Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jaya Sarin"'
Autor:
Balazs Acs, Fahad Shabbir Ahmed, Swati Gupta, Pok Fai Wong, Robyn D. Gartrell, Jaya Sarin Pradhan, Emanuelle M. Rizk, Bonnie Gould Rothberg, Yvonne M. Saenger, David L. Rimm
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Histology data exists for many cancer samples and the ability to automatically image this data may provide prognostic information. Here, the authors generated an algorithm to measure tumour infiltrating lymphocytes in melanoma histology specimens and
Externí odkaz:
https://doaj.org/article/aa7ab2f3684448649179b824d976a4d8
Autor:
Yvonne M. Saenger, Jing Wang, David L. Rimm, Tammie Ferringer, Zhe S. Chen, Basil A. Horst, Robert Phelps, Iman Osman, Michael R. Moore, Manas Mondal, Chen Yang, Emanuelle M. Rizk, Balazs Acs, Pok Fai Wong, Harriet M. Kluger, Larisa J. Geskin, Megan H. Trager, Bethany R. Rohr, Robyn D. Gartrell-Corrado, Jaya Sarin Pradhan, Eric J. Robinson, Prathamesh M. Kulkarni
Supplementary Data from Deep Learning Based on Standard H&E Images of Primary Melanoma Tumors Identifies Patients at Risk for Visceral Recurrence and Death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1119bebcd3df4ef630b4736ce23f3e49
https://doi.org/10.1158/1078-0432.22473240
https://doi.org/10.1158/1078-0432.22473240
Autor:
Yvonne M. Saenger, Jing Wang, David L. Rimm, Tammie Ferringer, Zhe S. Chen, Basil A. Horst, Robert Phelps, Iman Osman, Michael R. Moore, Manas Mondal, Chen Yang, Emanuelle M. Rizk, Balazs Acs, Pok Fai Wong, Harriet M. Kluger, Larisa J. Geskin, Megan H. Trager, Bethany R. Rohr, Robyn D. Gartrell-Corrado, Jaya Sarin Pradhan, Eric J. Robinson, Prathamesh M. Kulkarni
Purpose:Biomarkers for disease-specific survival (DSS) in early-stage melanoma are needed to select patients for adjuvant immunotherapy and accelerate clinical trial design. We present a pathology-based computational method using a deep neural networ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f12dd6e3ea5c13f1ea907c0b2e48c5f
https://doi.org/10.1158/1078-0432.c.6528453
https://doi.org/10.1158/1078-0432.c.6528453
Autor:
Brian A. Van Tine, Gulam Abbas Manji, Gary K. Schwartz, Angela C. Hirbe, Shing M. Lee, Andrew X. Chen, Jaya Sarin Pradhan, Raul Rabadan, Ilenia Pellicciotta, Alexander G. Raufi
Publikováno v:
Clinical Cancer Research. 27:5519-5527
Purpose: To evaluate the safety and tolerability in phase I first-in-human combination therapy with pexidartinib, an inhibitor of colony-stimulating factor-1 receptor, and sirolimus, an mTOR inhibitor, to target tumor-associated macrophage (TAM) pola
Autor:
Kuixi Zhu, Ayush C. Srivastava, Robyn D. Gartrell, Yvonne M. Saenger, Larisa J. Geskin, Branden Lau, Megan H. Trager, Michael Moore, Benjamin T. Fullerton, Sharon Rose, Rui Chang, Jaya Sarin Pradhan, Emanuelle M. Rizk, Gary Goldenberg, Giselle Singer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
The presence of actinic keratoses (AKs) increases a patient’s risk of developing squamous cell carcinoma by greater than six-fold. We evaluated the effect of topical treatment with imiquimod on the tumor microenvironment by measuring transcriptomic
Autor:
Eric Robinson, Jaya Sarin Pradhan, Bethany R. Rohr, Pok Fai Wong, Zhe Chen, Basil A. Horst, Tammie Ferringer, Yvonne M. Saenger, Robyn D. Gartrell-Corrado, Chen Yang, Prathamesh M. Kulkarni, Balazs Acs, Iman Osman, Manas Mondal, Michael Moore, Emanuelle M. Rizk, Harriet M. Kluger, Robert G. Phelps, Jing Wang, Larisa J. Geskin, Megan H. Trager, David L. Rimm
Publikováno v:
Clin Cancer Res
Purpose: Biomarkers for disease-specific survival (DSS) in early-stage melanoma are needed to select patients for adjuvant immunotherapy and accelerate clinical trial design. We present a pathology-based computational method using a deep neural netwo
Autor:
Adriana Lopez, Larisa J. Geskin, Claire Audrey-Bayan, Megan H. Trager, Yvonne M. Saenger, Douglas K. Marks, Andrew M. Silverman, Emanuelle M. Rizk, Jaya Sarin Pradhan, Robyn D. Gartrell-Corrado, George W. Niedt
Publikováno v:
Melanoma research. 30(4)
Response to talimogene laherparepvec (T-Vec) is difficult to assess as pigmented macrophages that have ingested melanoma cells ('melanophages') persist after injection, mimicking melanoma. We used quantitative immunofluorescence (qIF) to (1) distingu
Autor:
Yvonne M. Saenger, Emanuelle M. Rizk, Balazs Acs, Fahad Shabbir Ahmed, Swati Gupta, Bonnie E. Gould Rothberg, David L. Rimm, Pok Fai Wong, Robyn D. Gartrell, Jaya Sarin Pradhan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Nature Communications
Nature Communications
Assessment of tumor infiltrating lymphocytes (TILs) as a prognostic variable in melanoma has not seen broad adoption due to lack of standardization. Automation could represent a solution. Here, using open source software, we build an algorithm for im
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Akademický článek
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