleosome mapping, we show that CTD S2 pho
Externí odkaz:
https://doaj.org/article/7766f9965c0843ab9fec4418e90c464f
Publikováno v:
PLoS Genetics, Vol 10, Iss 4, p e1004202 (2014)
It is widely accepted that transcriptional regulation of eukaryotic genes is intimately coupled to covalent modifications of the underlying chromatin template, and in certain cases the functional consequences of these modifications have been characte
Externí odkaz:
https://doaj.org/article/ed0be73318294e45a12ab179b5dc9c4b
Autor:
Ann De Vos, Jayamani Anandhakumar, Jeff Van den Brande, Mathias Verduyckt, Vanessa Franssens, Joris Winderickx, Erwin Swinnen
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2011 (2011)
Hyperphosphorylated and aggregated human protein tau constitutes a hallmark of a multitude of neurodegenerative diseases called tauopathies, exemplified by Alzheimer's disease. In spite of an enormous amount of research performed on tau biology, seve
Externí odkaz:
https://doaj.org/article/a74afcec3dfd438fb554d2f660cbcda4
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 1, Pp 239-250 (2019)
The question of what determines whether cells are big or small has been the focus of many studies because it is thought that such determinants underpin the coupling of cell growth with cell division. In contrast, what determines the overall pattern o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43778fe671567ae3d51da0a073e2ce8e
https://doi.org/10.1534/g3.118.200854
https://doi.org/10.1534/g3.118.200854
Autor:
Michael J. Guertin, Jayamani Anandhakumar, David S. Gross, David Pincus, Alexander M. Erkine, Prathapan Thiru
Publikováno v:
Molecular Biology of the Cell
Heat Shock Factor 1 (Hsf1) is the master transcriptional regulator of molecular chaperones and binds to the same cis-acting element - Heat Shock Element (HSE) - across the eukaryotic lineage. In budding yeast, Hsf1 drives transcription of ~20 genes e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7575bf00f1a81ee7d3629ca0b7b10c2c
http://europepmc.org/articles/PMC6340206
http://europepmc.org/articles/PMC6340206
Autor:
Amoldeep S. Kainth, Surabhi Chowdhary, Yara W. Moustafa, Jayamani Anandhakumar, David S. Gross
Publikováno v:
Molecular and Cellular Biology. 36:1943-1960
Mediator is an evolutionarily conserved coactivator complex essential for RNA polymerase II transcription. Although it has been generally assumed that in Saccharomyces cerevisiae, Mediator is a stable trimodular complex, its structural state in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5555d5bb11dd780ff0a2ff2f8a3098
https://doi.org/10.1128/mcb.00005-16
https://doi.org/10.1128/mcb.00005-16
Publikováno v:
G3: Genes|Genomes|Genetics
The question of what determines whether cells are big or small has been the focus of many studies because it is thought that such determinants underpin the coupling of cell growth with cell division. In contrast, what determines the overall pattern o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c08a5688e6622456318d625ee88ace5a
https://pubmed.ncbi.nlm.nih.gov/30463882
https://pubmed.ncbi.nlm.nih.gov/30463882