Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jayakumar S Poovassery"'
Autor:
John W Avery, Geoffrey M Smith, Simon O Owino, Demba Sarr, Tamas Nagy, Stephen Mwalimu, James Matthias, Lauren F Kelly, Jayakumar S Poovassery, Joab D Middii, Carlos Abramowsky, Julie M Moore
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31090 (2012)
Low birth weight and fetal loss are commonly attributed to malaria in endemic areas, but the cellular and molecular mechanisms that underlie these poor birth outcomes are incompletely understood. Increasing evidence suggests that dysregulated hemosta
Externí odkaz:
https://doaj.org/article/08cdd76a62a5408aa579a585d9fa66e9
Publikováno v:
International Journal of Cancer. 137:267-277
Dysregulated expression and/or mutations of the various components of the phosphoinositide 3-kinase (PI3K)/Akt pathway occur with high frequency in prostate cancer and are associated with the development and progression of castration resistant tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1ef5d6bbc249f6399b998248ffe0cb6
https://doi.org/10.1002/ijc.29378
https://doi.org/10.1002/ijc.29378
Engineering multivalent antibodies to target heregulin-induced HER3 signaling in breast cancer cells
Autor:
E. Sally Ward, Isabel M Manjarres, Raimund J. Ober, Pankaj Bansal, Sungyong You, Jeffrey C. Kang, Jayakumar S. Poovassery
Publikováno v:
mAbs
The use of antibodies in therapy and diagnosis has undergone an unprecedented expansion during the past two decades. This is due in part to innovations in antibody engineering that now offer opportunities for the production of “second generation”
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880d3397ad389a51caaec7ccdbe8c302
https://doi.org/10.4161/mabs.27658
https://doi.org/10.4161/mabs.27658
Publikováno v:
The Journal of Immunology. 189:1757-1764
Toll-like receptor 7 (TLR7) signals to B cells are critically involved in the innate immune response to microbes, as well as pathogenesis of autoimmune diseases, but the molecular mechanisms that normally regulate these responses are incompletely und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7989aa49edf2bdb302cbf08b59d5dd
https://doi.org/10.4049/jimmunol.1200624
https://doi.org/10.4049/jimmunol.1200624
Publikováno v:
Parasite Immunology. 34:224-235
The molecular mechanisms that underlie poor birth outcomes in malaria during pregnancy remain poorly defined. To assess the role of host immune responses, mice known to respond differentially to Plasmodium chabaudi AS infection were studied. Followin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::014ea475dccd9b95594ca3f2566718f1
https://doi.org/10.1111/j.1365-3024.2012.01355.x
https://doi.org/10.1111/j.1365-3024.2012.01355.x
Autor:
Claire M. Buchta, Jayakumar S. Poovassery, Gail A. Bishop, Joanne M Hildebrand, Zuoan Yi, Laura L. Stunz
Publikováno v:
Immunological Reviews. 244:55-74
A large and diverse group of receptors utilizes the family of cytoplasmic signaling proteins known as tumor necrosis factor receptor (TNFR)-associated factors (TRAFs). In recent years, there has been a resurgence of interest and exploration of the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10f2bed71cb9172ceed0386140a4faf1
https://doi.org/10.1111/j.1600-065x.2011.01055.x
https://doi.org/10.1111/j.1600-065x.2011.01055.x
Autor:
Mark L. Schultz, Laura L. Stunz, Jayakumar S. Poovassery, Sonja M. Smith, Gail A. Bishop, Ping Xie, Lindsey E. Carlin
Publikováno v:
Journal of Leukocyte Biology. 90:1149-1157
The key role of TRAF6 in TLR signaling pathways is well known. More recent evidence has implicated TRAF3 as another TRAF family member important to certain TLR responses of myeloid cells. Previous studies demonstrate that TRAF3 functions are highly c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7039e14f4ac813499be6b67ee79a2126
https://doi.org/10.1189/jlb.0111044
https://doi.org/10.1189/jlb.0111044
Publikováno v:
International journal of cancer. 137(2)
Dysregulated expression and/or mutations of the various components of the phosphoinositide 3-kinase (PI3K)/Akt pathway occur with high frequency in prostate cancer and are associated with the development and progression of castration resistant tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9d640180ed5190d52b3ad693f8f07f4
https://pubmed.ncbi.nlm.nih.gov/25471734
https://pubmed.ncbi.nlm.nih.gov/25471734
Autor:
Jayakumar S. Poovassery, Carlos Abramowsky, John Avery, Simon O. Owino, Joab D. Middii, Lauren F. Kelly, Julie M. Moore, Geoffrey M. Smith, Stephen M. Mwalimu, James Matthias, Demba Sarr, Tamas Nagy
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 2, p e31090 (2012)
PLoS ONE, Vol 7, Iss 2, p e31090 (2012)
Low birth weight and fetal loss are commonly attributed to malaria in endemic areas, but the cellular and molecular mechanisms that underlie these poor birth outcomes are incompletely understood. Increasing evidence suggests that dysregulated hemosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686ebc99538b3b39568b6f471f406129
http://europepmc.org/articles/PMC3274552
http://europepmc.org/articles/PMC3274552
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 183(8)
Although an important role for excessive proinflammatory cytokines in compromise of pregnancy has been established, an immunological basis for malaria-induced fetal loss remains to be demonstrated. In this study, the roles of IFN-γ and TNF in Plasmo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5dd53a23a8e31f3b38cf815a9b8d8e
https://pubmed.ncbi.nlm.nih.gov/19783682
https://pubmed.ncbi.nlm.nih.gov/19783682